| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.152234 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.119339 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.101358 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0969726 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0952689 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0843195 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0835178 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0725561 |
| ATXN1 | ataxin 1 | 0.0678848 |
| ASPH | aspartate beta-hydroxylase | 0.0665357 |
| AFDN | afadin, adherens junction formation factor | 0.0653094 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0636757 |
| TNS1 | tensin 1 | 0.0614701 |
| RPL3 | ribosomal protein L3 | 0.059076 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0571952 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0571261 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0566937 |
| DTNA | dystrobrevin, alpha | 0.0527102 |
| MSI2 | musashi RNA-binding protein 2 | 0.0517572 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0503202 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0490887 |
| SVIL | supervillin | 0.0462087 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0446796 |
| FMNL2 | formin-like 2 | 0.0433357 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0414 |
| NDRG1 | N-myc downstream regulated 1 | 0.0410726 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0409344 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.0401979 |
| PRELID2 | PRELI domain containing 2 | 0.0401228 |
| SMAD3 | SMAD family member 3 | 0.0398755 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0395177 |
| GSE1 | Gse1 coiled-coil protein | 0.039239 |
| KIAA1217 | KIAA1217 | 0.0392336 |
| FLNB | filamin B, beta | 0.038929 |
| PLEC | plectin | 0.0383048 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0380974 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0379667 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0366106 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0365695 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.036287 |
| MYO1B | myosin IB | 0.0360075 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0357855 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0350123 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0349129 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0341548 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.0341137 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.03401 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0339523 |
| CRLS1 | cardiolipin synthase 1 | 0.0337404 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0325773 |
| FLNA | filamin A, alpha | 0.032412 |
| PTK2 | protein tyrosine kinase 2 | 0.0320578 |
| ARFGEF3 | ARFGEF family member 3 | 0.0315831 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0314493 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0305662 |
| HLF | hepatic leukemia factor | 0.0296876 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.029682 |
| ZNF292 | zinc finger protein 292 | 0.0288386 |
| JAG1 | jagged 1 | 0.028615 |
| ANO6 | anoctamin 6 | 0.028447 |
| IL4R | interleukin 4 receptor | 0.0283986 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0283935 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0282865 |
| GPC6 | glypican 6 | 0.0281568 |
| VEGFA | vascular endothelial growth factor A | 0.0281058 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0278156 |
| DENND1A | DENN/MADD domain containing 1A | 0.0274812 |
| DIDO1 | death inducer-obliterator 1 | 0.0272257 |
| NGLY1 | N-glycanase 1 | 0.0270133 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0267613 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0264304 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0260637 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0260045 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.025807 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.025172 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0249559 |
| FBXO42 | F-box protein 42 | 0.0247678 |
| FN1 | fibronectin 1 | 0.0246946 |
| SBF2 | SET binding factor 2 | 0.0246422 |
| YEATS2 | YEATS domain containing 2 | 0.024623 |
| MTSS1 | metastasis suppressor 1 | 0.024556 |
| FNIP1 | folliculin interacting protein 1 | 0.0243082 |
| RELL1 | RELT-like 1 | 0.0234199 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0233674 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0233293 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0232806 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0229532 |
| KYNU | kynureninase | 0.0229476 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0226403 |
| FAT1 | FAT atypical cadherin 1 | 0.0224973 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0224086 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0223544 |
| PDE8A | phosphodiesterase 8A | 0.0222034 |
| USP47 | ubiquitin specific peptidase 47 | 0.0221727 |
| NCKAP1 | NCK-associated protein 1 | 0.0221477 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0220897 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.022082 |
| PLXDC2 | plexin domain containing 2 | 0.0217726 |
| FRK | fyn-related Src family tyrosine kinase | 0.0217167 |
| CHKA | choline kinase alpha | 0.0217047 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.247258 |
| APOB | apolipoprotein B | -0.154886 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.112788 |
| RPS6 | ribosomal protein S6 | -0.112532 |
| MT2A | metallothionein 2A | -0.106748 |
| FTL | ferritin, light polypeptide | -0.0893613 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0854148 |
| GPC3 | glypican 3 | -0.0787204 |
| RPL11 | ribosomal protein L11 | -0.0784343 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.07628 |
| TRIM26 | tripartite motif containing 26 | -0.0725851 |
| APOA2 | apolipoprotein A-II | -0.0695983 |
| RPLP1 | ribosomal protein, large, P1 | -0.0687564 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0674176 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0656241 |
| RPL37A | ribosomal protein L37a | -0.0636675 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0597654 |
| AHSG | alpha-2-HS-glycoprotein | -0.058611 |
| RPS8 | ribosomal protein S8 | -0.0577905 |
| RPS19 | ribosomal protein S19 | -0.0558997 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0531555 |
| RPS24 | ribosomal protein S24 | -0.0502369 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0487587 |
| APOA1 | apolipoprotein A-I | -0.0487041 |
| RPS27A | ribosomal protein S27a | -0.0485068 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0468109 |
| RPL34 | ribosomal protein L34 | -0.0467879 |
| RPL31 | ribosomal protein L31 | -0.0459884 |
| RPS12 | ribosomal protein S12 | -0.0454383 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0443868 |
| APOE | apolipoprotein E | -0.043174 |
| RPL12 | ribosomal protein L12 | -0.0430632 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0425441 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0423121 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0417706 |
| RPLP0 | ribosomal protein, large, P0 | -0.0412996 |
| CPE | carboxypeptidase E | -0.0411669 |
| RRBP1 | ribosome binding protein 1 | -0.0406698 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0401843 |
| RPL35A | ribosomal protein L35a | -0.0396368 |
| TF | transferrin | -0.0380335 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0374959 |
| RPS29 | ribosomal protein S29 | -0.0366122 |
| A2M | alpha-2-macroglobulin | -0.0360677 |
| RPLP2 | ribosomal protein, large, P2 | -0.0360179 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0358071 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0352408 |
| RPS23 | ribosomal protein S23 | -0.0348969 |
| CP | ceruloplasmin (ferroxidase) | -0.0347511 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0347298 |
| RPL23 | ribosomal protein L23 | -0.0346168 |
| RPL26 | ribosomal protein L26 | -0.034513 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0335669 |
| PEG10 | paternally expressed 10 | -0.0328828 |
| SELENOP | selenoprotein P | -0.0326904 |
| EGR1 | early growth response 1 | -0.0325593 |
| RPL19 | ribosomal protein L19 | -0.0325398 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0322014 |
| RPS14 | ribosomal protein S14 | -0.0310972 |
| GNAS | GNAS complex locus | -0.0310462 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0310336 |
| RPS3 | ribosomal protein S3 | -0.0309972 |
| RPL32 | ribosomal protein L32 | -0.0308347 |
| IER3 | immediate early response 3 | -0.0303814 |
| CANX | calnexin | -0.030147 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0300708 |
| RPL5 | ribosomal protein L5 | -0.0300137 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0299755 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0296889 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0294944 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0293791 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0292835 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.029261 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0287216 |
| PERP | PERP, TP53 apoptosis effector | -0.028466 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0284255 |
| PTMA | prothymosin, alpha | -0.028171 |
| RPS27 | ribosomal protein S27 | -0.0281005 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.0264981 |
| GDF15 | growth differentiation factor 15 | -0.0263196 |
| RACK1 | receptor for activated C kinase 1 | -0.0262832 |
| EHBP1 | EH domain binding protein 1 | -0.0259892 |
| RPL28 | ribosomal protein L28 | -0.0259672 |
| KIF5B | kinesin family member 5B | -0.0258084 |
| CST3 | cystatin C | -0.0253924 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0253861 |
| RBM25 | RNA binding motif protein 25 | -0.0250907 |
| LYZ | lysozyme | -0.0250863 |
| APOC1 | apolipoprotein C-I | -0.0249801 |
| RPL7A | ribosomal protein L7a | -0.0246343 |
| RPS16 | ribosomal protein S16 | -0.0245169 |
| STK17A | serine/threonine kinase 17a | -0.0244828 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -0.0243735 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0239803 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.023838 |
| RPL9 | ribosomal protein L9 | -0.0234102 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0232359 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0229847 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0229023 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0227278 |
