| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ATXN1 | ataxin 1 | 0.0734206 |
| PLEC | plectin | 0.0662716 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0653416 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0580643 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0552542 |
| KLHL29 | kelch-like family member 29 | 0.0517172 |
| HYOU1 | hypoxia up-regulated 1 | 0.0409486 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0400408 |
| FLNB | filamin B, beta | 0.0375025 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0355039 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0348099 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0338592 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0337413 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0336077 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.032738 |
| SMAD3 | SMAD family member 3 | 0.0324908 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0317824 |
| BCL2L1 | BCL2-like 1 | 0.031224 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0301563 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0300484 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0296881 |
| KIF16B | kinesin family member 16B | 0.029646 |
| PRELID2 | PRELI domain containing 2 | 0.0288954 |
| SEPTIN9 | septin 9 | 0.0287256 |
| NBAS | neuroblastoma amplified sequence | 0.0285864 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0282497 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0279668 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0279536 |
| ANXA11 | annexin A11 | 0.0277655 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0277486 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0277319 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0275166 |
| LMO7 | LIM domain 7 | 0.0274457 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0273658 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0269108 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0265008 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0256783 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0256393 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0251829 |
| PMM2 | phosphomannomutase 2 | 0.0251085 |
| CAPN8 | calpain 8 | 0.0247607 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0246986 |
| STK24 | serine/threonine kinase 24 | 0.0245661 |
| ATP11A | ATPase, class VI, type 11A | 0.0245093 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0243653 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0237639 |
| MYOF | myoferlin | 0.0224283 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0223304 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.022001 |
| CTBP2 | C-terminal binding protein 2 | 0.0219898 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0219845 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0217253 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0216954 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0216183 |
| ANKRD11 | ankyrin repeat domain 11 | 0.021305 |
| FNIP1 | folliculin interacting protein 1 | 0.0212059 |
| COG5 | component of oligomeric golgi complex 5 | 0.0211744 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0211149 |
| SEC24D | SEC24 family member D | 0.0210901 |
| TRIM2 | tripartite motif containing 2 | 0.020995 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0208911 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.020772 |
| TNRC18 | trinucleotide repeat containing 18 | 0.020752 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0206413 |
| SNX13 | sorting nexin 13 | 0.0205659 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0205563 |
| NDRG1 | N-myc downstream regulated 1 | 0.0202272 |
| VMP1 | vacuole membrane protein 1 | 0.0202083 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.020088 |
| CMIP | c-Maf inducing protein | 0.0200094 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.019963 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0197164 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0196602 |
| PGM3 | phosphoglucomutase 3 | 0.0192221 |
| FLNA | filamin A, alpha | 0.0191456 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0191189 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0189832 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0187843 |
| HELZ | helicase with zinc finger | 0.0185351 |
| ALPK1 | alpha-kinase 1 | 0.0185145 |
| COG6 | component of oligomeric golgi complex 6 | 0.0184827 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0183683 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0182709 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0181809 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0179879 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0179779 |
| EXOC6B | exocyst complex component 6B | 0.0178906 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0178487 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | 0.0178277 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0178164 |
| YEATS2 | YEATS domain containing 2 | 0.0177431 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0177232 |
| ZNF292 | zinc finger protein 292 | 0.0176277 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0175186 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0174477 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.017405 |
| TMEM39A | transmembrane protein 39A | 0.0173927 |
| AFDN | afadin, adherens junction formation factor | 0.017327 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 0.0172488 |
| YAP1 | Yes-associated protein 1 | 0.0169598 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.157135 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.155473 |
| PTMA | prothymosin, alpha | -0.1275 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.119059 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.117242 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.115508 |
| B2M | beta-2-microglobulin | -0.109309 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0871795 |
| S100A6 | S100 calcium binding protein A6 | -0.0831319 |
| FTL | ferritin, light polypeptide | -0.0744711 |
| RPS6 | ribosomal protein S6 | -0.074054 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0733774 |
| RPL35A | ribosomal protein L35a | -0.0727886 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0707292 |
| NPSR1 | neuropeptide S receptor 1 | -0.0704114 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0695772 |
| RPS3 | ribosomal protein S3 | -0.0691945 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0664423 |
| S100A10 | S100 calcium binding protein A10 | -0.0650999 |
| EPCAM | epithelial cell adhesion molecule | -0.0619911 |
| RPS19 | ribosomal protein S19 | -0.0590153 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0585015 |
| RPL23 | ribosomal protein L23 | -0.0576729 |
| KRT18 | keratin 18, type I | -0.0567079 |
| RPLP1 | ribosomal protein, large, P1 | -0.056299 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0558133 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0557636 |
| HLA-A | major histocompatibility complex, class I, A | -0.0536279 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0528672 |
| EMP1 | epithelial membrane protein 1 | -0.047998 |
| S100P | S100 calcium binding protein P | -0.0465753 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0447024 |
| CALR | calreticulin | -0.0446277 |
| RPL26 | ribosomal protein L26 | -0.0432109 |
| RPS8 | ribosomal protein S8 | -0.0431332 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0429415 |
| AREG | amphiregulin | -0.0424085 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0420852 |
| AGR2 | anterior gradient 2 | -0.0417021 |
| RPL19 | ribosomal protein L19 | -0.0415828 |
| H1-0 | H1.0 linker histone | -0.0413024 |
| PGK1 | phosphoglycerate kinase 1 | -0.0412915 |
| RPS25 | ribosomal protein S25 | -0.0409195 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0407012 |
| RPL12 | ribosomal protein L12 | -0.0406389 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0399654 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0399638 |
| S100A11 | S100 calcium binding protein A11 | -0.0395667 |
| RPL11 | ribosomal protein L11 | -0.0391892 |
| S100A9 | S100 calcium binding protein A9 | -0.037813 |
| ENO1 | enolase 1, (alpha) | -0.0373819 |
| HLA-B | major histocompatibility complex, class I, B | -0.0373277 |
| ATF5 | activating transcription factor 5 | -0.0369227 |
| RPL8 | ribosomal protein L8 | -0.036819 |
| HLA-E | major histocompatibility complex, class I, E | -0.0363633 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0362841 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0361714 |
| ACTG1 | actin gamma 1 | -0.0356579 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0356578 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0353736 |
| AGR3 | anterior gradient 3 | -0.0342778 |
| CBX3 | chromobox homolog 3 | -0.0341818 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0341735 |
| RPS21 | ribosomal protein S21 | -0.0341583 |
| MKI67 | marker of proliferation Ki-67 | -0.0340868 |
| DSTN | destrin (actin depolymerizing factor) | -0.0338872 |
| RPS24 | ribosomal protein S24 | -0.033848 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0335631 |
| KRT19 | keratin 19, type I | -0.0334115 |
| INSIG1 | insulin induced gene 1 | -0.0333372 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0328232 |
| RPL18 | ribosomal protein L18 | -0.0323975 |
| TMSB4X | thymosin beta 4, X-linked | -0.0320414 |
| RPL34 | ribosomal protein L34 | -0.0320053 |
| RPL37A | ribosomal protein L37a | -0.0317194 |
| H3-3B | H3.3 histone B | -0.0315522 |
| RRBP1 | ribosome binding protein 1 | -0.0311599 |
| RPS16 | ribosomal protein S16 | -0.0308196 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0301035 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0299832 |
| RPL28 | ribosomal protein L28 | -0.0299801 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0296914 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0294652 |
| RPL36A | ribosomal protein L36a | -0.0292865 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0290006 |
| DEK | DEK proto-oncogene | -0.0289995 |
| PKM | pyruvate kinase, muscle | -0.0289987 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0284642 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0282505 |
| HMGA1 | high mobility group AT-hook 1 | -0.028186 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0281263 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0280933 |
| RPLP0 | ribosomal protein, large, P0 | -0.0278823 |
| RPS27A | ribosomal protein S27a | -0.0278486 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0278126 |
| RPS12 | ribosomal protein S12 | -0.0276992 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0276956 |
| GNAS | GNAS complex locus | -0.0275783 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0275267 |
| CANX | calnexin | -0.0271103 |