| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.144513 |
| BMP10 | bone morphogenetic protein 10 | 0.0471482 |
| HDAC9 | histone deacetylase 9 | 0.0459716 |
| PDGFC | platelet derived growth factor C | 0.0453267 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0443462 |
| VCL | vinculin | 0.0441074 |
| ANXA1 | annexin A1 | 0.0390108 |
| ZNF608 | zinc finger protein 608 | 0.0353424 |
| AHNAK | AHNAK nucleoprotein | 0.0348408 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0314119 |
| MYO5C | myosin VC | 0.0311698 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0305375 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0286732 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0282731 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0275759 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0273061 |
| FER1L6 | fer-1-like family member 6 | 0.025999 |
| MACROD2 | MACRO domain containing 2 | 0.0257198 |
| FOXP1 | forkhead box P1 | 0.0249248 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0245202 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0243257 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0240089 |
| RRM2 | ribonucleotide reductase M2 | 0.0221541 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0220207 |
| BCOR | BCL6 corepressor | 0.0218238 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0217047 |
| MKI67 | marker of proliferation Ki-67 | 0.0217019 |
| GLI3 | GLI family zinc finger 3 | 0.0211994 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0209806 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0207724 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0206619 |
| MYOF | myoferlin | 0.0202142 |
| TMSB4X | thymosin beta 4, X-linked | 0.020209 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0201751 |
| GSE1 | Gse1 coiled-coil protein | 0.019293 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0186923 |
| CORO1C | coronin, actin binding protein, 1C | 0.0186909 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0185912 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0183454 |
| RCOR1 | REST corepressor 1 | 0.0180915 |
| DIAPH3 | diaphanous-related formin 3 | 0.0177858 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0176719 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0169555 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0169111 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0169037 |
| CTBP2 | C-terminal binding protein 2 | 0.0165923 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0165136 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0163781 |
| AEBP2 | AE binding protein 2 | 0.0163573 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0162967 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0160641 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0154258 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0147155 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0145622 |
| H1-4 | H1.4 linker histone, cluster member | 0.0144708 |
| ANLN | anillin, actin binding protein | 0.0141069 |
| ITGA10 | integrin, alpha 10 | 0.0140969 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0140538 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0140291 |
| PDE7B | phosphodiesterase 7B | 0.014008 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0133697 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0132485 |
| CUL3 | cullin 3 | 0.0132047 |
| TXK | TXK tyrosine kinase | 0.0131488 |
| ECT2 | epithelial cell transforming 2 | 0.0129025 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | 0.0127808 |
| TMPO | thymopoietin | 0.0126489 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.0121918 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0119388 |
| BMP2K | BMP2 inducible kinase | 0.0118791 |
| SGMS2 | sphingomyelin synthase 2 | 0.0118593 |
| H4C15 | H4 clustered histone 15 | 0.0118064 |
| SUMF1 | sulfatase modifying factor 1 | 0.0117575 |
| IRX2 | iroquois homeobox 2 | 0.0115147 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0114519 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0114023 |
| RAB18 | RAB18, member RAS oncogene family | 0.0113804 |
| SSBP3 | single stranded DNA binding protein 3 | 0.011364 |
| FLNA | filamin A, alpha | 0.0113199 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0112962 |
| KIF11 | kinesin family member 11 | 0.0112068 |
| CRY1 | cryptochrome circadian clock 1 | 0.0111345 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | 0.0110891 |
| IGF2 | insulin-like growth factor 2 | 0.0110594 |
| TRIOBP | TRIO and F-actin binding protein | 0.0110077 |
| NCAPG | non-SMC condensin I complex, subunit G | 0.0109731 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.010896 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0108702 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0108693 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0108535 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0107045 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.010692 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0105379 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0104594 |
| IRS1 | insulin receptor substrate 1 | 0.0104383 |
| KNTC1 | kinetochore associated 1 | 0.0103943 |
| RPS2 | ribosomal protein S2 | 0.0103934 |
| AATF | apoptosis antagonizing transcription factor | 0.0103258 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0103199 |
| RRBP1 | ribosome binding protein 1 | 0.0102394 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.309145 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.090081 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0880844 |
| TXNRD1 | thioredoxin reductase 1 | -0.0880135 |
| S100A6 | S100 calcium binding protein A6 | -0.0797905 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0779318 |
| ACTG1 | actin gamma 1 | -0.0738104 |
| FLNB | filamin B, beta | -0.070596 |
| GOLGA4 | golgin A4 | -0.0648435 |
| RTN4 | reticulon 4 | -0.0598466 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0579784 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0550895 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0540654 |
| PTMA | prothymosin, alpha | -0.0513428 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0505808 |
| RPS23 | ribosomal protein S23 | -0.0501092 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0501078 |
| RPS19 | ribosomal protein S19 | -0.0498093 |
| SMYD3 | SET and MYND domain containing 3 | -0.0497421 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0484956 |
| RPS13 | ribosomal protein S13 | -0.0483085 |
| RPL11 | ribosomal protein L11 | -0.0481533 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.048048 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0479979 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0478265 |
| RPS6 | ribosomal protein S6 | -0.0476805 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0464115 |
| SBF2 | SET binding factor 2 | -0.0455438 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0435487 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0431955 |
| GPHN | gephyrin | -0.041662 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0415318 |
| RPL13A | ribosomal protein L13a | -0.0414792 |
| TMSB10 | thymosin beta 10 | -0.0402436 |
| NBEA | neurobeachin | -0.0399283 |
| RPS29 | ribosomal protein S29 | -0.0398373 |
| ANK2 | ankyrin 2, neuronal | -0.039604 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0391135 |
| RPLP0 | ribosomal protein, large, P0 | -0.0383884 |
| PKM | pyruvate kinase, muscle | -0.0382873 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.037921 |
| PFN1 | profilin 1 | -0.0377508 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0369685 |
| RPL19 | ribosomal protein L19 | -0.0368524 |
| JMJD1C | jumonji domain containing 1C | -0.0365008 |
| RPS8 | ribosomal protein S8 | -0.0358164 |
| LDHA | lactate dehydrogenase A | -0.0347045 |
| TMEM41B | transmembrane protein 41B | -0.0345974 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0345312 |
| COG5 | component of oligomeric golgi complex 5 | -0.0341783 |
| RPLP2 | ribosomal protein, large, P2 | -0.0340535 |
| USP34 | ubiquitin specific peptidase 34 | -0.0338777 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0337539 |
| NFIA | nuclear factor I/A | -0.0337124 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0335755 |
| METTL15 | methyltransferase like 15 | -0.0334185 |
| RBM25 | RNA binding motif protein 25 | -0.0333583 |
| B2M | beta-2-microglobulin | -0.0331078 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0329573 |
| NF1 | neurofibromin 1 | -0.0325976 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0324806 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0324583 |
| SQSTM1 | sequestosome 1 | -0.0323969 |
| RPL32 | ribosomal protein L32 | -0.0323451 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0321546 |
| RPL27A | ribosomal protein L27a | -0.0319299 |
| AHI1 | Abelson helper integration site 1 | -0.0316709 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0315384 |
| RPL5 | ribosomal protein L5 | -0.031525 |
| RHBDD1 | rhomboid domain containing 1 | -0.0311141 |
| SRPK2 | SRSF protein kinase 2 | -0.0310901 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0307554 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0300741 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0297458 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0296259 |
| DIAPH2 | diaphanous-related formin 2 | -0.0295425 |
| PARD3 | par-3 family cell polarity regulator | -0.0295085 |
| NBAS | neuroblastoma amplified sequence | -0.0291551 |
| CCNI | cyclin I | -0.0290526 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0288926 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0288599 |
| RPS25 | ribosomal protein S25 | -0.028729 |
| PTEN | phosphatase and tensin homolog | -0.0285436 |
| RPL37A | ribosomal protein L37a | -0.0284815 |
| RPLP1 | ribosomal protein, large, P1 | -0.0284161 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0282013 |
| S100A9 | S100 calcium binding protein A9 | -0.0281835 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0280485 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0277651 |
| RPL28 | ribosomal protein L28 | -0.0276801 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0274895 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0271204 |
| PHIP | pleckstrin homology domain interacting protein | -0.0270362 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0269083 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0268358 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0268259 |
| POTEF | POTE ankyrin domain family, member F | -0.026497 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0263664 |
| RPL12 | ribosomal protein L12 | -0.0261947 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0261325 |
