| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.123242 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0898237 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0891428 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.086302 |
| FMNL2 | formin-like 2 | 0.0857056 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0844335 |
| MCL1 | myeloid cell leukemia 1 | 0.0787741 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0780527 |
| FLNB | filamin B, beta | 0.076506 |
| CMIP | c-Maf inducing protein | 0.0753995 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0748681 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0729653 |
| RPL3 | ribosomal protein L3 | 0.0673318 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0670511 |
| PYGL | phosphorylase, glycogen, liver | 0.0619955 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0616539 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0574059 |
| FLNA | filamin A, alpha | 0.0559036 |
| PDE8A | phosphodiesterase 8A | 0.0549554 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0504862 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0489894 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0482033 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.047974 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0468816 |
| ITGB5 | integrin, beta 5 | 0.042701 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0423844 |
| TPD52 | tumor protein D52 | 0.0419634 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0404152 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0399849 |
| NDRG1 | N-myc downstream regulated 1 | 0.0388126 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0387775 |
| APP | amyloid beta (A4) precursor protein | 0.0382357 |
| SMAD3 | SMAD family member 3 | 0.0374051 |
| CABIN1 | calcineurin binding protein 1 | 0.0365235 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0364841 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0363214 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0362952 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.036135 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0360358 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0348829 |
| PLEC | plectin | 0.0348708 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0345006 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0339986 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0339598 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0336296 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0334511 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0333225 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0330693 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0329913 |
| PRKCE | protein kinase C, epsilon | 0.0329548 |
| ACTN1 | actinin, alpha 1 | 0.032728 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.0325569 |
| FNBP1L | formin binding protein 1-like | 0.0323115 |
| USP36 | ubiquitin specific peptidase 36 | 0.0322843 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0315549 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.031009 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0307978 |
| TPM3 | tropomyosin 3 | 0.0307962 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0303307 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0303106 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0298269 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0297793 |
| COPA | coatomer protein complex, subunit alpha | 0.029687 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0292994 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0290978 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0290664 |
| FTO | fat mass and obesity associated | 0.0289627 |
| LAMA5 | laminin, alpha 5 | 0.0289247 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0284671 |
| CALR | calreticulin | 0.0284192 |
| CCNY | cyclin Y | 0.028047 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0279512 |
| RNF145 | ring finger protein 145 | 0.0275996 |
| BRD2 | bromodomain containing 2 | 0.0273933 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0268406 |
| MEF2D | myocyte enhancer factor 2D | 0.025741 |
| NUP153 | nucleoporin 153kDa | 0.0255628 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0253128 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0252664 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0252662 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0251112 |
| CTBP2 | C-terminal binding protein 2 | 0.0247644 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.0245152 |
| NUP58 | nucleoporin 58 | 0.0244885 |
| PKM | pyruvate kinase, muscle | 0.0239506 |
| PFKP | phosphofructokinase, platelet | 0.0238947 |
| USP3 | ubiquitin specific peptidase 3 | 0.0238554 |
| GRAMD1B | GRAM domain containing 1B | 0.0236619 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0236555 |
| DNMBP | dynamin binding protein | 0.0234332 |
| PCBP2 | poly(rC) binding protein 2 | 0.0233153 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0233014 |
| RBM6 | RNA binding motif protein 6 | 0.0232259 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0228544 |
| CTNNBL1 | catenin, beta like 1 | 0.0227946 |
| MOK | MOK protein kinase | 0.0227448 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0226813 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0221859 |
| SLMAP | sarcolemma associated protein | 0.0221516 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0220858 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.206791 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.16574 |
| TXNRD1 | thioredoxin reductase 1 | -0.153585 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.136665 |
| VIM | vimentin | -0.113342 |
| FTL | ferritin, light polypeptide | -0.0890192 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0886131 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0854677 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0793748 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0751406 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0721489 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0680273 |
| PTMA | prothymosin, alpha | -0.0674481 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0643945 |
| TMSB10 | thymosin beta 10 | -0.0630747 |
| BICC1 | BicC family RNA binding protein 1 | -0.0564023 |
| WWOX | WW domain containing oxidoreductase | -0.0560341 |
| RPS21 | ribosomal protein S21 | -0.0507671 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0474992 |
| ASPH | aspartate beta-hydroxylase | -0.047123 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0456138 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0443347 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0436066 |
| RPS27A | ribosomal protein S27a | -0.0420735 |
| RPLP1 | ribosomal protein, large, P1 | -0.0409059 |
| RPLP0 | ribosomal protein, large, P0 | -0.0404151 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0390853 |
| CENPF | centromere protein F, 350/400kDa | -0.0373751 |
| IER3 | immediate early response 3 | -0.0372545 |
| FGB | fibrinogen beta chain | -0.0372338 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0370447 |
| ANXA2 | annexin A2 | -0.037034 |
| HDAC9 | histone deacetylase 9 | -0.0366297 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0364281 |
| RPS24 | ribosomal protein S24 | -0.0359502 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0357575 |
| NEGR1 | neuronal growth regulator 1 | -0.0352622 |
| OSMR | oncostatin M receptor | -0.035006 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0349554 |
| NNMT | nicotinamide N-methyltransferase | -0.0342567 |
| S100A6 | S100 calcium binding protein A6 | -0.0316836 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0314196 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0314039 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0313689 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0312035 |
| RPL26 | ribosomal protein L26 | -0.0309383 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0296719 |
| MAP1B | microtubule-associated protein 1B | -0.0291208 |
| RPS5 | ribosomal protein S5 | -0.0289194 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0288812 |
| NRG1 | neuregulin 1 | -0.0286814 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0280058 |
| MTDH | metadherin | -0.0277806 |
| MORF4L2 | mortality factor 4 like 2 | -0.0275827 |
| SQSTM1 | sequestosome 1 | -0.0263772 |
| EHBP1 | EH domain binding protein 1 | -0.0263288 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0259535 |
| RPL35A | ribosomal protein L35a | -0.0254298 |
| ZNF804A | zinc finger protein 804A | -0.0247896 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.024657 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0240646 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0239649 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0239033 |
| NTN4 | netrin 4 | -0.0236641 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0235397 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0232323 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0231724 |
| CANX | calnexin | -0.0231373 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0230947 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0230789 |
| RPS25 | ribosomal protein S25 | -0.0230551 |
| NAV3 | neuron navigator 3 | -0.022939 |
| CENPE | centromere protein E, 312kDa | -0.0228964 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0228934 |
| RPL38 | ribosomal protein L38 | -0.0225998 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0225872 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.02236 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0222661 |
| RSPO3 | R-spondin 3 | -0.0222585 |
| ATM | ATM serine/threonine kinase | -0.0221687 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0221035 |
| RPS20 | ribosomal protein S20 | -0.021941 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0217328 |
| RPL23 | ribosomal protein L23 | -0.0216887 |
| RFWD3 | ring finger and WD repeat domain 3 | -0.0215468 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0213748 |
| FHIT | fragile histidine triad | -0.0211326 |
| EPGN | epithelial mitogen | -0.0206665 |
| BPTF | bromodomain PHD finger transcription factor | -0.0206632 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0206569 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0206229 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0205915 |
| VCL | vinculin | -0.0203048 |
| RPL7 | ribosomal protein L7 | -0.0201288 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0200685 |
| CEP128 | centrosomal protein 128kDa | -0.0200505 |
| RPS16 | ribosomal protein S16 | -0.0199729 |
| GNAS | GNAS complex locus | -0.0198018 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0195726 |
| SRGN | serglycin | -0.01954 |
