| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.141911 |
| CD44 | CD44 molecule (Indian blood group) | 0.112915 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0858904 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0847889 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0775286 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0659095 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.061752 |
| FMNL2 | formin-like 2 | 0.0604194 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0581886 |
| PKM | pyruvate kinase, muscle | 0.0558707 |
| RPS12 | ribosomal protein S12 | 0.051428 |
| B2M | beta-2-microglobulin | 0.0503574 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0471559 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0466537 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0462288 |
| SMAD3 | SMAD family member 3 | 0.0448879 |
| RPS3 | ribosomal protein S3 | 0.043977 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0436939 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0436513 |
| ARRDC3 | arrestin domain containing 3 | 0.0411532 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0405069 |
| PCBP2 | poly(rC) binding protein 2 | 0.0399971 |
| TXNIP | thioredoxin interacting protein | 0.0398712 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0394621 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0394579 |
| SFTPA2 | surfactant protein A2 | 0.0389402 |
| MATR3 | matrin 3 | 0.0383455 |
| RACK1 | receptor for activated C kinase 1 | 0.0383019 |
| TPI1 | triosephosphate isomerase 1 | 0.0381967 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0380074 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0374049 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0357232 |
| BRD2 | bromodomain containing 2 | 0.0356735 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.03562 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0354124 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0351806 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0350074 |
| RPL15 | ribosomal protein L15 | 0.03466 |
| SET | SET nuclear proto-oncogene | 0.0338519 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.033707 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0335113 |
| FLNA | filamin A, alpha | 0.0332969 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.033213 |
| ENO1 | enolase 1, (alpha) | 0.0327554 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0327256 |
| CCNL1 | cyclin L1 | 0.0326495 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0319435 |
| GOLGA4 | golgin A4 | 0.0307716 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 0.0298553 |
| TJP1 | tight junction protein 1 | 0.029855 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0298305 |
| RPS27A | ribosomal protein S27a | 0.0296459 |
| RPL36 | ribosomal protein L36 | 0.029618 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0292931 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0292106 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0287353 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.028721 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0285778 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0284563 |
| ZNF638 | zinc finger protein 638 | 0.0284224 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0282909 |
| RPL11 | ribosomal protein L11 | 0.0278767 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.027629 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0275915 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0274127 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0272834 |
| SLMAP | sarcolemma associated protein | 0.0268026 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0267342 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0261446 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0257702 |
| MSN | moesin | 0.0253583 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0253032 |
| MAP1B | microtubule-associated protein 1B | 0.0252542 |
| RPL12 | ribosomal protein L12 | 0.0251573 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0249301 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0249122 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0249078 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0244526 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0243198 |
| HPCAL1 | hippocalcin-like 1 | 0.0242015 |
| ATRN | attractin | 0.0241757 |
| SVIL | supervillin | 0.0240925 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0240026 |
| PNN | pinin, desmosome associated protein | 0.0238005 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.023725 |
| RPL37A | ribosomal protein L37a | 0.0235167 |
| PTMA | prothymosin, alpha | 0.0233869 |
| CUL3 | cullin 3 | 0.0231852 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0230781 |
| DENND4A | DENN/MADD domain containing 4A | 0.0229625 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.022818 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0227896 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0225202 |
| TMF1 | TATA element modulatory factor 1 | 0.0224397 |
| USP8 | ubiquitin specific peptidase 8 | 0.022338 |
| VIM | vimentin | 0.0221029 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0220433 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0217936 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0217846 |
| RUNX1 | runt-related transcription factor 1 | 0.021742 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.389475 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0661855 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0651521 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0547159 |
| ATG7 | autophagy related 7 | -0.0527958 |
| IGF2 | insulin-like growth factor 2 | -0.0503192 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0502154 |
| HMGA2 | high mobility group AT-hook 2 | -0.0478235 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.046473 |
| AHNAK | AHNAK nucleoprotein | -0.0452629 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0452298 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0450419 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0440205 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0439155 |
| GNAS | GNAS complex locus | -0.0428318 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0418489 |
| GPC6 | glypican 6 | -0.0415796 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0398807 |
| NF1 | neurofibromin 1 | -0.0398489 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0392534 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0392273 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0387698 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0380865 |
| TMEM123 | transmembrane protein 123 | -0.0379281 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0368213 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0364392 |
| DNER | delta/notch-like EGF repeat containing | -0.0354988 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0353269 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0342892 |
| RIN2 | Ras and Rab interactor 2 | -0.0342647 |
| PRR16 | proline rich 16 | -0.0335562 |
| CAVIN1 | caveolae associated protein 1 | -0.0332495 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0331196 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0329384 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0320187 |
| TMEM263 | transmembrane protein 263 | -0.0317342 |
| RIGI | RNA sensor RIG-I | -0.0314015 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0313528 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0310902 |
| TPM4 | tropomyosin 4 | -0.0306703 |
| FMN1 | formin 1 | -0.0305555 |
| TAOK1 | TAO kinase 1 | -0.0304938 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0304347 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0299472 |
| SNX14 | sorting nexin 14 | -0.029699 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0292438 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0292122 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0289818 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0287641 |
| ACER3 | alkaline ceramidase 3 | -0.0286445 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0279791 |
| FUS | FUS RNA binding protein | -0.027684 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0276484 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0276448 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0276175 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0274526 |
| DEK | DEK proto-oncogene | -0.0273173 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0272098 |
| CCNI | cyclin I | -0.0271496 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0266286 |
| ATM | ATM serine/threonine kinase | -0.0265087 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0263537 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0263333 |
| FBXO11 | F-box protein 11 | -0.0261388 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0259315 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0259128 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0257798 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0257494 |
| BSG | basigin (Ok blood group) | -0.0254909 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0254233 |
| THBS1 | thrombospondin 1 | -0.0253866 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0253375 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0251976 |
| RAI14 | retinoic acid induced 14 | -0.025183 |
| NALCN | sodium leak channel, non selective | -0.0251404 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0249716 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0248315 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0248281 |
| PODXL | podocalyxin-like | -0.0246934 |
| ZNF609 | zinc finger protein 609 | -0.0244704 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0243944 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0240483 |
| RPL34 | ribosomal protein L34 | -0.0240264 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0239346 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0238808 |
| VCL | vinculin | -0.0238516 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0238406 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0238064 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0237938 |
| SDC4 | syndecan 4 | -0.0237935 |
| TVP23C-CDRT4 | TVP23C-CDRT4 readthrough | -0.0237694 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0234736 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0233751 |
| PHF21A | PHD finger protein 21A | -0.0233394 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0233284 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0231819 |
| RAD51B | RAD51 paralog B | -0.0231329 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.023097 |
| ZNF33A | zinc finger protein 33A | -0.0229489 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.022857 |
