| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fluvoxamine_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.102233 |
| PDE10A | phosphodiesterase 10A | 0.0989858 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0968225 |
| EFNA5 | ephrin-A5 | 0.0915213 |
| MCL1 | myeloid cell leukemia 1 | 0.0798191 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0648314 |
| GRAMD1B | GRAM domain containing 1B | 0.0641764 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0625188 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0588209 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0552507 |
| KYNU | kynureninase | 0.0515237 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0486365 |
| FLNB | filamin B, beta | 0.0471653 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0457784 |
| PCBP3 | poly(rC) binding protein 3 | 0.0449165 |
| MYOF | myoferlin | 0.0446274 |
| NRCAM | neuronal cell adhesion molecule | 0.0444604 |
| ASPH | aspartate beta-hydroxylase | 0.0430031 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0423661 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0423113 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0406404 |
| TBXT | T-box transcription factor T | 0.0399688 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0399108 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0395128 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0358089 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0356187 |
| FLNA | filamin A, alpha | 0.0350444 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0347514 |
| RPL3 | ribosomal protein L3 | 0.0344372 |
| NBAS | neuroblastoma amplified sequence | 0.0332171 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0320819 |
| NEK7 | NIMA-related kinase 7 | 0.0312889 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0307651 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0305743 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0301108 |
| CTBP2 | C-terminal binding protein 2 | 0.0295485 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0292655 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0292071 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.029061 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0287491 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0286361 |
| NDRG1 | N-myc downstream regulated 1 | 0.0284939 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0278477 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0272333 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0269803 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0269595 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0267559 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0264124 |
| PRELID2 | PRELI domain containing 2 | 0.0263683 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0262638 |
| HELZ | helicase with zinc finger | 0.0261675 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0256607 |
| CSRP1 | cysteine and glycine-rich protein 1 | 0.0246719 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0246496 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0243773 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0241488 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0240959 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0237974 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0236765 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0236278 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0234309 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0233135 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0230485 |
| CD109 | CD109 molecule | 0.0223103 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0218463 |
| DNER | delta/notch-like EGF repeat containing | 0.0217892 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0212341 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | 0.0211858 |
| GPRIN3 | GPRIN family member 3 | 0.0208528 |
| MSN | moesin | 0.0206215 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0206155 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.020598 |
| LAMA5 | laminin, alpha 5 | 0.0204423 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0203447 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0202882 |
| FAM219A | family with sequence similarity 219, member A | 0.020173 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0199694 |
| BMP6 | bone morphogenetic protein 6 | 0.0198713 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0194785 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0194268 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0191999 |
| ATP13A3 | ATPase type 13A3 | 0.0189938 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0189601 |
| AUTS2 | autism susceptibility candidate 2 | 0.0189144 |
| FAM13A | family with sequence similarity 13, member A | 0.0188667 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0188665 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0187491 |
| PLEC | plectin | 0.0187005 |
| GPC6 | glypican 6 | 0.0184359 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0181501 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0179312 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0179116 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0178663 |
| ATXN1 | ataxin 1 | 0.0177691 |
| DENND3 | DENN/MADD domain containing 3 | 0.0177641 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0175975 |
| CABIN1 | calcineurin binding protein 1 | 0.0175769 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0175118 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0174726 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0174067 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.149796 |
| FN1 | fibronectin 1 | -0.148762 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.137813 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.126891 |
| VIM | vimentin | -0.12167 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0983019 |
| TMSB10 | thymosin beta 10 | -0.0936569 |
| PTMA | prothymosin, alpha | -0.0883197 |
| RPS6 | ribosomal protein S6 | -0.0647286 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0600081 |
| FTL | ferritin, light polypeptide | -0.0590444 |
| CANX | calnexin | -0.0589742 |
| S100A6 | S100 calcium binding protein A6 | -0.056323 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0546335 |
| B2M | beta-2-microglobulin | -0.0494247 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0485129 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0472403 |
| SMYD3 | SET and MYND domain containing 3 | -0.046477 |
| RPLP1 | ribosomal protein, large, P1 | -0.046117 |
| RPL12 | ribosomal protein L12 | -0.0429001 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0428885 |
| RPL31 | ribosomal protein L31 | -0.0427595 |
| RPS8 | ribosomal protein S8 | -0.0413829 |
| RPS24 | ribosomal protein S24 | -0.040609 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0391866 |
| RPLP0 | ribosomal protein, large, P0 | -0.0390213 |
| RPL26 | ribosomal protein L26 | -0.0388985 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0385099 |
| RPL37A | ribosomal protein L37a | -0.0380538 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0360852 |
| HLA-B | major histocompatibility complex, class I, B | -0.0360803 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0358817 |
| RPS3 | ribosomal protein S3 | -0.0354022 |
| RPS23 | ribosomal protein S23 | -0.0346838 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0340705 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0338271 |
| RPS12 | ribosomal protein S12 | -0.0335098 |
| RPS19 | ribosomal protein S19 | -0.0331856 |
| RPL35A | ribosomal protein L35a | -0.0330525 |
| MT2A | metallothionein 2A | -0.0329099 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0322152 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0322059 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0317077 |
| RPL19 | ribosomal protein L19 | -0.0316911 |
| S100A10 | S100 calcium binding protein A10 | -0.031444 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0314425 |
| RPL23 | ribosomal protein L23 | -0.0309594 |
| NCKAP5 | NCK-associated protein 5 | -0.0304869 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0299222 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0295755 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0294834 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0289409 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0285396 |
| SRGN | serglycin | -0.0285117 |
| RPS27A | ribosomal protein S27a | -0.0284448 |
| KIAA0825 | KIAA0825 | -0.0282585 |
| RPLP2 | ribosomal protein, large, P2 | -0.0275943 |
| RPL34 | ribosomal protein L34 | -0.0274304 |
| RPL11 | ribosomal protein L11 | -0.0268161 |
| RPL36A | ribosomal protein L36a | -0.0265941 |
| RPL9 | ribosomal protein L9 | -0.0263106 |
| RPS27 | ribosomal protein S27 | -0.025858 |
| RPS29 | ribosomal protein S29 | -0.0256554 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0252428 |
| RPS14 | ribosomal protein S14 | -0.0250997 |
| RPL7A | ribosomal protein L7a | -0.0247924 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0245438 |
| RGS2 | regulator of G-protein signaling 2 | -0.0242637 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0242238 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0239362 |
| RPL36 | ribosomal protein L36 | -0.0235069 |
| ENO1 | enolase 1, (alpha) | -0.0234114 |
| RPS25 | ribosomal protein S25 | -0.0222994 |
| GNAS | GNAS complex locus | -0.0219281 |
| RPL37 | ribosomal protein L37 | -0.0218938 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0218011 |
| VDAC1 | voltage-dependent anion channel 1 | -0.021795 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0216762 |
| BPTF | bromodomain PHD finger transcription factor | -0.0214899 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0214214 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0213854 |
| RPS16 | ribosomal protein S16 | -0.0212851 |
| STC1 | stanniocalcin 1 | -0.0211331 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0208578 |
| RPL35 | ribosomal protein L35 | -0.0203803 |
| RPS13 | ribosomal protein S13 | -0.0201678 |
| CUX1 | cut-like homeobox 1 | -0.0201229 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0196445 |
| RPS21 | ribosomal protein S21 | -0.0195999 |
| ASTN2 | astrotactin 2 | -0.0192609 |
| RPL32 | ribosomal protein L32 | -0.019172 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0188698 |
| TBCA | tubulin folding cofactor A | -0.0185337 |
| TXNRD1 | thioredoxin reductase 1 | -0.0185073 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0183373 |
| HLA-A | major histocompatibility complex, class I, A | -0.0182932 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0179901 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.017894 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.017853 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.0173884 |
