| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.0851939 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0841256 |
| ATXN1 | ataxin 1 | 0.0532945 |
| RPS12 | ribosomal protein S12 | 0.0496269 |
| LAMB3 | laminin, beta 3 | 0.0430603 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0422183 |
| RPS17 | ribosomal protein S17 | 0.0361352 |
| YAP1 | Yes-associated protein 1 | 0.0340917 |
| RPL31 | ribosomal protein L31 | 0.0323886 |
| CPOX | coproporphyrinogen oxidase | 0.0313307 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0295485 |
| EFNB2 | ephrin-B2 | 0.0285311 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0283088 |
| IGSF9B | immunoglobulin superfamily, member 9B | 0.027674 |
| SGMS2 | sphingomyelin synthase 2 | 0.0263582 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0240351 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0240101 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0237772 |
| RPS3 | ribosomal protein S3 | 0.0226097 |
| RPL26 | ribosomal protein L26 | 0.0224228 |
| WWOX | WW domain containing oxidoreductase | 0.022406 |
| RPS4X | ribosomal protein S4, X-linked | 0.0222035 |
| ANXA1 | annexin A1 | 0.0221601 |
| MYO5B | myosin VB | 0.0215438 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0214218 |
| ATL2 | atlastin GTPase 2 | 0.0214098 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0207815 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0205414 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0205281 |
| RRM2 | ribonucleotide reductase M2 | 0.0199332 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0197449 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0197125 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0196298 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0193877 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0193861 |
| SLC30A10 | solute carrier family 30, member 10 | 0.0192808 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0189959 |
| SEPTIN9 | septin 9 | 0.0185812 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0185174 |
| SMAD3 | SMAD family member 3 | 0.0182921 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0181763 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0180305 |
| RPL9 | ribosomal protein L9 | 0.0178974 |
| HELLS | helicase, lymphoid-specific | 0.0178823 |
| KLF6 | Kruppel-like factor 6 | 0.0177607 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0168667 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0167348 |
| RPS3A | ribosomal protein S3A | 0.016731 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0166428 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.01658 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0165246 |
| MT2A | metallothionein 2A | 0.0165054 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0164004 |
| DST | dystonin | 0.0161848 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0160513 |
| INTS6 | integrator complex subunit 6 | 0.0157937 |
| BMS1 | BMS1 ribosome biogenesis factor | 0.0157273 |
| RBM39 | RNA binding motif protein 39 | 0.0156536 |
| NAV2 | neuron navigator 2 | 0.0155799 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0154939 |
| HOMER1 | homer scaffolding protein 1 | 0.014985 |
| CMIP | c-Maf inducing protein | 0.0144251 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0143252 |
| RPS7 | ribosomal protein S7 | 0.0143203 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0142667 |
| FN1 | fibronectin 1 | 0.0141277 |
| TXNIP | thioredoxin interacting protein | 0.0139812 |
| RPS19 | ribosomal protein S19 | 0.013938 |
| FHL2 | four and a half LIM domains 2 | 0.0139321 |
| RPS27A | ribosomal protein S27a | 0.0138369 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0138173 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0137561 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0137035 |
| RPL27 | ribosomal protein L27 | 0.0136222 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.013542 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0135188 |
| GPC6 | glypican 6 | 0.0133848 |
| ZNF407 | zinc finger protein 407 | 0.0133671 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0133558 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | 0.0132192 |
| IL18 | interleukin 18 | 0.0131502 |
| IRS2 | insulin receptor substrate 2 | 0.0131426 |
| PRELID2 | PRELI domain containing 2 | 0.0131218 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.013095 |
| PDE10A | phosphodiesterase 10A | 0.0130608 |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F | 0.0130307 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0130201 |
| CLDN4 | claudin 4 | 0.0129746 |
| MIDN | midnolin | 0.0129685 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0129444 |
| DENR | density-regulated protein | 0.0129051 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0128902 |
| CEP350 | centrosomal protein 350kDa | 0.0127321 |
| SVIL | supervillin | 0.0125644 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.0125457 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0125036 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0123396 |
| NFIB | nuclear factor I/B | 0.0122291 |
| SETX | senataxin | 0.0122081 |
| ADM | adrenomedullin | 0.0121507 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.200158 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.193045 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.157431 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.111363 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.109138 |
| ACTG1 | actin gamma 1 | -0.105927 |
| RPS6 | ribosomal protein S6 | -0.101057 |
| IER3 | immediate early response 3 | -0.0832828 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0743063 |
| FERMT1 | fermitin family member 1 | -0.0740126 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0675801 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0631336 |
| EZR | ezrin | -0.0599144 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0544334 |
| RPLP1 | ribosomal protein, large, P1 | -0.0525156 |
| S100A10 | S100 calcium binding protein A10 | -0.0501897 |
| LDHA | lactate dehydrogenase A | -0.0496408 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0487928 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0483686 |
| GPHN | gephyrin | -0.0468135 |
| OXR1 | oxidation resistance 1 | -0.0464943 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0461176 |
| HDAC2 | histone deacetylase 2 | -0.0451522 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0431026 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.042667 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0421099 |
| PKM | pyruvate kinase, muscle | -0.0418263 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.0415146 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.041251 |
| LMO7 | LIM domain 7 | -0.0408423 |
| RPL4 | ribosomal protein L4 | -0.0394214 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0388667 |
| VCL | vinculin | -0.0388569 |
| S100A6 | S100 calcium binding protein A6 | -0.0383203 |
| RPL34 | ribosomal protein L34 | -0.0381786 |
| TPM4 | tropomyosin 4 | -0.0381146 |
| EHBP1 | EH domain binding protein 1 | -0.0377554 |
| RPS8 | ribosomal protein S8 | -0.0377266 |
| CUX1 | cut-like homeobox 1 | -0.0372988 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0371535 |
| RPS29 | ribosomal protein S29 | -0.0366224 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0365231 |
| GDF15 | growth differentiation factor 15 | -0.0356926 |
| KPNB1 | karyopherin (importin) beta 1 | -0.03499 |
| RPLP0 | ribosomal protein, large, P0 | -0.0346812 |
| GLG1 | golgi glycoprotein 1 | -0.0342388 |
| HMGA2 | high mobility group AT-hook 2 | -0.0339178 |
| HMGA1 | high mobility group AT-hook 1 | -0.0339029 |
| GOLGA4 | golgin A4 | -0.0333908 |
| FOSL1 | FOS-like antigen 1 | -0.0333112 |
| MTAP | methylthioadenosine phosphorylase | -0.0326952 |
| RUNX2 | runt-related transcription factor 2 | -0.0325458 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0322401 |
| TXNRD1 | thioredoxin reductase 1 | -0.0318846 |
| RAD51B | RAD51 paralog B | -0.0317491 |
| NF1 | neurofibromin 1 | -0.0310909 |
| DEK | DEK proto-oncogene | -0.0310289 |
| NEK7 | NIMA-related kinase 7 | -0.0310191 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0308004 |
| CD9 | CD9 molecule | -0.0306988 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0304621 |
| NDRG1 | N-myc downstream regulated 1 | -0.0304428 |
| RPL5 | ribosomal protein L5 | -0.0300061 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0297383 |
| SQSTM1 | sequestosome 1 | -0.0294526 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0291099 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0288372 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0287794 |
| TMEM123 | transmembrane protein 123 | -0.0284973 |
| AOPEP | aminopeptidase O (putative) | -0.0280126 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0278438 |
| RPL8 | ribosomal protein L8 | -0.0272907 |
| TMSB10 | thymosin beta 10 | -0.0271395 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.026687 |
| RPS5 | ribosomal protein S5 | -0.0265492 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0265316 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.02624 |
| FLOT1 | flotillin 1 | -0.0261613 |
| BMP4 | bone morphogenetic protein 4 | -0.0260052 |
| EREG | epiregulin | -0.0258974 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.025885 |
| ACTN4 | actinin, alpha 4 | -0.0258703 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0256826 |
| RPL28 | ribosomal protein L28 | -0.025524 |
| RPS23 | ribosomal protein S23 | -0.0255043 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0252982 |
| MKI67 | marker of proliferation Ki-67 | -0.0250996 |
| RBM6 | RNA binding motif protein 6 | -0.024823 |
| FAT1 | FAT atypical cadherin 1 | -0.0248117 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0246655 |
| TOP1 | topoisomerase (DNA) I | -0.0246468 |
| ITGB4 | integrin, beta 4 | -0.0244015 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0243667 |
| ZFR | zinc finger RNA binding protein | -0.0243228 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0243096 |
| RPL32 | ribosomal protein L32 | -0.023972 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0238712 |
| EXOC4 | exocyst complex component 4 | -0.0238473 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0237633 |
| COG5 | component of oligomeric golgi complex 5 | -0.0236661 |
