| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.167488 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.072019 |
| PCBP2 | poly(rC) binding protein 2 | 0.0611877 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0608745 |
| FTL | ferritin, light polypeptide | 0.0606659 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0515541 |
| RPS12 | ribosomal protein S12 | 0.0479456 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0430934 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0415834 |
| RPS3 | ribosomal protein S3 | 0.0363835 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0341356 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0332406 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0328648 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0325201 |
| CLDN4 | claudin 4 | 0.0323955 |
| RCOR1 | REST corepressor 1 | 0.0322205 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0317051 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0307075 |
| MYO1E | myosin IE | 0.0298816 |
| BRD2 | bromodomain containing 2 | 0.0296282 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0289091 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0279909 |
| RPL37A | ribosomal protein L37a | 0.0278289 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0276075 |
| RPS17 | ribosomal protein S17 | 0.0274674 |
| ADM | adrenomedullin | 0.0272241 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0270557 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0265117 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0264661 |
| INTS6 | integrator complex subunit 6 | 0.0259681 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0258293 |
| CTBP2 | C-terminal binding protein 2 | 0.0256344 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0250355 |
| RPS2 | ribosomal protein S2 | 0.0248456 |
| TMF1 | TATA element modulatory factor 1 | 0.0241196 |
| NEBL | nebulette | 0.0240866 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.02382 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0235948 |
| DIAPH1 | diaphanous-related formin 1 | 0.0230232 |
| PNN | pinin, desmosome associated protein | 0.0230092 |
| YAP1 | Yes-associated protein 1 | 0.0229124 |
| VEGFA | vascular endothelial growth factor A | 0.0228708 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0226293 |
| RPL35A | ribosomal protein L35a | 0.0220564 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0220295 |
| TJP1 | tight junction protein 1 | 0.0220209 |
| FLNA | filamin A, alpha | 0.0219875 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0216873 |
| ATF4 | activating transcription factor 4 | 0.0214608 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0212996 |
| CCNL1 | cyclin L1 | 0.0212922 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0211378 |
| B2M | beta-2-microglobulin | 0.0210191 |
| TXNIP | thioredoxin interacting protein | 0.0208956 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0208555 |
| RPL3 | ribosomal protein L3 | 0.0207924 |
| SET | SET nuclear proto-oncogene | 0.0207402 |
| SSRP1 | structure specific recognition protein 1 | 0.0206399 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0202807 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0201532 |
| DSPP | dentin sialophosphoprotein | 0.0201281 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0200867 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.020033 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0200127 |
| SMAD3 | SMAD family member 3 | 0.019602 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0195944 |
| ZFP36 | ZFP36 ring finger protein | 0.0192568 |
| ETV6 | ets variant 6 | 0.0191475 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0190483 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0188729 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0188306 |
| SFTPA2 | surfactant protein A2 | 0.0187783 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.018502 |
| MALT1 | MALT1 paracaspase | 0.0183479 |
| CUL3 | cullin 3 | 0.0183098 |
| PCDH1 | protocadherin 1 | 0.0181527 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0179961 |
| EGFR | epidermal growth factor receptor | 0.0178736 |
| STC2 | stanniocalcin 2 | 0.017592 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0173479 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0173205 |
| CCNY | cyclin Y | 0.0172306 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0170063 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0167808 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0167448 |
| RPS6 | ribosomal protein S6 | 0.0167143 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0165596 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0164852 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0163909 |
| WLS | wntless Wnt ligand secretion mediator | 0.0163516 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0163477 |
| ACTN1 | actinin, alpha 1 | 0.0161146 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0160547 |
| RPL9 | ribosomal protein L9 | 0.0160223 |
| HKDC1 | hexokinase domain containing 1 | 0.0159826 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0159146 |
| NDRG1 | N-myc downstream regulated 1 | 0.0156587 |
| HDGF | hepatoma-derived growth factor | 0.0156232 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0156035 |
| FAM13B | family with sequence similarity 13, member B | 0.0154342 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.166094 |
| PTMA | prothymosin, alpha | -0.127216 |
| KRT8 | keratin 8, type II | -0.119329 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.109843 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.104164 |
| TMEM123 | transmembrane protein 123 | -0.0959696 |
| KRT18 | keratin 18, type I | -0.088961 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0883061 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0855134 |
| IER3 | immediate early response 3 | -0.0704574 |
| ACTN4 | actinin, alpha 4 | -0.0701102 |
| GNAS | GNAS complex locus | -0.0679781 |
| CCND1 | cyclin D1 | -0.0663422 |
| ANXA2 | annexin A2 | -0.0662197 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0649089 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0594175 |
| H1-0 | H1.0 linker histone | -0.0591777 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0572925 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0572809 |
| TMSB10 | thymosin beta 10 | -0.0532252 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.052179 |
| S100A10 | S100 calcium binding protein A10 | -0.0517653 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0512532 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0501358 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0484407 |
| SDC4 | syndecan 4 | -0.0457427 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0443607 |
| RHEB | Ras homolog enriched in brain | -0.0426606 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0418149 |
| ACTG1 | actin gamma 1 | -0.041727 |
| AHNAK | AHNAK nucleoprotein | -0.040245 |
| PERP | PERP, TP53 apoptosis effector | -0.0391547 |
| RPL32 | ribosomal protein L32 | -0.0377084 |
| RPS21 | ribosomal protein S21 | -0.0376926 |
| HDLBP | high density lipoprotein binding protein | -0.0372164 |
| ARF1 | ADP-ribosylation factor 1 | -0.0370417 |
| S100A6 | S100 calcium binding protein A6 | -0.0366955 |
| SNX9 | sorting nexin 9 | -0.036611 |
| SQSTM1 | sequestosome 1 | -0.0361123 |
| SERINC5 | serine incorporator 5 | -0.0358588 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0354482 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0352668 |
| CANX | calnexin | -0.0351996 |
| RPS24 | ribosomal protein S24 | -0.0351141 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0340793 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0337499 |
| RPL8 | ribosomal protein L8 | -0.0333084 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0331622 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0331531 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0330903 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0328582 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0326045 |
| ZFR | zinc finger RNA binding protein | -0.0324485 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0319674 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0315597 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0315432 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0311091 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0308514 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0306614 |
| ZNF217 | zinc finger protein 217 | -0.0295955 |
| UBC | ubiquitin C | -0.0295567 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0294556 |
| RPLP1 | ribosomal protein, large, P1 | -0.0293488 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0292985 |
| CDCP1 | CUB domain containing protein 1 | -0.0289411 |
| TPX2 | TPX2, microtubule-associated | -0.0284728 |
| USP3 | ubiquitin specific peptidase 3 | -0.0279692 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.02773 |
| FAM3C | family with sequence similarity 3, member C | -0.027288 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.027069 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0269437 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0269064 |
| SEPTIN7 | septin 7 | -0.0268901 |
| DEK | DEK proto-oncogene | -0.0268181 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0266742 |
| KPNB1 | karyopherin (importin) beta 1 | -0.026582 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0265765 |
| JMJD1C | jumonji domain containing 1C | -0.0265658 |
| FRMD5 | FERM domain containing 5 | -0.0264955 |
| RPL4 | ribosomal protein L4 | -0.0261843 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0260449 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0258359 |
| ADNP | activity-dependent neuroprotector homeobox | -0.02566 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0253716 |
| NF1 | neurofibromin 1 | -0.0252591 |
| RPL27A | ribosomal protein L27a | -0.0251752 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0250504 |
| ITGB4 | integrin, beta 4 | -0.0247188 |
| CTSD | cathepsin D | -0.0246595 |
| TUBB | tubulin, beta class I | -0.024408 |
| EHBP1 | EH domain binding protein 1 | -0.0243809 |
| DSG2 | desmoglein 2 | -0.0241863 |
| ZNF292 | zinc finger protein 292 | -0.0240662 |
| RPLP0 | ribosomal protein, large, P0 | -0.0237691 |
| MATR3 | matrin 3 | -0.0237536 |
| HMGB2 | high mobility group box 2 | -0.0232459 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0232273 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0232142 |
| RYBP | RING1 and YY1 binding protein | -0.0230572 |
| MAP4 | microtubule-associated protein 4 | -0.023027 |
