| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.171862 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.13938 |
| MT2A | metallothionein 2A | 0.0877192 |
| B2M | beta-2-microglobulin | 0.0857649 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0819581 |
| FAM13A | family with sequence similarity 13, member A | 0.0808521 |
| KYNU | kynureninase | 0.0806579 |
| ENO1 | enolase 1, (alpha) | 0.0778351 |
| VEGFA | vascular endothelial growth factor A | 0.0747989 |
| STC1 | stanniocalcin 1 | 0.0660314 |
| CANX | calnexin | 0.064627 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0589919 |
| SPAG9 | sperm associated antigen 9 | 0.0565793 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0536426 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0510413 |
| ARRDC3 | arrestin domain containing 3 | 0.050312 |
| HLA-A | major histocompatibility complex, class I, A | 0.0481717 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0467733 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0448344 |
| BRD2 | bromodomain containing 2 | 0.0441261 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0428787 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.042578 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0423203 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0411397 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0397485 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0396447 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0396114 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0389975 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0387041 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0384697 |
| SON | SON DNA binding protein | 0.0384529 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0379495 |
| RNF145 | ring finger protein 145 | 0.0376968 |
| ADM | adrenomedullin | 0.0374343 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0372388 |
| ATP13A3 | ATPase type 13A3 | 0.0355418 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0354041 |
| MSN | moesin | 0.0345501 |
| RPS8 | ribosomal protein S8 | 0.034372 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0337229 |
| FLNA | filamin A, alpha | 0.0332355 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0331592 |
| HIP1 | huntingtin interacting protein 1 | 0.0331351 |
| RNF216 | ring finger protein 216 | 0.032766 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0324675 |
| SEC61G | Sec61 gamma subunit | 0.0321127 |
| IL6 | interleukin 6 | 0.0320678 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0320423 |
| RPL37A | ribosomal protein L37a | 0.031451 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0313426 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0311748 |
| SLC39A9 | solute carrier family 39, member 9 | 0.0311514 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0306441 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0306097 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0302555 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0299842 |
| INSIG2 | insulin induced gene 2 | 0.0298959 |
| GOLGA4 | golgin A4 | 0.0291692 |
| YAP1 | Yes-associated protein 1 | 0.0286161 |
| YEATS2 | YEATS domain containing 2 | 0.0284181 |
| OXSR1 | oxidative stress responsive 1 | 0.0284045 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0282101 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0281812 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0280676 |
| RYBP | RING1 and YY1 binding protein | 0.0279085 |
| RPL11 | ribosomal protein L11 | 0.0278429 |
| CD44 | CD44 molecule (Indian blood group) | 0.0276491 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0276417 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0276228 |
| FOXO3 | forkhead box O3 | 0.0274256 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0274034 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0273887 |
| SEM1 | SEM1 26S proteasome subunit | 0.0273062 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0272965 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0272 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0270025 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.026956 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0269507 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.026772 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0262826 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0261913 |
| ZNF638 | zinc finger protein 638 | 0.0259028 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0258321 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0257288 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0256263 |
| EPAS1 | endothelial PAS domain protein 1 | 0.025335 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0253296 |
| SNX9 | sorting nexin 9 | 0.0251948 |
| PRELID2 | PRELI domain containing 2 | 0.0250786 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0250347 |
| TMEM165 | transmembrane protein 165 | 0.0249024 |
| SOCS5 | suppressor of cytokine signaling 5 | 0.0248314 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0247655 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0247624 |
| XPO1 | exportin 1 | 0.0247496 |
| CALU | calumenin | 0.0246776 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0245987 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0245142 |
| SEC24A | SEC24 family member A | 0.024459 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0242017 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.297434 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.144756 |
| LOX | lysyl oxidase | -0.117675 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0960307 |
| HMGA2 | high mobility group AT-hook 2 | -0.0938608 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0927899 |
| COL1A1 | collagen, type I, alpha 1 | -0.0825222 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0792123 |
| LOXL2 | lysyl oxidase-like 2 | -0.0685531 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0636455 |
| PKM | pyruvate kinase, muscle | -0.0635905 |
| CALD1 | caldesmon 1 | -0.0625933 |
| CDH13 | cadherin 13 | -0.0602032 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0600972 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0587416 |
| COL1A2 | collagen, type I, alpha 2 | -0.0557582 |
| NDRG1 | N-myc downstream regulated 1 | -0.0515438 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0508463 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0490988 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0482107 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.048166 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0430437 |
| PRSS23 | protease, serine, 23 | -0.0420788 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0416654 |
| TUBB | tubulin, beta class I | -0.0408972 |
| LDHA | lactate dehydrogenase A | -0.0393926 |
| ACTG1 | actin gamma 1 | -0.0387591 |
| TAGLN2 | transgelin 2 | -0.0387181 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0385567 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.03695 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0363282 |
| TNNC1 | troponin C type 1 (slow) | -0.0362935 |
| RASAL2 | RAS protein activator like 2 | -0.0359147 |
| VCL | vinculin | -0.0346619 |
| SRPK2 | SRSF protein kinase 2 | -0.0345513 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0335268 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0329584 |
| TMEM123 | transmembrane protein 123 | -0.0327575 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0327181 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0325545 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0321125 |
| RRBP1 | ribosome binding protein 1 | -0.0318852 |
| NKTR | natural killer cell triggering receptor | -0.0305614 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0305116 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.030371 |
| TMSB10 | thymosin beta 10 | -0.0302348 |
| TNS3 | tensin 3 | -0.0301885 |
| FUS | FUS RNA binding protein | -0.029558 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0294007 |
| HM13 | histocompatibility (minor) 13 | -0.02891 |
| NRP1 | neuropilin 1 | -0.0287322 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0286193 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0284625 |
| JAZF1 | JAZF zinc finger 1 | -0.0283144 |
| PLCB4 | phospholipase C, beta 4 | -0.0282719 |
| COL5A1 | collagen, type V, alpha 1 | -0.027487 |
| GLIS3 | GLIS family zinc finger 3 | -0.0273695 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0273617 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0268131 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0267104 |
| SYNPO | synaptopodin | -0.0265692 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0264052 |
| MAP4 | microtubule-associated protein 4 | -0.0261085 |
| SDC4 | syndecan 4 | -0.0258801 |
| CADM1 | cell adhesion molecule 1 | -0.0257879 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0255879 |
| CDK6 | cyclin-dependent kinase 6 | -0.02534 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.025252 |
| DIAPH3 | diaphanous-related formin 3 | -0.025121 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0250775 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0250572 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0248474 |
| PALLD | palladin, cytoskeletal associated protein | -0.0247249 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0247034 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0246935 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0245985 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0244185 |
| COL5A2 | collagen, type V, alpha 2 | -0.0243545 |
| TENM3 | teneurin transmembrane protein 3 | -0.0231481 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0228142 |
| FTO | fat mass and obesity associated | -0.0227951 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0226301 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0226182 |
| FBN1 | fibrillin 1 | -0.022561 |
| SERF2 | small EDRK-rich factor 2 | -0.0225501 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0222404 |
| AK1 | adenylate kinase 1 | -0.0222012 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.022171 |
| GNAS | GNAS complex locus | -0.0221272 |
| FN1 | fibronectin 1 | -0.0221215 |
| MAP1B | microtubule-associated protein 1B | -0.0220643 |
| WNT5B | wingless-type MMTV integration site family, member 5B | -0.0219193 |
| ETV6 | ets variant 6 | -0.0218296 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.021807 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0217538 |
| TPM4 | tropomyosin 4 | -0.021712 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0216863 |
| HDLBP | high density lipoprotein binding protein | -0.0216505 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.021457 |
| GANAB | glucosidase, alpha; neutral AB | -0.021261 |
