| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.199623 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.189777 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0701489 |
| WWOX | WW domain containing oxidoreductase | 0.0683266 |
| PTMA | prothymosin, alpha | 0.0653221 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0635936 |
| RPS12 | ribosomal protein S12 | 0.0630464 |
| RPL26 | ribosomal protein L26 | 0.0535626 |
| RPS3 | ribosomal protein S3 | 0.0518544 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0511866 |
| PCBP2 | poly(rC) binding protein 2 | 0.0509387 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0481041 |
| DSPP | dentin sialophosphoprotein | 0.0477048 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0459311 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0450653 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0440264 |
| MT2A | metallothionein 2A | 0.0429493 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0429449 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0401031 |
| RPL37A | ribosomal protein L37a | 0.0396684 |
| ACTN1 | actinin, alpha 1 | 0.0394974 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0384546 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.03714 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0362286 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0361328 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0343902 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0334914 |
| RPS2 | ribosomal protein S2 | 0.0332636 |
| SET | SET nuclear proto-oncogene | 0.0325316 |
| LMO7 | LIM domain 7 | 0.0325268 |
| RPS19 | ribosomal protein S19 | 0.0312428 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0306951 |
| SON | SON DNA binding protein | 0.0306711 |
| EFNB2 | ephrin-B2 | 0.0303581 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0299729 |
| RPS17 | ribosomal protein S17 | 0.0293523 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0286028 |
| ASPH | aspartate beta-hydroxylase | 0.0285208 |
| RPL9 | ribosomal protein L9 | 0.0283825 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0283228 |
| YAP1 | Yes-associated protein 1 | 0.0279416 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0277737 |
| SMAD3 | SMAD family member 3 | 0.0274893 |
| MSN | moesin | 0.0274581 |
| ZNF638 | zinc finger protein 638 | 0.0274104 |
| FLNA | filamin A, alpha | 0.0273872 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0267094 |
| PNN | pinin, desmosome associated protein | 0.0265924 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0265813 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0265607 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0265217 |
| BMP5 | bone morphogenetic protein 5 | 0.0262634 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0261117 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0256686 |
| FAT1 | FAT atypical cadherin 1 | 0.0255925 |
| RPL3 | ribosomal protein L3 | 0.0254608 |
| AXIN2 | axin 2 | 0.0252529 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0251657 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0246586 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.024544 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0241962 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0237792 |
| SYT1 | synaptotagmin I | 0.0235411 |
| PRELID2 | PRELI domain containing 2 | 0.0234374 |
| PLEC | plectin | 0.0233345 |
| IRS2 | insulin receptor substrate 2 | 0.0232133 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0232015 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0231539 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0230474 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0228728 |
| RPS4X | ribosomal protein S4, X-linked | 0.0228339 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0224177 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0217756 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0215169 |
| RPL35A | ribosomal protein L35a | 0.0212288 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0211763 |
| MCC | mutated in colorectal cancers | 0.0209956 |
| ENO1 | enolase 1, (alpha) | 0.0209562 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0205279 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.02051 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0204716 |
| RPS7 | ribosomal protein S7 | 0.0204354 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.020331 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0202696 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0201107 |
| TNS3 | tensin 3 | 0.0200775 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0197217 |
| MSI2 | musashi RNA-binding protein 2 | 0.0196522 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.019642 |
| DIAPH1 | diaphanous-related formin 1 | 0.0195205 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0194895 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 0.0194339 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0193805 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 0.019327 |
| AATF | apoptosis antagonizing transcription factor | 0.0190975 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0189539 |
| ZNRF3 | zinc and ring finger 3 | 0.0189246 |
| PCM1 | pericentriolar material 1 | 0.0184922 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0184762 |
| RPS18 | ribosomal protein S18 | 0.0184753 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.323381 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.123634 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.115936 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0950836 |
| KRT8 | keratin 8, type II | -0.0931179 |
| VCL | vinculin | -0.0896368 |
| ACTG1 | actin gamma 1 | -0.0826919 |
| ANXA2 | annexin A2 | -0.077116 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0722544 |
| TMEM123 | transmembrane protein 123 | -0.0706552 |
| CDH13 | cadherin 13 | -0.0698565 |
| CCND1 | cyclin D1 | -0.0647514 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0639415 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0634093 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0560085 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0536215 |
| PERP | PERP, TP53 apoptosis effector | -0.0535957 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0522564 |
| GLG1 | golgi glycoprotein 1 | -0.0513921 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0502861 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0498151 |
| KRT18 | keratin 18, type I | -0.0497771 |
| TPM4 | tropomyosin 4 | -0.049075 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.046679 |
| MORF4L2 | mortality factor 4 like 2 | -0.0436735 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0436734 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0432926 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0428519 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0427055 |
| S100A10 | S100 calcium binding protein A10 | -0.0426635 |
| USP34 | ubiquitin specific peptidase 34 | -0.0418691 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0415886 |
| GNAS | GNAS complex locus | -0.0405389 |
| EGR1 | early growth response 1 | -0.0403221 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0387412 |
| ITGB4 | integrin, beta 4 | -0.0384341 |
| AHNAK | AHNAK nucleoprotein | -0.0381156 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0376667 |
| WASF2 | WAS protein family, member 2 | -0.0371368 |
| RPS25 | ribosomal protein S25 | -0.0371282 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0370173 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0367008 |
| RPS24 | ribosomal protein S24 | -0.0365034 |
| ARF4 | ADP-ribosylation factor 4 | -0.0362791 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0354714 |
| RPLP0 | ribosomal protein, large, P0 | -0.0354591 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0349773 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0349242 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0346242 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0342692 |
| RPS6 | ribosomal protein S6 | -0.0337115 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.033313 |
| SBF2 | SET binding factor 2 | -0.0332533 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0328932 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.032869 |
| RTN3 | reticulon 3 | -0.0328612 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0324189 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0315199 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0315173 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.031274 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0312095 |
| TMEM41B | transmembrane protein 41B | -0.0309765 |
| NF1 | neurofibromin 1 | -0.0305538 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0300108 |
| RPL27A | ribosomal protein L27a | -0.0296777 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.029601 |
| RPS5 | ribosomal protein S5 | -0.0292144 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0290128 |
| RBMX | RNA binding motif protein, X-linked | -0.0286501 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0283486 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.028267 |
| COG5 | component of oligomeric golgi complex 5 | -0.0279662 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0279499 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0277848 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0275784 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0275581 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0274821 |
| ATXN1 | ataxin 1 | -0.0274708 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0274118 |
| OLA1 | Obg-like ATPase 1 | -0.0272055 |
| JMJD1C | jumonji domain containing 1C | -0.0271096 |
| EZR | ezrin | -0.0270877 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0269654 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0266802 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0265881 |
| ANLN | anillin, actin binding protein | -0.0263343 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0262964 |
| HM13 | histocompatibility (minor) 13 | -0.026295 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0262442 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0262008 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0261625 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0261514 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0260843 |
| RPL39 | ribosomal protein L39 | -0.0260512 |
| RPL4 | ribosomal protein L4 | -0.0259971 |
| KRT19 | keratin 19, type I | -0.0259161 |
| RPL6 | ribosomal protein L6 | -0.0258865 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0256748 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0254151 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0251701 |
