| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.083712 |
| EZR | ezrin | 0.0530741 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0452022 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0430964 |
| YEATS2 | YEATS domain containing 2 | 0.0419952 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0410284 |
| CAPRIN2 | caprin family member 2 | 0.0405462 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0391224 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0370904 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0355026 |
| RPL3 | ribosomal protein L3 | 0.0340422 |
| FLNB | filamin B, beta | 0.0333707 |
| PRELID2 | PRELI domain containing 2 | 0.0330635 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0324268 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0315435 |
| MT2A | metallothionein 2A | 0.0312655 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0278697 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0276045 |
| LOXL2 | lysyl oxidase-like 2 | 0.0272507 |
| PLEC | plectin | 0.0271986 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0271185 |
| CABIN1 | calcineurin binding protein 1 | 0.0266054 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0265873 |
| NDRG1 | N-myc downstream regulated 1 | 0.0265307 |
| PFKP | phosphofructokinase, platelet | 0.0261474 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0259963 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0251969 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0246967 |
| CDK19 | cyclin-dependent kinase 19 | 0.0246524 |
| BEGAIN | brain-enriched guanylate kinase-associated | 0.0245438 |
| DENND1A | DENN/MADD domain containing 1A | 0.0238163 |
| FMNL2 | formin-like 2 | 0.0237481 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0222694 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0221825 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0219685 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0218446 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0217063 |
| CEP192 | centrosomal protein 192kDa | 0.0215968 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0215888 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0215594 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0214782 |
| PYGB | phosphorylase, glycogen; brain | 0.0214134 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0211468 |
| MCL1 | myeloid cell leukemia 1 | 0.0208821 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0207103 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0206862 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0206212 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0202896 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0201227 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0195621 |
| NBAS | neuroblastoma amplified sequence | 0.0195567 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0193892 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0193723 |
| EPHA2 | EPH receptor A2 | 0.0191986 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0191188 |
| POM121 | POM121 transmembrane nucleoporin | 0.0191095 |
| NAV2 | neuron navigator 2 | 0.0189272 |
| KLC1 | kinesin light chain 1 | 0.0189029 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.018785 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0186068 |
| CEP250 | centrosomal protein 250kDa | 0.0185261 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.01841 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0183209 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | 0.0181993 |
| FAM219A | family with sequence similarity 219, member A | 0.0181935 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0178649 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0178141 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.0177357 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0176684 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.017546 |
| MOK | MOK protein kinase | 0.0175098 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0169787 |
| XPO6 | exportin 6 | 0.0168007 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0167645 |
| KIAA1958 | KIAA1958 | 0.0166304 |
| SFPQ | splicing factor proline/glutamine-rich | 0.016577 |
| FNIP1 | folliculin interacting protein 1 | 0.0165241 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0163572 |
| SLK | STE20-like kinase | 0.0162411 |
| AK2 | adenylate kinase 2 | 0.0162277 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0162149 |
| MINK1 | misshapen-like kinase 1 | 0.0158167 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.015632 |
| RTTN | rotatin | 0.0156018 |
| FLNA | filamin A, alpha | 0.0155839 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0152234 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0150369 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0149104 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0148733 |
| PDE8A | phosphodiesterase 8A | 0.0146513 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0146076 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0145742 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0143408 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0142877 |
| MNMIP1 | manchette microtubule inner protein 1 | 0.0142604 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0140733 |
| PCBP2 | poly(rC) binding protein 2 | 0.0138366 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.013812 |
| POM121C | POM121 transmembrane nucleoporin C | 0.0137337 |
| MYO18A | myosin XVIIIA | 0.0135991 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.164203 |
| VIM | vimentin | -0.15622 |
| TP63 | tumor protein p63 | -0.0974541 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0875091 |
| CD44 | CD44 molecule (Indian blood group) | -0.0872398 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0841397 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0573835 |
| TMSB4X | thymosin beta 4, X-linked | -0.0523157 |
| CANX | calnexin | -0.0511873 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0497774 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0443339 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0430292 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0411617 |
| SP100 | SP100 nuclear antigen | -0.041048 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0399322 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0398597 |
| RIGI | RNA sensor RIG-I | -0.0387891 |
| PTMA | prothymosin, alpha | -0.0373621 |
| EHBP1 | EH domain binding protein 1 | -0.0368809 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0345982 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0345963 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0339454 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0331212 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0310122 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0310099 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0301178 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0292895 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0292079 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0286831 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0286445 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0280206 |
| PLSCR1 | phospholipid scramblase 1 | -0.0279836 |
| TXNRD1 | thioredoxin reductase 1 | -0.0267351 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.02601 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.024908 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0246113 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0245906 |
| FBXO11 | F-box protein 11 | -0.024185 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0235554 |
| RPLP0 | ribosomal protein, large, P0 | -0.0233321 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0232984 |
| POTEF | POTE ankyrin domain family, member F | -0.0230349 |
| KLF6 | Kruppel-like factor 6 | -0.0230204 |
| APP | amyloid beta (A4) precursor protein | -0.023004 |
| LDHA | lactate dehydrogenase A | -0.022717 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0226364 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0225733 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0225531 |
| ANXA2 | annexin A2 | -0.0224875 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0223594 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0223331 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.0221653 |
| TMSB10 | thymosin beta 10 | -0.021983 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0218346 |
| TMEM123 | transmembrane protein 123 | -0.0214238 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0211893 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0210685 |
| RGS4 | regulator of G-protein signaling 4 | -0.0209689 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0209607 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0207434 |
| RPS6 | ribosomal protein S6 | -0.0201893 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.020152 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0200759 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0199719 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0195461 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0195255 |
| TOP1 | topoisomerase (DNA) I | -0.019224 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0191936 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0190017 |
| AHNAK | AHNAK nucleoprotein | -0.0189532 |
| RUNX1 | runt-related transcription factor 1 | -0.0188579 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0188484 |
| HMGA1 | high mobility group AT-hook 1 | -0.0186832 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0185741 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0184682 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0184665 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0184011 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0184004 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0183676 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0183486 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0182683 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0182382 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0179558 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0179303 |
| JMJD1C | jumonji domain containing 1C | -0.0177463 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0174657 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0174581 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0173416 |
| RPL12 | ribosomal protein L12 | -0.0172694 |
| IPO7 | importin 7 | -0.0171812 |
| PMP22 | peripheral myelin protein 22 | -0.0169267 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.016623 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0166088 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0165583 |
| OSMR | oncostatin M receptor | -0.0164541 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0164018 |
| ERBIN | erbb2 interacting protein | -0.0162901 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0162831 |
| BPTF | bromodomain PHD finger transcription factor | -0.0162206 |
| WDR43 | WD repeat domain 43 | -0.0161769 |
