| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.303451 |
| FN1 | fibronectin 1 | 0.225114 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.143538 |
| FNDC3B | fibronectin type III domain containing 3B | 0.139081 |
| TSC22D2 | TSC22 domain family, member 2 | 0.104882 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0989655 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0979236 |
| PLEC | plectin | 0.095633 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0906871 |
| PGK1 | phosphoglycerate kinase 1 | 0.086913 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0858167 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0839688 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0797812 |
| PTK2 | protein tyrosine kinase 2 | 0.0723303 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0718837 |
| LAMB3 | laminin, beta 3 | 0.0705051 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0700219 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0631897 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.06281 |
| RNF145 | ring finger protein 145 | 0.0627272 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0589766 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0564931 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0557804 |
| TOP1 | topoisomerase (DNA) I | 0.0554787 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0551461 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0550481 |
| ARRDC3 | arrestin domain containing 3 | 0.0548364 |
| FAM13A | family with sequence similarity 13, member A | 0.0547184 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0546243 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0540984 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.053367 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0524166 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0516309 |
| TFG | TRK-fused gene | 0.0514632 |
| ZNF292 | zinc finger protein 292 | 0.0514094 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0508254 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0504568 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0502519 |
| RHEB | Ras homolog enriched in brain | 0.0491119 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.04822 |
| RPL3 | ribosomal protein L3 | 0.047968 |
| CALR | calreticulin | 0.0473956 |
| RBM39 | RNA binding motif protein 39 | 0.0473424 |
| USP3 | ubiquitin specific peptidase 3 | 0.0466842 |
| MATR3 | matrin 3 | 0.0464163 |
| LDHA | lactate dehydrogenase A | 0.0455826 |
| ACTG1 | actin gamma 1 | 0.0453872 |
| RACK1 | receptor for activated C kinase 1 | 0.0445419 |
| SLMAP | sarcolemma associated protein | 0.0443897 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0440463 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.043847 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0437991 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.043647 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0428827 |
| CDC73 | cell division cycle 73 | 0.0426401 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0426322 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0426211 |
| UPP1 | uridine phosphorylase 1 | 0.0421303 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0415039 |
| CCNL1 | cyclin L1 | 0.0414621 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0410216 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0408177 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0403868 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0403524 |
| VEGFA | vascular endothelial growth factor A | 0.0399901 |
| NCKAP1 | NCK-associated protein 1 | 0.0399076 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0397404 |
| TXNRD1 | thioredoxin reductase 1 | 0.0397268 |
| PKM | pyruvate kinase, muscle | 0.0396594 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0395511 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0395219 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0388873 |
| FLNA | filamin A, alpha | 0.0386008 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0385253 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0383266 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0381053 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.037734 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0373615 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0372884 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0371331 |
| RPL4 | ribosomal protein L4 | 0.0365374 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0361407 |
| NUP58 | nucleoporin 58 | 0.0358222 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0357594 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0354584 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0351893 |
| DUSP10 | dual specificity phosphatase 10 | 0.0349949 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0348434 |
| MXD1 | MAX dimerization protein 1 | 0.0342426 |
| IRF6 | interferon regulatory factor 6 | 0.0339399 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0338798 |
| MEF2A | myocyte enhancer factor 2A | 0.0336551 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0335229 |
| YTHDC1 | YTH domain containing 1 | 0.0332189 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0331519 |
| NPTN | neuroplastin | 0.0330489 |
| FLNB | filamin B, beta | 0.0324769 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0323412 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0323407 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0323367 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.132837 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.092511 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0844639 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0678696 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0674606 |
| FTL | ferritin, light polypeptide | -0.0607319 |
| EFNA5 | ephrin-A5 | -0.0575727 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0562601 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0539397 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0513763 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0468122 |
| TMSB10 | thymosin beta 10 | -0.0460774 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0455545 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.042304 |
| FBXO32 | F-box protein 32 | -0.0413135 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0407711 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0403561 |
| MT2A | metallothionein 2A | -0.0402347 |
| RIGI | RNA sensor RIG-I | -0.0377342 |
| VCL | vinculin | -0.0376541 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0376329 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0372782 |
| GOLGB1 | golgin B1 | -0.034294 |
| S100A6 | S100 calcium binding protein A6 | -0.0342338 |
| MAP1B | microtubule-associated protein 1B | -0.0314942 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0311852 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0303282 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0295735 |
| MYO1E | myosin IE | -0.0291244 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0284515 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0279585 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0278099 |
| PLSCR1 | phospholipid scramblase 1 | -0.0275573 |
| ETV6 | ets variant 6 | -0.0274892 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0273443 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0257853 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0252966 |
| RASAL2 | RAS protein activator like 2 | -0.025221 |
| FNIP1 | folliculin interacting protein 1 | -0.0251111 |
| MX2 | MX dynamin-like GTPase 2 | -0.0249914 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0247248 |
| RPLP1 | ribosomal protein, large, P1 | -0.0240435 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.0232813 |
| EGFR | epidermal growth factor receptor | -0.0231714 |
| RAI14 | retinoic acid induced 14 | -0.0227053 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0225898 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0225299 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0223207 |
| FRMD5 | FERM domain containing 5 | -0.0223003 |
| DSG2 | desmoglein 2 | -0.0222796 |
| VGLL3 | vestigial-like family member 3 | -0.0220955 |
| AHNAK | AHNAK nucleoprotein | -0.0219769 |
| S100A10 | S100 calcium binding protein A10 | -0.0219161 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0218784 |
| SYT1 | synaptotagmin I | -0.0218413 |
| DSPP | dentin sialophosphoprotein | -0.0216321 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0216217 |
| RNF213 | ring finger protein 213 | -0.0215943 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0210346 |
| INTS6 | integrator complex subunit 6 | -0.0207511 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0204723 |
| ATXN1 | ataxin 1 | -0.0202168 |
| CDK13 | cyclin-dependent kinase 13 | -0.0201888 |
| TXNIP | thioredoxin interacting protein | -0.0201082 |
| RAD51B | RAD51 paralog B | -0.0200836 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0199134 |
| RPS19 | ribosomal protein S19 | -0.0198647 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0198566 |
| SP100 | SP100 nuclear antigen | -0.0197079 |
| RBM47 | RNA binding motif protein 47 | -0.0196849 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.019622 |
| RPLP2 | ribosomal protein, large, P2 | -0.0196218 |
| ERBIN | erbb2 interacting protein | -0.0195089 |
| TJP1 | tight junction protein 1 | -0.0192512 |
| SON | SON DNA binding protein | -0.0190696 |
| RRBP1 | ribosome binding protein 1 | -0.0190593 |
| HMGA1 | high mobility group AT-hook 1 | -0.0189974 |
| PALLD | palladin, cytoskeletal associated protein | -0.018947 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0188435 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0187175 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.018656 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0185984 |
| KRT19 | keratin 19, type I | -0.018309 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.018227 |
| CUX1 | cut-like homeobox 1 | -0.0181635 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0181011 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.018048 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.017944 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0178861 |
| HMGA2 | high mobility group AT-hook 2 | -0.0178504 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0177715 |
| NABP1 | nucleic acid binding protein 1 | -0.0177676 |
| RPL28 | ribosomal protein L28 | -0.0176655 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0176515 |
| PMP22 | peripheral myelin protein 22 | -0.0176374 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0176178 |
| TBCA | tubulin folding cofactor A | -0.0175841 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0175463 |
| PGBD5 | piggyBac transposable element derived 5 | -0.0174921 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0174383 |
