| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fluvoxamine_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.08961 |
| TXNRD1 | thioredoxin reductase 1 | 0.0645391 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0542321 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0496423 |
| PCBP2 | poly(rC) binding protein 2 | 0.0429658 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0424134 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0411947 |
| RTN4 | reticulon 4 | 0.0392396 |
| RPL3 | ribosomal protein L3 | 0.0382209 |
| ZNF638 | zinc finger protein 638 | 0.0377745 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0374271 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0369746 |
| ATP11A | ATPase, class VI, type 11A | 0.034989 |
| MSN | moesin | 0.0338576 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0336046 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0333582 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0319381 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0318808 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0314278 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0311593 |
| RAD51B | RAD51 paralog B | 0.0303817 |
| GRAMD1B | GRAM domain containing 1B | 0.0299276 |
| SMAD3 | SMAD family member 3 | 0.0287422 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0283092 |
| RNF145 | ring finger protein 145 | 0.0282863 |
| FLNA | filamin A, alpha | 0.0280672 |
| ETNK1 | ethanolamine kinase 1 | 0.0279226 |
| CCNL1 | cyclin L1 | 0.0278618 |
| PLEC | plectin | 0.0277737 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0262897 |
| PTEN | phosphatase and tensin homolog | 0.0262558 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0259712 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0256349 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0255225 |
| COPA | coatomer protein complex, subunit alpha | 0.0254369 |
| XPO1 | exportin 1 | 0.0245784 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0245663 |
| CEP192 | centrosomal protein 192kDa | 0.0245341 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0244472 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0243243 |
| TMEM165 | transmembrane protein 165 | 0.0242438 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0241064 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0239358 |
| RNF38 | ring finger protein 38 | 0.0234663 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0232674 |
| NCKAP1 | NCK-associated protein 1 | 0.0231384 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0229931 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0228854 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0228507 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0225159 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0219563 |
| COG5 | component of oligomeric golgi complex 5 | 0.0218729 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0218237 |
| PNN | pinin, desmosome associated protein | 0.0214219 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0212622 |
| MED13L | mediator complex subunit 13-like | 0.021073 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0210143 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0209529 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0209086 |
| YAP1 | Yes-associated protein 1 | 0.0208269 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0204544 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0202589 |
| ZNF292 | zinc finger protein 292 | 0.0201062 |
| NOTCH2 | notch 2 | 0.0200064 |
| WDR43 | WD repeat domain 43 | 0.0199545 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0199199 |
| PFKP | phosphofructokinase, platelet | 0.0198855 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0198408 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0197921 |
| SP3 | Sp3 transcription factor | 0.0197137 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.019503 |
| FOXJ3 | forkhead box J3 | 0.0194926 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.0194358 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0193322 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0192676 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0190891 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | 0.0189431 |
| RRM2 | ribonucleotide reductase M2 | 0.0188853 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0188398 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0187783 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0187495 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0187434 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0185248 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0184596 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0183985 |
| DIDO1 | death inducer-obliterator 1 | 0.0183357 |
| CDYL | chromodomain protein, Y-like | 0.0182572 |
| NUP153 | nucleoporin 153kDa | 0.0181442 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0179342 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0178406 |
| EXOC6B | exocyst complex component 6B | 0.0177729 |
| USP24 | ubiquitin specific peptidase 24 | 0.0177648 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0175563 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0174444 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0174374 |
| BRD4 | bromodomain containing 4 | 0.0173698 |
| NUP155 | nucleoporin 155kDa | 0.0173339 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0170594 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.0170386 |
| PTK2 | protein tyrosine kinase 2 | 0.0169839 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.263615 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.261056 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.100481 |
| VIM | vimentin | -0.0832436 |
| YBX3 | Y box binding protein 3 | -0.0826592 |
| PTMA | prothymosin, alpha | -0.0808615 |
| ACTG1 | actin gamma 1 | -0.064995 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0631181 |
| TMSB10 | thymosin beta 10 | -0.0608641 |
| TPI1 | triosephosphate isomerase 1 | -0.0567848 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0551115 |
| OSMR | oncostatin M receptor | -0.0521142 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0493441 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.048921 |
| CAVIN1 | caveolae associated protein 1 | -0.0480576 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0463143 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0456242 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.045595 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0450346 |
| STC1 | stanniocalcin 1 | -0.0432425 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0422153 |
| HLA-B | major histocompatibility complex, class I, B | -0.0414793 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0400533 |
| RPL26 | ribosomal protein L26 | -0.0394084 |
| TPM4 | tropomyosin 4 | -0.0389002 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0381888 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0361993 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0360783 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.035642 |
| RPS3 | ribosomal protein S3 | -0.0354752 |
| RYR3 | ryanodine receptor 3 | -0.0346856 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0331722 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0329251 |
| HMGA2 | high mobility group AT-hook 2 | -0.0323553 |
| RPL12 | ribosomal protein L12 | -0.0316063 |
| IER3 | immediate early response 3 | -0.0308951 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0304909 |
| H1-0 | H1.0 linker histone | -0.0295219 |
| RPS15 | ribosomal protein S15 | -0.0288152 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0284771 |
| RPL11 | ribosomal protein L11 | -0.0277933 |
| MT2A | metallothionein 2A | -0.027528 |
| PDE10A | phosphodiesterase 10A | -0.0273957 |
| S100A10 | S100 calcium binding protein A10 | -0.027205 |
| CCND1 | cyclin D1 | -0.0271995 |
| RPL37 | ribosomal protein L37 | -0.0270154 |
| KRT18 | keratin 18, type I | -0.0266169 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0265523 |
| RPL37A | ribosomal protein L37a | -0.0262598 |
| VCL | vinculin | -0.0261511 |
| RPS8 | ribosomal protein S8 | -0.026134 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0255906 |
| GNAS | GNAS complex locus | -0.0255393 |
| RPL8 | ribosomal protein L8 | -0.0254026 |
| CUX1 | cut-like homeobox 1 | -0.0253705 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0248447 |
| RPS27 | ribosomal protein S27 | -0.0248253 |
| RPS29 | ribosomal protein S29 | -0.024649 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0243348 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0239642 |
| AHNAK | AHNAK nucleoprotein | -0.0237886 |
| RPLP1 | ribosomal protein, large, P1 | -0.0233846 |
| RPS19 | ribosomal protein S19 | -0.0232955 |
| SSH2 | slingshot protein phosphatase 2 | -0.0231926 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0228575 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0228403 |
| ENO1 | enolase 1, (alpha) | -0.0228122 |
| RPL32 | ribosomal protein L32 | -0.0226962 |
| RPL19 | ribosomal protein L19 | -0.0226686 |
| CANX | calnexin | -0.0226092 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0224693 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0220396 |
| RPS21 | ribosomal protein S21 | -0.0216387 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0215791 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0214235 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0211386 |
| RPLP2 | ribosomal protein, large, P2 | -0.0205594 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0203797 |
| RPL36 | ribosomal protein L36 | -0.0203472 |
| KLF6 | Kruppel-like factor 6 | -0.0202807 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0199548 |
| RPL35 | ribosomal protein L35 | -0.0197097 |
| CALR | calreticulin | -0.0196737 |
| BPTF | bromodomain PHD finger transcription factor | -0.0192894 |
| NLGN1 | neuroligin 1 | -0.0192054 |
| TRIM9 | tripartite motif containing 9 | -0.019195 |
| PYGL | phosphorylase, glycogen, liver | -0.0191346 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0191205 |
| RPL34 | ribosomal protein L34 | -0.0190089 |
| RPS27A | ribosomal protein S27a | -0.0189831 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0188842 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0188686 |
| FTL | ferritin, light polypeptide | -0.0188578 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0188102 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0186841 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0184957 |
| ZNF217 | zinc finger protein 217 | -0.0183042 |
| DEK | DEK proto-oncogene | -0.0180478 |
| RPL35A | ribosomal protein L35a | -0.0179964 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0179664 |
