| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fluvoxamine_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TSC22D2 | TSC22 domain family, member 2 | 0.0969508 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0816878 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0671928 |
| RPL3 | ribosomal protein L3 | 0.0667751 |
| ENAH | enabled homolog (Drosophila) | 0.0635186 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0588754 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0581271 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0568074 |
| PEG10 | paternally expressed 10 | 0.0517278 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0514688 |
| PLPP1 | phospholipid phosphatase 1 | 0.0504792 |
| HDAC9 | histone deacetylase 9 | 0.0503823 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0483745 |
| NCKAP1 | NCK-associated protein 1 | 0.0476635 |
| NTM | neurotrimin | 0.0476309 |
| ITGAV | integrin, alpha V | 0.0467599 |
| WDR43 | WD repeat domain 43 | 0.0461506 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0454508 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0447016 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0446222 |
| RBM20 | RNA binding motif protein 20 | 0.0444548 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0443902 |
| THBS1 | thrombospondin 1 | 0.0438254 |
| GPC3 | glypican 3 | 0.0426059 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.041878 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0418496 |
| PRTG | protogenin | 0.04169 |
| DST | dystonin | 0.0405886 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0405407 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0403749 |
| MED13L | mediator complex subunit 13-like | 0.0397392 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0394904 |
| PGK1 | phosphoglycerate kinase 1 | 0.0394318 |
| ZNF292 | zinc finger protein 292 | 0.0382657 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0382294 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0381504 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0373058 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0366771 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0364018 |
| RPL5 | ribosomal protein L5 | 0.0360631 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0358568 |
| COL5A2 | collagen, type V, alpha 2 | 0.0356327 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0353749 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0352752 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0351533 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0351037 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0347206 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0346037 |
| ACTN4 | actinin, alpha 4 | 0.0345462 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0340669 |
| FLNA | filamin A, alpha | 0.0339467 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.033895 |
| CDC73 | cell division cycle 73 | 0.0338312 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0337615 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0337557 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.033494 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0332727 |
| NONO | non-POU domain containing, octamer-binding | 0.0332605 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0332309 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0329458 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0327052 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0323696 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0318675 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0313487 |
| FUS | FUS RNA binding protein | 0.0313384 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0309351 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0308573 |
| MEMO1 | mediator of cell motility 1 | 0.0302023 |
| PAPOLA | poly(A) polymerase alpha | 0.0295239 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0293142 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.028935 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 0.0287274 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0285873 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.0285601 |
| GASK1B | golgi associated kinase 1B | 0.0284329 |
| GSE1 | Gse1 coiled-coil protein | 0.0284095 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0282757 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0281541 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.0281335 |
| KIF1B | kinesin family member 1B | 0.0280542 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0280491 |
| FAM168B | family with sequence similarity 168, member B | 0.0279781 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0279686 |
| USP3 | ubiquitin specific peptidase 3 | 0.0276451 |
| MTCL1 | microtubule crosslinking factor 1 | 0.027023 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0270113 |
| MED12L | mediator complex subunit 12-like | 0.026864 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0268281 |
| NUP58 | nucleoporin 58 | 0.026768 |
| RPL4 | ribosomal protein L4 | 0.0267341 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0267265 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0263158 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0258924 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.025848 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0254149 |
| MTF2 | metal response element binding transcription factor 2 | 0.0253302 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0251351 |
| ANXA1 | annexin A1 | 0.0250332 |
| APP | amyloid beta (A4) precursor protein | 0.0249434 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0248058 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.126084 |
| PTMA | prothymosin, alpha | -0.115539 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.099964 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0922979 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0910674 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0899281 |
| TMSB10 | thymosin beta 10 | -0.0684605 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0664658 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0654806 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0633607 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0591614 |
| RPS16 | ribosomal protein S16 | -0.0558553 |
| RPLP1 | ribosomal protein, large, P1 | -0.0549841 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0487599 |
| RPS8 | ribosomal protein S8 | -0.0480696 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0463635 |
| CENPF | centromere protein F, 350/400kDa | -0.0455113 |
| RPLP0 | ribosomal protein, large, P0 | -0.0453121 |
| FTL | ferritin, light polypeptide | -0.0432452 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0427934 |
| RPL35A | ribosomal protein L35a | -0.0422002 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0415432 |
| RPL19 | ribosomal protein L19 | -0.041247 |
| HMGB2 | high mobility group box 2 | -0.0404344 |
| SGO2 | shugoshin 2 | -0.0397421 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0377344 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0370315 |
| PFN1 | profilin 1 | -0.0369422 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0362507 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0358801 |
| HMGB1 | high mobility group box 1 | -0.0356906 |
| COL3A1 | collagen, type III, alpha 1 | -0.0346474 |
| RPS19 | ribosomal protein S19 | -0.0341771 |
| RPS21 | ribosomal protein S21 | -0.0341696 |
| NDRG1 | N-myc downstream regulated 1 | -0.0340938 |
| AHNAK | AHNAK nucleoprotein | -0.0336583 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0332875 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0332435 |
| RPL34 | ribosomal protein L34 | -0.0323803 |
| BBX | bobby sox homolog (Drosophila) | -0.0322664 |
| GNAS | GNAS complex locus | -0.0313946 |
| RPL12 | ribosomal protein L12 | -0.0312682 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0306823 |
| RPS24 | ribosomal protein S24 | -0.0304961 |
| RPS25 | ribosomal protein S25 | -0.0304684 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0298558 |
| RPS5 | ribosomal protein S5 | -0.0295183 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.029277 |
| SETD5 | SET domain containing 5 | -0.0290391 |
| RPS6 | ribosomal protein S6 | -0.0288247 |
| MORF4L2 | mortality factor 4 like 2 | -0.0288205 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0284576 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0281722 |
| RPL31 | ribosomal protein L31 | -0.0279132 |
| RPS13 | ribosomal protein S13 | -0.0276472 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0274266 |
| RPS27A | ribosomal protein S27a | -0.0273464 |
| PCDH9 | protocadherin 9 | -0.02705 |
| RPL28 | ribosomal protein L28 | -0.0265759 |
| CENPE | centromere protein E, 312kDa | -0.0262387 |
| TPR | translocated promoter region, nuclear basket protein | -0.025954 |
| HIP1 | huntingtin interacting protein 1 | -0.0259304 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0259152 |
| HMGA1 | high mobility group AT-hook 1 | -0.0255216 |
| B2M | beta-2-microglobulin | -0.0252842 |
| CANX | calnexin | -0.0251923 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0251152 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0250589 |
| ASTN2 | astrotactin 2 | -0.0242831 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.024085 |
| AK1 | adenylate kinase 1 | -0.0240044 |
| MED13 | mediator complex subunit 13 | -0.0238482 |
| ASPH | aspartate beta-hydroxylase | -0.0238396 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0236233 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0235105 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.023463 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0233564 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0233055 |
| MKI67 | marker of proliferation Ki-67 | -0.0231702 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0230917 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0229905 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | -0.0229775 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0229419 |
| RPL26 | ribosomal protein L26 | -0.0229398 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0227524 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -0.0227452 |
| PRR11 | proline rich 11 | -0.0227205 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0226774 |
| RTN3 | reticulon 3 | -0.0226168 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0225791 |
| TUBA1B | tubulin, alpha 1b | -0.0223996 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0223536 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0223477 |
| RPS11 | ribosomal protein S11 | -0.0219007 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0218264 |
| TUT4 | terminal uridylyl transferase 4 | -0.021811 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0217809 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0217048 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0216719 |
| BPTF | bromodomain PHD finger transcription factor | -0.0215694 |
