| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fluvoxamine (maleate)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.125227 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0899623 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0838748 |
| ANGPTL4 | angiopoietin-like 4 | 0.076052 |
| SFTPA2 | surfactant protein A2 | 0.0698737 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0664982 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0603008 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.059357 |
| FMN1 | formin 1 | 0.0546043 |
| NRG3 | neuregulin 3 | 0.0527861 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.0482282 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0480614 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0428918 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0428353 |
| HDAC9 | histone deacetylase 9 | 0.0417936 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.038913 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0372578 |
| IFI44L | interferon-induced protein 44-like | 0.0364603 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0357369 |
| DST | dystonin | 0.0353378 |
| FLNA | filamin A, alpha | 0.0351783 |
| ASPH | aspartate beta-hydroxylase | 0.0350091 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0342693 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0336197 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0326343 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0323527 |
| RNF213 | ring finger protein 213 | 0.0317163 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0314502 |
| RRBP1 | ribosome binding protein 1 | 0.0298862 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0298117 |
| CTSB | cathepsin B | 0.0292122 |
| FHIT | fragile histidine triad | 0.029096 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0290809 |
| FMNL2 | formin-like 2 | 0.028511 |
| GOLGB1 | golgin B1 | 0.0284149 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0282774 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0281973 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0280788 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0278946 |
| B2M | beta-2-microglobulin | 0.0276421 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0271327 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0271157 |
| EHBP1 | EH domain binding protein 1 | 0.0269731 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0268385 |
| VEGFA | vascular endothelial growth factor A | 0.0266466 |
| RAD51B | RAD51 paralog B | 0.02633 |
| CFAP20DC | CFAP20 domain containing | 0.0258498 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0254961 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0254415 |
| PLSCR1 | phospholipid scramblase 1 | 0.0253257 |
| PLEC | plectin | 0.0250468 |
| HDAC4 | histone deacetylase 4 | 0.0249395 |
| RUNX1 | runt-related transcription factor 1 | 0.0247837 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0246435 |
| MELTF | melanotransferrin | 0.0245323 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0239999 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0238969 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0236276 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | 0.0233452 |
| NLGN1 | neuroligin 1 | 0.0233364 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0228937 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0227688 |
| SEPTIN9 | septin 9 | 0.0223695 |
| SON | SON DNA binding protein | 0.0221815 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0221003 |
| SVIL | supervillin | 0.0219485 |
| TPI1 | triosephosphate isomerase 1 | 0.0218041 |
| MSN | moesin | 0.0213185 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0210928 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0210571 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0209469 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0207301 |
| ADAR | adenosine deaminase, RNA-specific | 0.0205364 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0205255 |
| SUMF1 | sulfatase modifying factor 1 | 0.020356 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0202529 |
| OPHN1 | oligophrenin 1 | 0.0202282 |
| BRD2 | bromodomain containing 2 | 0.0201521 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0201094 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0200939 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0199283 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0195621 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0193286 |
| RPS3 | ribosomal protein S3 | 0.0192617 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0192403 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0192177 |
| CNKSR3 | CNKSR family member 3 | 0.0191823 |
| SKIL | SKI-like proto-oncogene | 0.0189831 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.018925 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0188205 |
| PRELID2 | PRELI domain containing 2 | 0.0188112 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0188087 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0186725 |
| FLNB | filamin B, beta | 0.0184898 |
| ATXN1 | ataxin 1 | 0.0184455 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0184176 |
| NRP2 | neuropilin 2 | 0.0184011 |
| SETBP1 | SET binding protein 1 | 0.018279 |
| CADM1 | cell adhesion molecule 1 | 0.0181775 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0181332 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.248738 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.174905 |
| VIM | vimentin | -0.162753 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.105268 |
| FN1 | fibronectin 1 | -0.0876928 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0714567 |
| UBC | ubiquitin C | -0.0704954 |
| ACTG1 | actin gamma 1 | -0.0603434 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0559693 |
| FTL | ferritin, light polypeptide | -0.04728 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0466167 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0463237 |
| TXNRD1 | thioredoxin reductase 1 | -0.0451064 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.045099 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0416652 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0403966 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0388072 |
| MT2A | metallothionein 2A | -0.0351899 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0348004 |
| RPLP1 | ribosomal protein, large, P1 | -0.0334614 |
| POTEF | POTE ankyrin domain family, member F | -0.0332847 |
| GOLGA4 | golgin A4 | -0.0331561 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0329391 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0316015 |
| LSAMP | limbic system-associated membrane protein | -0.0313742 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0300218 |
| USP3 | ubiquitin specific peptidase 3 | -0.0297987 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0288372 |
| ANLN | anillin, actin binding protein | -0.0283531 |
| RPL32 | ribosomal protein L32 | -0.0274681 |
| KPNB1 | karyopherin (importin) beta 1 | -0.027408 |
| RPL34 | ribosomal protein L34 | -0.0270454 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0268545 |
| TUBB | tubulin, beta class I | -0.0267914 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0267513 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0266223 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0261961 |
| RTN4 | reticulon 4 | -0.0257742 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0257244 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0256569 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0254865 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0254574 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.025441 |
| RPS6 | ribosomal protein S6 | -0.0253022 |
| RPS24 | ribosomal protein S24 | -0.0248534 |
| RPS23 | ribosomal protein S23 | -0.0247489 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0245768 |
| CLINT1 | clathrin interactor 1 | -0.0244313 |
| RPLP0 | ribosomal protein, large, P0 | -0.024121 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0238012 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0237675 |
| RHOA | ras homolog family member A | -0.0236096 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.023567 |
| SPAG9 | sperm associated antigen 9 | -0.0235533 |
| PTMA | prothymosin, alpha | -0.023403 |
| RPS5 | ribosomal protein S5 | -0.0232896 |
| EMP1 | epithelial membrane protein 1 | -0.023237 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0231652 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0230345 |
| TMEM263 | transmembrane protein 263 | -0.0227964 |
| OLA1 | Obg-like ATPase 1 | -0.0227467 |
| TMSB10 | thymosin beta 10 | -0.022662 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.022501 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0223164 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0219467 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0215638 |
| RHEB | Ras homolog enriched in brain | -0.0215626 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0215324 |
| WDR45B | WD repeat domain 45B | -0.0215194 |
| RLF | rearranged L-myc fusion | -0.0214369 |
| CALU | calumenin | -0.0212679 |
| RPL38 | ribosomal protein L38 | -0.0210279 |
| TFG | TRK-fused gene | -0.0209599 |
| CALR | calreticulin | -0.0209112 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0208618 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0208284 |
| RPS21 | ribosomal protein S21 | -0.020783 |
| RPL23 | ribosomal protein L23 | -0.0207446 |
| CCNI | cyclin I | -0.0203295 |
| S100A9 | S100 calcium binding protein A9 | -0.0203257 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0200739 |
| SETD5 | SET domain containing 5 | -0.0200359 |
| NF1 | neurofibromin 1 | -0.0200313 |
| RPS27A | ribosomal protein S27a | -0.019991 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0197288 |
| IER3 | immediate early response 3 | -0.0197229 |
| SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) | -0.0195064 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0193793 |
| VMP1 | vacuole membrane protein 1 | -0.0191386 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0191025 |
| RPL8 | ribosomal protein L8 | -0.0190939 |
| SRPK2 | SRSF protein kinase 2 | -0.0189892 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0189291 |
| RPL36A | ribosomal protein L36a | -0.0189246 |
| RBMX | RNA binding motif protein, X-linked | -0.0188687 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0188389 |
| PMEL | premelanosome protein | -0.0188334 |
| NKTR | natural killer cell triggering receptor | -0.0188129 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0187504 |
| SMYD3 | SET and MYND domain containing 3 | -0.0185725 |
