| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fluvoxamine_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.17844 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.142729 |
| RNF145 | ring finger protein 145 | 0.142544 |
| DSCAM | Down syndrome cell adhesion molecule | 0.132996 |
| NDRG1 | N-myc downstream regulated 1 | 0.116464 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.110771 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.104857 |
| LAMB3 | laminin, beta 3 | 0.103892 |
| JMJD1C | jumonji domain containing 1C | 0.0991906 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0865506 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.084148 |
| ZNF292 | zinc finger protein 292 | 0.0836096 |
| FNIP1 | folliculin interacting protein 1 | 0.0802321 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0799155 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0786259 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.077623 |
| RUNX1 | runt-related transcription factor 1 | 0.0755173 |
| CCNY | cyclin Y | 0.0676608 |
| COG5 | component of oligomeric golgi complex 5 | 0.0676338 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0670403 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0659084 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0638247 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0624193 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0621179 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0614798 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0613511 |
| RAB7A | RAB7A, member RAS oncogene family | 0.060139 |
| PRKCA | protein kinase C, alpha | 0.0582837 |
| CA12 | carbonic anhydrase XII | 0.0578312 |
| NUP58 | nucleoporin 58 | 0.057252 |
| NBAS | neuroblastoma amplified sequence | 0.0554747 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.055284 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0544499 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0540642 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0536017 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0521951 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0509042 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0501993 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0499802 |
| VMP1 | vacuole membrane protein 1 | 0.0497952 |
| KLF6 | Kruppel-like factor 6 | 0.0497932 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0489793 |
| EFNA5 | ephrin-A5 | 0.0488793 |
| SBF2 | SET binding factor 2 | 0.0470139 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0459042 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.044533 |
| LAMC2 | laminin, gamma 2 | 0.0442196 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0432598 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0430415 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0410515 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0408137 |
| CERT1 | ceramide transporter 1 | 0.0406694 |
| PCM1 | pericentriolar material 1 | 0.0398829 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0386466 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0367434 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0356412 |
| SDC4 | syndecan 4 | 0.0355039 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.035266 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.033813 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0336706 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0333215 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0329212 |
| SMAD3 | SMAD family member 3 | 0.0324667 |
| ZNF207 | zinc finger protein 207 | 0.0323749 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0312781 |
| CTBP2 | C-terminal binding protein 2 | 0.0312735 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0296981 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0291753 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0286377 |
| ACTN4 | actinin, alpha 4 | 0.0280789 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0270626 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0268959 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0268872 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0263587 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0260698 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0260019 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0254923 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0246961 |
| ASPH | aspartate beta-hydroxylase | 0.0246127 |
| ANXA1 | annexin A1 | 0.0238125 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0236921 |
| EGFR | epidermal growth factor receptor | 0.0216531 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0215333 |
| FMNL2 | formin-like 2 | 0.0209056 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.020796 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0206997 |
| PDE10A | phosphodiesterase 10A | 0.020156 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.019979 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0192614 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0187857 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0181689 |
| USP34 | ubiquitin specific peptidase 34 | 0.0180706 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0180021 |
| PTK2 | protein tyrosine kinase 2 | 0.0177674 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0172422 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0172242 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0168894 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0168329 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0167212 |
| RORA | RAR-related orphan receptor A | 0.0165703 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.206924 |
| VIM | vimentin | -0.140814 |
| FTL | ferritin, light polypeptide | -0.129948 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.109514 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.107142 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0841565 |
| MYO1E | myosin IE | -0.083906 |
| ANXA2 | annexin A2 | -0.0837987 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0811133 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0792284 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0788179 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0771506 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0743986 |
| TMSB10 | thymosin beta 10 | -0.0739946 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0729667 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0696796 |
| RPL23 | ribosomal protein L23 | -0.0679866 |
| RPS19 | ribosomal protein S19 | -0.0645795 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0643298 |
| LMO7 | LIM domain 7 | -0.0642536 |
| PTMA | prothymosin, alpha | -0.0622883 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.061087 |
| RIGI | RNA sensor RIG-I | -0.0608659 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0592345 |
| NEBL | nebulette | -0.0591431 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0584204 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0582602 |
| PARD3 | par-3 family cell polarity regulator | -0.0579481 |
| ENO1 | enolase 1, (alpha) | -0.0556813 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0544682 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0526697 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0526121 |
| PHF21A | PHD finger protein 21A | -0.0524361 |
| PGK1 | phosphoglycerate kinase 1 | -0.0523365 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0511003 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0509597 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0494239 |
| POTEF | POTE ankyrin domain family, member F | -0.0489547 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0481471 |
| GOLGB1 | golgin B1 | -0.047474 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0465007 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0462196 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0459955 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0459858 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0456242 |
| AHNAK | AHNAK nucleoprotein | -0.0445348 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.043695 |
| SMYD3 | SET and MYND domain containing 3 | -0.0424176 |
| ATOSA | atos homolog A | -0.0420406 |
| RPL19 | ribosomal protein L19 | -0.0418066 |
| SQSTM1 | sequestosome 1 | -0.0408465 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0408155 |
| CANX | calnexin | -0.0403659 |
| KIAA1217 | KIAA1217 | -0.0393707 |
| MYOF | myoferlin | -0.0390351 |
| HLA-B | major histocompatibility complex, class I, B | -0.0385801 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0383477 |
| B2M | beta-2-microglobulin | -0.0379918 |
| CD44 | CD44 molecule (Indian blood group) | -0.0355065 |
| PRELID2 | PRELI domain containing 2 | -0.0351736 |
| MYO5B | myosin VB | -0.035082 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0348572 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0338687 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0334664 |
| GPC6 | glypican 6 | -0.0323487 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0321432 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0313785 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0310815 |
| RTN4 | reticulon 4 | -0.0308211 |
| TJP1 | tight junction protein 1 | -0.030535 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.030357 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0302884 |
| FN1 | fibronectin 1 | -0.0299613 |
| ERBIN | erbb2 interacting protein | -0.0299174 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0295693 |
| ACTG1 | actin gamma 1 | -0.0270666 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0265064 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0259668 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0254345 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0240517 |
| USP53 | ubiquitin specific peptidase 53 | -0.0231513 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0223392 |
| ZNF638 | zinc finger protein 638 | -0.0221936 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.022188 |
| SPAG9 | sperm associated antigen 9 | -0.0213531 |
| SVIL | supervillin | -0.0213028 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.021088 |
| OSMR | oncostatin M receptor | -0.0197529 |
| MUC16 | mucin 16, cell surface associated | -0.0196787 |
| TOP1 | topoisomerase (DNA) I | -0.0196149 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0193872 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0192703 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0183246 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0174704 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0170872 |
| KRT17 | keratin 17, type I | -0.0170024 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0161992 |
| RPS6 | ribosomal protein S6 | -0.0159683 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.015968 |
| SRPK2 | SRSF protein kinase 2 | -0.0153045 |
