| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fluvoxamine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.139808 |
| MT2A | metallothionein 2A | 0.111335 |
| NAV2 | neuron navigator 2 | 0.110696 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.10674 |
| SMAD3 | SMAD family member 3 | 0.101593 |
| NDRG1 | N-myc downstream regulated 1 | 0.101591 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.10118 |
| PCBP2 | poly(rC) binding protein 2 | 0.0821187 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0784674 |
| TGM2 | transglutaminase 2 | 0.0590633 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.058827 |
| FLNB | filamin B, beta | 0.0550432 |
| VEGFA | vascular endothelial growth factor A | 0.0489708 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0455019 |
| PFKP | phosphofructokinase, platelet | 0.0430492 |
| FAM13A | family with sequence similarity 13, member A | 0.0415089 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0395467 |
| RPL3 | ribosomal protein L3 | 0.0395069 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0384993 |
| CA12 | carbonic anhydrase XII | 0.037061 |
| RUNX1 | runt-related transcription factor 1 | 0.0366822 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0360469 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0345876 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0342293 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0340049 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0326175 |
| CABIN1 | calcineurin binding protein 1 | 0.0319194 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0314148 |
| NGLY1 | N-glycanase 1 | 0.0313845 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.030967 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0308857 |
| EGFR | epidermal growth factor receptor | 0.0308784 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0298523 |
| ANGPTL4 | angiopoietin-like 4 | 0.0297268 |
| HELZ | helicase with zinc finger | 0.029544 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0288035 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0286735 |
| FAM219A | family with sequence similarity 219, member A | 0.0273836 |
| EFNA5 | ephrin-A5 | 0.0273009 |
| MTSS1 | metastasis suppressor 1 | 0.0259455 |
| FTL | ferritin, light polypeptide | 0.0259056 |
| LOXL2 | lysyl oxidase-like 2 | 0.0258272 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0257835 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0253375 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0246143 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0241245 |
| SEPTIN9 | septin 9 | 0.0239851 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0239253 |
| YEATS2 | YEATS domain containing 2 | 0.0238837 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0238735 |
| RPS19 | ribosomal protein S19 | 0.0237128 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0234181 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0232276 |
| ARRDC3 | arrestin domain containing 3 | 0.0230978 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0230733 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0230302 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0230108 |
| CEP250 | centrosomal protein 250kDa | 0.0226234 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.022403 |
| ATP13A3 | ATPase type 13A3 | 0.0221604 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0219672 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0214167 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0213789 |
| MLPH | melanophilin | 0.0211544 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0208031 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0207804 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0205806 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0205459 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0204859 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0204051 |
| FAM20C | family with sequence similarity 20, member C | 0.0203818 |
| NOTCH2 | notch 2 | 0.020027 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0199405 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0196822 |
| CCNL1 | cyclin L1 | 0.0196262 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0196177 |
| ZNF638 | zinc finger protein 638 | 0.0195812 |
| MYO1B | myosin IB | 0.0191656 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0191618 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0191405 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0190689 |
| SETD5 | SET domain containing 5 | 0.0190454 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 0.0190444 |
| PKM | pyruvate kinase, muscle | 0.0190048 |
| RARB | retinoic acid receptor, beta | 0.0189057 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0185938 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0183461 |
| FOSL1 | FOS-like antigen 1 | 0.0183287 |
| ANO6 | anoctamin 6 | 0.018125 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0179921 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0179683 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0179129 |
| ADM | adrenomedullin | 0.017875 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0178186 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0178137 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0175306 |
| CCNY | cyclin Y | 0.0172962 |
| ECE1 | endothelin converting enzyme 1 | 0.0172628 |
| FAM120A | family with sequence similarity 120A | 0.017201 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0171331 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.153597 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.146655 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.109364 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0942009 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.094166 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0864596 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0772171 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0726267 |
| CANX | calnexin | -0.0640149 |
| CD44 | CD44 molecule (Indian blood group) | -0.0586373 |
| NRG1 | neuregulin 1 | -0.0583027 |
| HMGA2 | high mobility group AT-hook 2 | -0.0566299 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.055733 |
| LOX | lysyl oxidase | -0.054476 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0540883 |
| GLCCI1 | glucocorticoid induced 1 | -0.0539012 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0526362 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.052271 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0509854 |
| RBM39 | RNA binding motif protein 39 | -0.0499421 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0442237 |
| IER3 | immediate early response 3 | -0.0438556 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0438002 |
| ZNF804A | zinc finger protein 804A | -0.0435819 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.042727 |
| DST | dystonin | -0.0423923 |
| OSMR | oncostatin M receptor | -0.0419415 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0406813 |
| RAI14 | retinoic acid induced 14 | -0.0398127 |
| TMEM263 | transmembrane protein 263 | -0.0395989 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0394945 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0393357 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0391232 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0388482 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0387689 |
| MAP1B | microtubule-associated protein 1B | -0.0382691 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0377455 |
| EHBP1 | EH domain binding protein 1 | -0.0374402 |
| VCL | vinculin | -0.0368534 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0364881 |
| SYT1 | synaptotagmin I | -0.0350867 |
| GPC6 | glypican 6 | -0.0343007 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0336553 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0330457 |
| NTN4 | netrin 4 | -0.0328304 |
| CALU | calumenin | -0.0326774 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0324836 |
| PTMA | prothymosin, alpha | -0.0319757 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0317312 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0313774 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0313539 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0310875 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0310273 |
| NRP1 | neuropilin 1 | -0.0307471 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0301253 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0300699 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0299973 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.029904 |
| SYAP1 | synapse associated protein 1 | -0.0296291 |
| TMSB10 | thymosin beta 10 | -0.0293683 |
| VRK2 | vaccinia related kinase 2 | -0.0293563 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0290094 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0288487 |
| TMSB4X | thymosin beta 4, X-linked | -0.028274 |
| CDK13 | cyclin-dependent kinase 13 | -0.0281751 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0281412 |
| FN1 | fibronectin 1 | -0.0279851 |
| MORF4L2 | mortality factor 4 like 2 | -0.0278977 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0277327 |
| PARD3 | par-3 family cell polarity regulator | -0.0277191 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0276566 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0271614 |
| ATM | ATM serine/threonine kinase | -0.0267242 |
| ARF1 | ADP-ribosylation factor 1 | -0.026446 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0264426 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.026327 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0263101 |
| KYNU | kynureninase | -0.026282 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0258478 |
| GLIS3 | GLIS family zinc finger 3 | -0.025278 |
| GNAS | GNAS complex locus | -0.025218 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0250794 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0248227 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.024735 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0247182 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0246463 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0245062 |
| TXNRD1 | thioredoxin reductase 1 | -0.024321 |
| EXOC6B | exocyst complex component 6B | -0.0242636 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0242625 |
| AHNAK | AHNAK nucleoprotein | -0.0237845 |
| ANXA2 | annexin A2 | -0.0236781 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0236468 |
| ETV6 | ets variant 6 | -0.0236336 |
| JMJD1C | jumonji domain containing 1C | -0.0236256 |
| NAV3 | neuron navigator 3 | -0.0235512 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0234915 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.023387 |
| YME1L1 | YME1-like 1 ATPase | -0.0232251 |
| SEC24A | SEC24 family member A | -0.0230893 |
