| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.229089 |
| B2M | beta-2-microglobulin | 0.139042 |
| TMSB10 | thymosin beta 10 | 0.135127 |
| INHBA | inhibin, beta A | 0.122449 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.120869 |
| HLA-B | major histocompatibility complex, class I, B | 0.12073 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0920021 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0910167 |
| MT2A | metallothionein 2A | 0.0905519 |
| STC1 | stanniocalcin 1 | 0.0869062 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0823364 |
| RPS12 | ribosomal protein S12 | 0.0791947 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0744292 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0734661 |
| FTL | ferritin, light polypeptide | 0.0733601 |
| CD44 | CD44 molecule (Indian blood group) | 0.0690083 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0676029 |
| RPS8 | ribosomal protein S8 | 0.0658561 |
| RPL37A | ribosomal protein L37a | 0.0650829 |
| RPL35A | ribosomal protein L35a | 0.0602688 |
| NDRG1 | N-myc downstream regulated 1 | 0.0599076 |
| FN1 | fibronectin 1 | 0.0586854 |
| RPS3 | ribosomal protein S3 | 0.0582907 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0578936 |
| RPS6 | ribosomal protein S6 | 0.0574864 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0558351 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0550949 |
| RPL12 | ribosomal protein L12 | 0.0519432 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0505752 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0504137 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0500221 |
| RPL23 | ribosomal protein L23 | 0.0500029 |
| HLA-A | major histocompatibility complex, class I, A | 0.049463 |
| PTMA | prothymosin, alpha | 0.0483569 |
| RPS27A | ribosomal protein S27a | 0.0468956 |
| RACK1 | receptor for activated C kinase 1 | 0.046881 |
| ENO1 | enolase 1, (alpha) | 0.0464285 |
| RPL9 | ribosomal protein L9 | 0.0453177 |
| CALR | calreticulin | 0.0451515 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0451374 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0451333 |
| RPLP1 | ribosomal protein, large, P1 | 0.0448805 |
| RPS19 | ribosomal protein S19 | 0.0445711 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0443192 |
| RPL26 | ribosomal protein L26 | 0.0430587 |
| RPL11 | ribosomal protein L11 | 0.0408415 |
| RPS17 | ribosomal protein S17 | 0.0404572 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0403623 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0391612 |
| RPL31 | ribosomal protein L31 | 0.0386764 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.038324 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0379198 |
| FMNL2 | formin-like 2 | 0.0370032 |
| LDHA | lactate dehydrogenase A | 0.0350664 |
| TPI1 | triosephosphate isomerase 1 | 0.0350497 |
| TMSB4X | thymosin beta 4, X-linked | 0.0349757 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0342929 |
| RPS14 | ribosomal protein S14 | 0.0334359 |
| RPL37 | ribosomal protein L37 | 0.0332507 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0331596 |
| PCBP2 | poly(rC) binding protein 2 | 0.0331159 |
| ADM | adrenomedullin | 0.0330888 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0330345 |
| SFTPA2 | surfactant protein A2 | 0.0324874 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0322738 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0322207 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0308706 |
| RPL27 | ribosomal protein L27 | 0.0304135 |
| RPL5 | ribosomal protein L5 | 0.0299022 |
| VEGFA | vascular endothelial growth factor A | 0.0291728 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0291446 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0287573 |
| RPLP0 | ribosomal protein, large, P0 | 0.02864 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0286126 |
| ASPH | aspartate beta-hydroxylase | 0.0284014 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0282369 |
| RPL34 | ribosomal protein L34 | 0.0279358 |
| ATF4 | activating transcription factor 4 | 0.0277898 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0276579 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0274285 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0273603 |
| PGK1 | phosphoglycerate kinase 1 | 0.0272024 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.027103 |
| RPLP2 | ribosomal protein, large, P2 | 0.027048 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0264794 |
| RPL19 | ribosomal protein L19 | 0.0262094 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0254932 |
| RPS13 | ribosomal protein S13 | 0.0252746 |
| PRELID2 | PRELI domain containing 2 | 0.0252531 |
| CANX | calnexin | 0.0251277 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0242845 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0238008 |
| HDAC9 | histone deacetylase 9 | 0.0236473 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0232405 |
| RPS4X | ribosomal protein S4, X-linked | 0.0230979 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0229962 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0229828 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0229343 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0227752 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0225929 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MMP1 | matrix metallopeptidase 1 | -0.161379 |
| COL6A3 | collagen, type VI, alpha 3 | -0.107101 |
| EMP1 | epithelial membrane protein 1 | -0.0713131 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.050766 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0499551 |
| OXR1 | oxidation resistance 1 | -0.0463271 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0376936 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0370367 |
| SEPTIN11 | septin 11 | -0.0357914 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0350025 |
| COL1A1 | collagen, type I, alpha 1 | -0.0330391 |
| CAVIN1 | caveolae associated protein 1 | -0.0293984 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0278664 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0276309 |
| FRMD4A | FERM domain containing 4A | -0.0254722 |
| OSMR | oncostatin M receptor | -0.024769 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0247631 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0232584 |
| RAI14 | retinoic acid induced 14 | -0.0230835 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0227991 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0221993 |
| DIAPH2 | diaphanous-related formin 2 | -0.0221386 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0211804 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0210197 |
| SASH1 | SAM and SH3 domain containing 1 | -0.019361 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.018279 |
| KIAA1549L | KIAA1549-like | -0.0180286 |
| ATP13A3 | ATPase type 13A3 | -0.0179004 |
| FBN1 | fibrillin 1 | -0.0177914 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0176608 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -0.0174008 |
| VCAN | versican | -0.0172362 |
| HMGA2 | high mobility group AT-hook 2 | -0.0169586 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0167297 |
| HAS2 | hyaluronan synthase 2 | -0.0167198 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0163809 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0163155 |
| CCDC102B | coiled-coil domain containing 102B | -0.0162834 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0158694 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0153402 |
| PRRX1 | paired related homeobox 1 | -0.0152408 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0141225 |
| NAV1 | neuron navigator 1 | -0.0138996 |
| HDLBP | high density lipoprotein binding protein | -0.0138385 |
| LOX | lysyl oxidase | -0.0136876 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0136834 |
| COL3A1 | collagen, type III, alpha 1 | -0.0134126 |
| RASAL2 | RAS protein activator like 2 | -0.0133073 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0132683 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0131272 |
| CHSY3 | chondroitin sulfate synthase 3 | -0.0127103 |
| SOCS5 | suppressor of cytokine signaling 5 | -0.0119619 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0119247 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.0118354 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | -0.0118303 |
| MAP4 | microtubule-associated protein 4 | -0.0117861 |
| GLI2 | GLI family zinc finger 2 | -0.0117853 |
| EHD2 | EH-domain containing 2 | -0.0116824 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0116057 |
| TSHZ3 | teashirt zinc finger homeobox 3 | -0.0115996 |
| EBF1 | early B-cell factor 1 | -0.0115798 |
| SNAI2 | snail family zinc finger 2 | -0.0115459 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0115262 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0115097 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.0113882 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0112749 |
| SEC24D | SEC24 family member D | -0.0112737 |
| CYTH3 | cytohesin 3 | -0.0112672 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0112341 |
| NID2 | nidogen 2 (osteonidogen) | -0.0111598 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0110136 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0109747 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0109587 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0108624 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0108067 |
| GLG1 | golgi glycoprotein 1 | -0.0107738 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0107093 |
| TMEM263 | transmembrane protein 263 | -0.0106685 |
| GOLT1B | golgi transport 1B | -0.010623 |
| AHNAK | AHNAK nucleoprotein | -0.010545 |
| CDK17 | cyclin-dependent kinase 17 | -0.010515 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0105063 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0103917 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0103833 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0103639 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0103539 |
| SBF2 | SET binding factor 2 | -0.0102844 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0101287 |
| USP3 | ubiquitin specific peptidase 3 | -0.0100456 |
| NOTCH3 | notch 3 | -0.0100213 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0099922 |
| COL1A2 | collagen, type I, alpha 2 | -0.00996936 |
| WDR26 | WD repeat domain 26 | -0.00991852 |
| MED13L | mediator complex subunit 13-like | -0.00979995 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.00979754 |
| COL6A1 | collagen, type VI, alpha 1 | -0.00976933 |
| DST | dystonin | -0.0095998 |
| RIN2 | Ras and Rab interactor 2 | -0.00952748 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.00949723 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | -0.00940238 |
