| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fluvoxamine (maleate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.146618 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.13344 |
| VEGFA | vascular endothelial growth factor A | 0.106513 |
| ADM | adrenomedullin | 0.104097 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.103558 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0735897 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0721251 |
| MSN | moesin | 0.0610078 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0575787 |
| SFTPA2 | surfactant protein A2 | 0.0549554 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0530077 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0507835 |
| NAV2 | neuron navigator 2 | 0.0495261 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0468416 |
| NDRG1 | N-myc downstream regulated 1 | 0.046614 |
| B2M | beta-2-microglobulin | 0.0465027 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0457007 |
| MYOF | myoferlin | 0.0455678 |
| FMNL2 | formin-like 2 | 0.044289 |
| PCBP2 | poly(rC) binding protein 2 | 0.0421123 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0405023 |
| PLIN2 | perilipin 2 | 0.039109 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0390968 |
| PDE10A | phosphodiesterase 10A | 0.0383206 |
| MT2A | metallothionein 2A | 0.0381524 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0375757 |
| STC1 | stanniocalcin 1 | 0.0372302 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0348465 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0343591 |
| RPS12 | ribosomal protein S12 | 0.0342669 |
| SYNJ2 | synaptojanin 2 | 0.0335969 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0332857 |
| BRD2 | bromodomain containing 2 | 0.0328679 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0323161 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.031552 |
| DUSP10 | dual specificity phosphatase 10 | 0.0311973 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0311059 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.030829 |
| CD44 | CD44 molecule (Indian blood group) | 0.0305811 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0305317 |
| CCNL1 | cyclin L1 | 0.0289684 |
| RPL37A | ribosomal protein L37a | 0.0288116 |
| CADM1 | cell adhesion molecule 1 | 0.0285133 |
| GOLGA4 | golgin A4 | 0.0282772 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0276864 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0276131 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0276087 |
| C3 | complement component 3 | 0.0265924 |
| VIM | vimentin | 0.0264624 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0261662 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0261043 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0260501 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.025511 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0249981 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0248595 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0248416 |
| IRS2 | insulin receptor substrate 2 | 0.024525 |
| STC2 | stanniocalcin 2 | 0.0243415 |
| DUSP5 | dual specificity phosphatase 5 | 0.023903 |
| VCAN | versican | 0.0238561 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0234986 |
| RPS3 | ribosomal protein S3 | 0.0229003 |
| FTL | ferritin, light polypeptide | 0.0227278 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0225271 |
| PRRC2C | proline-rich coiled-coil 2C | 0.022523 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0221521 |
| RPL9 | ribosomal protein L9 | 0.0218337 |
| RPS14 | ribosomal protein S14 | 0.0210873 |
| RPLP2 | ribosomal protein, large, P2 | 0.0210008 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0208587 |
| RPS17 | ribosomal protein S17 | 0.020478 |
| MLPH | melanophilin | 0.0203962 |
| ATF4 | activating transcription factor 4 | 0.0201885 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0201722 |
| ARRDC3 | arrestin domain containing 3 | 0.0200702 |
| RPL27 | ribosomal protein L27 | 0.0195577 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0194015 |
| FAM13A | family with sequence similarity 13, member A | 0.0193958 |
| FLNB | filamin B, beta | 0.0193688 |
| CTSB | cathepsin B | 0.0193314 |
| WWOX | WW domain containing oxidoreductase | 0.0191274 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0187869 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0187574 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0186818 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0186809 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0184199 |
| ZFP36 | ZFP36 ring finger protein | 0.018369 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0181754 |
| ENO1 | enolase 1, (alpha) | 0.018034 |
| DEPP1 | DEPP autophagy regulator 1 | 0.0180207 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0178273 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0175624 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0174823 |
| CD109 | CD109 molecule | 0.0173154 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0173138 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0170657 |
| MYO10 | myosin X | 0.0169562 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0169527 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0168997 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0167123 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | -0.273159 |
| FN1 | fibronectin 1 | -0.182479 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.14497 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.128429 |
| GLIS3 | GLIS family zinc finger 3 | -0.114826 |
| VCL | vinculin | -0.109572 |
| BICC1 | BicC family RNA binding protein 1 | -0.0994356 |
| DST | dystonin | -0.0920577 |
| FRMD4A | FERM domain containing 4A | -0.0782718 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0712259 |
| AHNAK | AHNAK nucleoprotein | -0.0686789 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0638633 |
| NABP1 | nucleic acid binding protein 1 | -0.060349 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0586545 |
| HMGA2 | high mobility group AT-hook 2 | -0.0584677 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0544819 |
| THBS1 | thrombospondin 1 | -0.0540546 |
| CANX | calnexin | -0.0527889 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0518746 |
| DIAPH2 | diaphanous-related formin 2 | -0.0517039 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0517028 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0513082 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0485168 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0483138 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0477688 |
| TUBB | tubulin, beta class I | -0.0476618 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0472454 |
| GNAS | GNAS complex locus | -0.0465808 |
| RIGI | RNA sensor RIG-I | -0.045957 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0457626 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0456618 |
| FAM20C | family with sequence similarity 20, member C | -0.0449149 |
| IER3 | immediate early response 3 | -0.0440927 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0432793 |
| KYNU | kynureninase | -0.0429804 |
| HLA-B | major histocompatibility complex, class I, B | -0.0421438 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0419581 |
| EHBP1 | EH domain binding protein 1 | -0.0415886 |
| HLA-E | major histocompatibility complex, class I, E | -0.0415471 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0414548 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0414136 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.040882 |
| PHF3 | PHD finger protein 3 | -0.0407299 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0405727 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.040492 |
| PALLD | palladin, cytoskeletal associated protein | -0.0400878 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0393554 |
| RAI14 | retinoic acid induced 14 | -0.0391464 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.039075 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0388555 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0385859 |
| ACTG1 | actin gamma 1 | -0.0383616 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0380543 |
| SMAD3 | SMAD family member 3 | -0.0378551 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0369655 |
| AFF4 | AF4/FMR2 family, member 4 | -0.036552 |
| SMYD3 | SET and MYND domain containing 3 | -0.0364412 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0355809 |
| TMEM263 | transmembrane protein 263 | -0.0341499 |
| OSMR | oncostatin M receptor | -0.0339478 |
| SBF2 | SET binding factor 2 | -0.0338859 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0331953 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0323308 |
| HDAC8 | histone deacetylase 8 | -0.0321469 |
| NF1 | neurofibromin 1 | -0.031726 |
| UBC | ubiquitin C | -0.0316626 |
| SP100 | SP100 nuclear antigen | -0.031609 |
| CLIC4 | chloride intracellular channel 4 | -0.0312003 |
| PGK1 | phosphoglycerate kinase 1 | -0.0309628 |
| RPS24 | ribosomal protein S24 | -0.0309527 |
| XAF1 | XIAP associated factor 1 | -0.030686 |
| KPNB1 | karyopherin (importin) beta 1 | -0.030659 |
| THBS2 | thrombospondin 2 | -0.0306574 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0302701 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0299939 |
| TMEM123 | transmembrane protein 123 | -0.0298039 |
| ANXA2 | annexin A2 | -0.0295588 |
| RNF213 | ring finger protein 213 | -0.0287607 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0285121 |
| HDLBP | high density lipoprotein binding protein | -0.0283894 |
| STK17A | serine/threonine kinase 17a | -0.0283007 |
| ANLN | anillin, actin binding protein | -0.0282066 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0281775 |
| TAOK1 | TAO kinase 1 | -0.0279705 |
| SDCBP | syndecan binding protein (syntenin) | -0.0278251 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0275646 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0270384 |
| VMP1 | vacuole membrane protein 1 | -0.0270299 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.026897 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0267669 |
| CAVIN1 | caveolae associated protein 1 | -0.0266286 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0263435 |
| MORF4L2 | mortality factor 4 like 2 | -0.0263073 |
| GOLGB1 | golgin B1 | -0.026259 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.026209 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0261636 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.025943 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0258855 |
| RPL4 | ribosomal protein L4 | -0.0255847 |
| CNTN6 | contactin 6 | -0.0254543 |
