| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fluvoxamine_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.184755 |
| NDRG1 | N-myc downstream regulated 1 | 0.141895 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.105705 |
| FAM13A | family with sequence similarity 13, member A | 0.0801421 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0726814 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0717268 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0676367 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.066166 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.065296 |
| FLNB | filamin B, beta | 0.0640988 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0603506 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0601769 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0597145 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0596533 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0588142 |
| VCL | vinculin | 0.0577105 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0570438 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0512125 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0483957 |
| ATXN1 | ataxin 1 | 0.0480033 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0472602 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0463648 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0462229 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0454188 |
| EXT1 | exostosin glycosyltransferase 1 | 0.045061 |
| CTBP2 | C-terminal binding protein 2 | 0.0448886 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0442165 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0428366 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.042819 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0423132 |
| RBM39 | RNA binding motif protein 39 | 0.0421598 |
| EREG | epiregulin | 0.0419104 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0414667 |
| CCNY | cyclin Y | 0.0409071 |
| MED13L | mediator complex subunit 13-like | 0.0402923 |
| SEC24D | SEC24 family member D | 0.0401357 |
| PRELID2 | PRELI domain containing 2 | 0.0396849 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0395243 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0389894 |
| PLEC | plectin | 0.0387656 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0384422 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0380061 |
| HDLBP | high density lipoprotein binding protein | 0.0377576 |
| ACTN4 | actinin, alpha 4 | 0.0372429 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0366443 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0360625 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0359249 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0358223 |
| RREB1 | ras responsive element binding protein 1 | 0.0353645 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0349902 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0347405 |
| SMYD3 | SET and MYND domain containing 3 | 0.0341107 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0340581 |
| RNF43 | ring finger protein 43 | 0.033981 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0339293 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0326876 |
| NEBL | nebulette | 0.0326265 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0324675 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.032432 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0319053 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0318555 |
| LMO7 | LIM domain 7 | 0.0314354 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0312858 |
| USP34 | ubiquitin specific peptidase 34 | 0.0306921 |
| GOLGA4 | golgin A4 | 0.0306556 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0305643 |
| MYO1E | myosin IE | 0.0305537 |
| NBAS | neuroblastoma amplified sequence | 0.0302473 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.030181 |
| COG5 | component of oligomeric golgi complex 5 | 0.030151 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0301439 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.029869 |
| OGA | O-GlcNAcase | 0.0294526 |
| WDR45B | WD repeat domain 45B | 0.0293933 |
| TFG | TRK-fused gene | 0.0288083 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0287214 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.028556 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0285159 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0283132 |
| COPA | coatomer protein complex, subunit alpha | 0.0282566 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0281173 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0279914 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0279691 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0279538 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0278974 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.027696 |
| VMP1 | vacuole membrane protein 1 | 0.0276021 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0270296 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0268832 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0267398 |
| USP53 | ubiquitin specific peptidase 53 | 0.0266559 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0263681 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0262829 |
| FAT1 | FAT atypical cadherin 1 | 0.0261465 |
| CALR | calreticulin | 0.0259236 |
| MYO5B | myosin VB | 0.0258138 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0257203 |
| FBXO11 | F-box protein 11 | 0.0256992 |
| HM13 | histocompatibility (minor) 13 | 0.0256026 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0254347 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.161432 |
| TMSB10 | thymosin beta 10 | -0.115561 |
| PTMA | prothymosin, alpha | -0.113154 |
| NPSR1 | neuropeptide S receptor 1 | -0.0849493 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0716935 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0630103 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0610806 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0605577 |
| RPS19 | ribosomal protein S19 | -0.0604015 |
| RPS6 | ribosomal protein S6 | -0.0590631 |
| KRT18 | keratin 18, type I | -0.0577671 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0568426 |
| S100A6 | S100 calcium binding protein A6 | -0.0527586 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0525275 |
| HMGA1 | high mobility group AT-hook 1 | -0.0481369 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0478013 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0467835 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0425497 |
| RPS12 | ribosomal protein S12 | -0.042107 |
| RPL18 | ribosomal protein L18 | -0.0410697 |
| RPL26 | ribosomal protein L26 | -0.0388501 |
| KRT19 | keratin 19, type I | -0.0379812 |
| LDHA | lactate dehydrogenase A | -0.036325 |
| RPL12 | ribosomal protein L12 | -0.0363191 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.034389 |
| RPL11 | ribosomal protein L11 | -0.0342178 |
| RPL23 | ribosomal protein L23 | -0.0340795 |
| S100P | S100 calcium binding protein P | -0.0340359 |
| YBX1 | Y box binding protein 1 | -0.0335276 |
| RPS3 | ribosomal protein S3 | -0.0330333 |
| H1-0 | H1.0 linker histone | -0.0329382 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0324313 |
| PFN1 | profilin 1 | -0.0323933 |
| FTL | ferritin, light polypeptide | -0.0323909 |
| RPLP0 | ribosomal protein, large, P0 | -0.0323807 |
| RBM25 | RNA binding motif protein 25 | -0.0316997 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0316584 |
| PERP | PERP, TP53 apoptosis effector | -0.0309075 |
| TPI1 | triosephosphate isomerase 1 | -0.0306734 |
| RPL36 | ribosomal protein L36 | -0.0300586 |
| RPL19 | ribosomal protein L19 | -0.0296387 |
| RPLP1 | ribosomal protein, large, P1 | -0.0290656 |
| RPL32 | ribosomal protein L32 | -0.0285795 |
| RPL7 | ribosomal protein L7 | -0.0281812 |
| CALB1 | calbindin 1, 28kDa | -0.0276886 |
| RPL5 | ribosomal protein L5 | -0.0275485 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0268782 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0268395 |
| POTEF | POTE ankyrin domain family, member F | -0.0266646 |
| CBX3 | chromobox homolog 3 | -0.0265726 |
| S100A14 | S100 calcium binding protein A14 | -0.0262787 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0262694 |
| KIF5B | kinesin family member 5B | -0.0262437 |
| RPL35 | ribosomal protein L35 | -0.0262138 |
| DSPP | dentin sialophosphoprotein | -0.0254023 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0251085 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.024932 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0248768 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0248267 |
| CADPS | Ca++-dependent secretion activator | -0.0243287 |
| RPL8 | ribosomal protein L8 | -0.0240947 |
| EHBP1 | EH domain binding protein 1 | -0.023737 |
| CENPF | centromere protein F, 350/400kDa | -0.0235491 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0231885 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0224713 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0222336 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.021959 |
| RACK1 | receptor for activated C kinase 1 | -0.0219343 |
| RPS2 | ribosomal protein S2 | -0.0218543 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0215775 |
| FOSL1 | FOS-like antigen 1 | -0.0214336 |
| EPCAM | epithelial cell adhesion molecule | -0.0213829 |
| B2M | beta-2-microglobulin | -0.02122 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0210801 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0207842 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0204523 |
| MUC17 | mucin 17, cell surface associated | -0.0202973 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0189497 |
| TNS4 | tensin 4 | -0.018839 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | -0.0188184 |
| CLDN7 | claudin 7 | -0.0187312 |
| MT2A | metallothionein 2A | -0.0186195 |
| HMGB1 | high mobility group box 1 | -0.0184013 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0183715 |
| RPL21 | ribosomal protein L21 | -0.0182143 |
| RPS5 | ribosomal protein S5 | -0.0181905 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0180413 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0180412 |
| EMP1 | epithelial membrane protein 1 | -0.0179908 |
| DSG2 | desmoglein 2 | -0.0179729 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0179336 |
| YBX3 | Y box binding protein 3 | -0.0178089 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0175555 |
| SON | SON DNA binding protein | -0.0174992 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0174023 |
| TAGLN2 | transgelin 2 | -0.0173861 |
| MT1X | metallothionein 1X | -0.0173618 |
| CCND1 | cyclin D1 | -0.0173389 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0173268 |
| NRN1 | neuritin 1 | -0.0172285 |
