| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.230047 |
| SFTPA2 | surfactant protein A2 | 0.0759131 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.073984 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0655472 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.064011 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0639797 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0608604 |
| VEGFA | vascular endothelial growth factor A | 0.0598033 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.057712 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0556725 |
| B2M | beta-2-microglobulin | 0.0535247 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0510559 |
| STC2 | stanniocalcin 2 | 0.0504582 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.048915 |
| PLIN2 | perilipin 2 | 0.0484631 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0473707 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0458155 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0415751 |
| TPM3 | tropomyosin 3 | 0.039371 |
| RNF145 | ring finger protein 145 | 0.0390852 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0354425 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0352597 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0347083 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0345044 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0343728 |
| PCBP2 | poly(rC) binding protein 2 | 0.0342107 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0340099 |
| RACK1 | receptor for activated C kinase 1 | 0.0329554 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0323189 |
| TXNIP | thioredoxin interacting protein | 0.0315998 |
| FAM13A | family with sequence similarity 13, member A | 0.0306456 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0306222 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0304417 |
| NTN4 | netrin 4 | 0.0301606 |
| FAT1 | FAT atypical cadherin 1 | 0.0294358 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0284367 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.028006 |
| TXNRD1 | thioredoxin reductase 1 | 0.027397 |
| SVIL | supervillin | 0.0271208 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0270166 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0266486 |
| IRS2 | insulin receptor substrate 2 | 0.0265047 |
| DOCK5 | dedicator of cytokinesis 5 | 0.026405 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0261566 |
| TOP1 | topoisomerase (DNA) I | 0.0255411 |
| FTL | ferritin, light polypeptide | 0.0254514 |
| TCIM | transcriptional and immune response regulator | 0.025324 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0251008 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0246536 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0245712 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0241859 |
| ERBIN | erbb2 interacting protein | 0.0241698 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0238994 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.023511 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0234833 |
| FLNA | filamin A, alpha | 0.0233809 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0231688 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0230982 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0227685 |
| RPS12 | ribosomal protein S12 | 0.0226266 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0225654 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0222068 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0219276 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0218026 |
| YBX3 | Y box binding protein 3 | 0.0216712 |
| AREG | amphiregulin | 0.0213865 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.0212637 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.021161 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0210284 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0210133 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0209131 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.020714 |
| GOLGA4 | golgin A4 | 0.0207114 |
| FOSL1 | FOS-like antigen 1 | 0.0207039 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0206277 |
| COPA | coatomer protein complex, subunit alpha | 0.0206228 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0204685 |
| TMEM156 | transmembrane protein 156 | 0.0203269 |
| MYO1B | myosin IB | 0.0201846 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0201367 |
| DUSP5 | dual specificity phosphatase 5 | 0.0201036 |
| CCNL1 | cyclin L1 | 0.019958 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0198474 |
| ZRANB1 | zinc finger, RAN-binding domain containing 1 | 0.0197747 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.019373 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0193519 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0193402 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0191494 |
| FMNL2 | formin-like 2 | 0.0190762 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0189469 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0187931 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0187659 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0186313 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0185344 |
| CTBP2 | C-terminal binding protein 2 | 0.0184827 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0184423 |
| CD109 | CD109 molecule | 0.0184358 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.018423 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0184044 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0182977 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.403099 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.252587 |
| NRG1 | neuregulin 1 | -0.207134 |
| FN1 | fibronectin 1 | -0.194736 |
| HMGA2 | high mobility group AT-hook 2 | -0.121858 |
| SQSTM1 | sequestosome 1 | -0.101785 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0911378 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.07773 |
| HLA-B | major histocompatibility complex, class I, B | -0.0723201 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0673532 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0650543 |
| ITGA1 | integrin, alpha 1 | -0.062786 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0590624 |
| AEBP2 | AE binding protein 2 | -0.0576471 |
| VCL | vinculin | -0.056803 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0527463 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0523815 |
| GLIS3 | GLIS family zinc finger 3 | -0.0507329 |
| ACTG1 | actin gamma 1 | -0.0506107 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0495069 |
| IER3 | immediate early response 3 | -0.046887 |
| GNAS | GNAS complex locus | -0.0447714 |
| S100A6 | S100 calcium binding protein A6 | -0.0434799 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0434 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0415546 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0413542 |
| SYT1 | synaptotagmin I | -0.0409401 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0389005 |
| EFNA5 | ephrin-A5 | -0.038222 |
| FAM20C | family with sequence similarity 20, member C | -0.0380831 |
| LRRC23 | leucine rich repeat containing 23 | -0.0365552 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0358115 |
| TMEM263 | transmembrane protein 263 | -0.0355561 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0353356 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0352641 |
| RPL38 | ribosomal protein L38 | -0.0352633 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0342607 |
| RAI14 | retinoic acid induced 14 | -0.0339952 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0337751 |
| RPS24 | ribosomal protein S24 | -0.0337422 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0337397 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.032986 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.031617 |
| ETV6 | ets variant 6 | -0.0304569 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0287369 |
| TNS3 | tensin 3 | -0.0287042 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0284796 |
| S100A10 | S100 calcium binding protein A10 | -0.0284682 |
| HDLBP | high density lipoprotein binding protein | -0.0277445 |
| TENM4 | teneurin transmembrane protein 4 | -0.0274807 |
| TGFA | transforming growth factor, alpha | -0.0274198 |
| ARF1 | ADP-ribosylation factor 1 | -0.0273247 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0272407 |
| CANX | calnexin | -0.0271223 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0271092 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0270115 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0267966 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0267075 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0266512 |
| TMEM165 | transmembrane protein 165 | -0.0262723 |
| TMSB10 | thymosin beta 10 | -0.0262695 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0262533 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0261672 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0256374 |
| RPS29 | ribosomal protein S29 | -0.0244974 |
| BPTF | bromodomain PHD finger transcription factor | -0.0244294 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0242157 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0239237 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0237938 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0236404 |
| CTSD | cathepsin D | -0.0232451 |
| PRELID2 | PRELI domain containing 2 | -0.0231065 |
| RPS11 | ribosomal protein S11 | -0.0228732 |
| HPCAL1 | hippocalcin-like 1 | -0.0228649 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0225843 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0224831 |
| PKM | pyruvate kinase, muscle | -0.0224335 |
| CALU | calumenin | -0.0222751 |
| RPS20 | ribosomal protein S20 | -0.0221444 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0218799 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0217566 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0215483 |
| SMIM14 | small integral membrane protein 14 | -0.0214794 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0210552 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0203175 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0201755 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0201011 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0199588 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0199073 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0198792 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0197902 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0196059 |
| XAF1 | XIAP associated factor 1 | -0.0195786 |
| SMYD3 | SET and MYND domain containing 3 | -0.0195234 |
| ETV1 | ets variant 1 | -0.019454 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0194331 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0193152 |
| MAP4 | microtubule-associated protein 4 | -0.01923 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0190787 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0188901 |
