| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fluvoxamine_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KDM3A | lysine (K)-specific demethylase 3A | 0.0372394 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0320723 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0311853 |
| RPL3 | ribosomal protein L3 | 0.0247126 |
| ATP11A | ATPase, class VI, type 11A | 0.022011 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0209738 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.020251 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0201874 |
| ARRDC3 | arrestin domain containing 3 | 0.0198942 |
| MGAT4C | MGAT4 family, member C | 0.0189256 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0175733 |
| GASK1B | golgi associated kinase 1B | 0.0173862 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0171858 |
| YEATS2 | YEATS domain containing 2 | 0.0151723 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0145289 |
| PER1 | period circadian clock 1 | 0.0144396 |
| NCKAP1 | NCK-associated protein 1 | 0.014435 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0141276 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.013832 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0137272 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0136095 |
| OGA | O-GlcNAcase | 0.0129521 |
| KLHL24 | kelch-like family member 24 | 0.0128023 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0127383 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0127287 |
| ZNF292 | zinc finger protein 292 | 0.0126851 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0121639 |
| VPS8 | vacuolar protein sorting 8 homolog (S. cerevisiae) | 0.011607 |
| LEMD3 | LEM domain containing 3 | 0.0115947 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0114793 |
| CPOX | coproporphyrinogen oxidase | 0.0114594 |
| PLEC | plectin | 0.0114025 |
| ZNF217 | zinc finger protein 217 | 0.0113104 |
| FLNA | filamin A, alpha | 0.011003 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.010779 |
| CABIN1 | calcineurin binding protein 1 | 0.0107377 |
| AFDN | afadin, adherens junction formation factor | 0.0107214 |
| NBAS | neuroblastoma amplified sequence | 0.0105292 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0105081 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0104681 |
| KLC1 | kinesin light chain 1 | 0.0103697 |
| PCNX1 | pecanex 1 | 0.0103538 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0102944 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0102373 |
| CASC3 | cancer susceptibility candidate 3 | 0.0101157 |
| CDK19 | cyclin-dependent kinase 19 | 0.00995492 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.00958624 |
| EPHA6 | EPH receptor A6 | 0.00956601 |
| SNX13 | sorting nexin 13 | 0.00945391 |
| RHBDD1 | rhomboid domain containing 1 | 0.00944863 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00936815 |
| NUP58 | nucleoporin 58 | 0.00928835 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.00906834 |
| CEP95 | centrosomal protein 95kDa | 0.00895959 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.00895719 |
| MANBA | mannosidase, beta A, lysosomal | 0.00887585 |
| CCNG2 | cyclin G2 | 0.0088257 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.00872197 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0086667 |
| CTNNBL1 | catenin, beta like 1 | 0.0086552 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.00856796 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa | 0.00852999 |
| THOC1 | THO complex 1 | 0.00852326 |
| TFG | TRK-fused gene | 0.00842903 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.00832805 |
| CLDND1 | claudin domain containing 1 | 0.0083194 |
| DIPK2A | divergent protein kinase domain 2A | 0.00831471 |
| WDR41 | WD repeat domain 41 | 0.00830271 |
| TNRC6A | trinucleotide repeat containing 6A | 0.00827482 |
| SLC49A4 | solute carrier family 49 member 4 | 0.00821144 |
| DSCAM | Down syndrome cell adhesion molecule | 0.00820454 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.0081832 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.00815015 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.00813096 |
| RNF145 | ring finger protein 145 | 0.00810688 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.00808611 |
| PPP1R21 | protein phosphatase 1, regulatory subunit 21 | 0.00801067 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.00783402 |
| NONO | non-POU domain containing, octamer-binding | 0.00783356 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.00776112 |
| OCLN | occludin | 0.0077522 |
| PIK3R4 | phosphoinositide-3-kinase, regulatory subunit 4 | 0.00774711 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | 0.00772763 |
| ATRN | attractin | 0.0076918 |
| AXIN2 | axin 2 | 0.00766365 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00760289 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.00749611 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.00745342 |
| HSPA4 | heat shock 70kDa protein 4 | 0.00743271 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.00729435 |
| TSPAN9 | tetraspanin 9 | 0.00728903 |
| RPL4 | ribosomal protein L4 | 0.0072753 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.00726177 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.00721648 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.00718957 |
| TMEM39A | transmembrane protein 39A | 0.00715677 |
| SMYD3 | SET and MYND domain containing 3 | 0.00710637 |
| UBP1 | upstream binding protein 1 (LBP-1a) | 0.0071047 |
| COG5 | component of oligomeric golgi complex 5 | 0.00707468 |
| NUDCD3 | NudC domain containing 3 | 0.00706513 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.234282 |
| NLGN1 | neuroligin 1 | -0.21093 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.169986 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.165215 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.133001 |
| TMSB10 | thymosin beta 10 | -0.126443 |
| AREG | amphiregulin | -0.115828 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0759961 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0746164 |
| MMP12 | matrix metallopeptidase 12 | -0.069016 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0688212 |
| ANKRD12 | ankyrin repeat domain 12 | -0.068032 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0661662 |
| PTMA | prothymosin, alpha | -0.0619138 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0610595 |
| FTL | ferritin, light polypeptide | -0.059018 |
| ACTG1 | actin gamma 1 | -0.0579546 |
| PCDH7 | protocadherin 7 | -0.0573826 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.05649 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0549454 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0522873 |
| DST | dystonin | -0.0518755 |
| HMGA2 | high mobility group AT-hook 2 | -0.051021 |
| ANXA1 | annexin A1 | -0.049996 |
| RASAL2 | RAS protein activator like 2 | -0.0484136 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0480027 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0470238 |
| RPS6 | ribosomal protein S6 | -0.0467427 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0466683 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0458046 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0437045 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0432772 |
| ZNF804A | zinc finger protein 804A | -0.0428621 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0408953 |
| TUBA1B | tubulin, alpha 1b | -0.04051 |
| NHSL1 | NHS-like 1 | -0.0389452 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0379611 |
| MAP1B | microtubule-associated protein 1B | -0.0375756 |
| EHBP1 | EH domain binding protein 1 | -0.0375283 |
| YAP1 | Yes-associated protein 1 | -0.0373975 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0367274 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0356952 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0351613 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.034824 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0347801 |
| MKI67 | marker of proliferation Ki-67 | -0.0343925 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0337504 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0330518 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0327683 |
| PFN1 | profilin 1 | -0.0321371 |
| POTEF | POTE ankyrin domain family, member F | -0.0321352 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.031968 |
| CCND1 | cyclin D1 | -0.0318282 |
| RTN4 | reticulon 4 | -0.0311479 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0306538 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0306407 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0306068 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0304777 |
| TPI1 | triosephosphate isomerase 1 | -0.0302813 |
| ENO1 | enolase 1, (alpha) | -0.0301234 |
| LMO7 | LIM domain 7 | -0.0300823 |
| RPLP0 | ribosomal protein, large, P0 | -0.0299669 |
| RPLP1 | ribosomal protein, large, P1 | -0.0297705 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0296229 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0295781 |
| RPS8 | ribosomal protein S8 | -0.0292341 |
| EGR1 | early growth response 1 | -0.0291719 |
| HMGA1 | high mobility group AT-hook 1 | -0.0291085 |
| ASPH | aspartate beta-hydroxylase | -0.0290751 |
| RPL35A | ribosomal protein L35a | -0.0288837 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0285672 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0284452 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0282224 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0277252 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0277025 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0274194 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0267859 |
| CCN2 | cellular communication network factor 2 | -0.0264962 |
| VMP1 | vacuole membrane protein 1 | -0.0261599 |
| CENPF | centromere protein F, 350/400kDa | -0.0257993 |
| SYT1 | synaptotagmin I | -0.0255543 |
| RPL19 | ribosomal protein L19 | -0.0251639 |
| RPS27A | ribosomal protein S27a | -0.0251016 |
| CALR | calreticulin | -0.0250832 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0250777 |
| KPNB1 | karyopherin (importin) beta 1 | -0.024741 |
| CANX | calnexin | -0.0247251 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0244151 |
| RPL12 | ribosomal protein L12 | -0.0243813 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0241209 |
| RPS21 | ribosomal protein S21 | -0.0239743 |
| RPS19 | ribosomal protein S19 | -0.0238208 |
| BPTF | bromodomain PHD finger transcription factor | -0.0238038 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0237911 |
| LDHB | lactate dehydrogenase B | -0.0235189 |
| GNAS | GNAS complex locus | -0.0232962 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0232726 |
| ERBIN | erbb2 interacting protein | -0.0231661 |
| TMEM123 | transmembrane protein 123 | -0.0231624 |
| TENM3 | teneurin transmembrane protein 3 | -0.0230683 |
