Fluvoxamine_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Fluvoxamine perturbation in SNU-1 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Fluvoxamine_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FLNB filamin B, beta 0.0782284
PYGB phosphorylase, glycogen; brain 0.0623285
CAMTA1 calmodulin binding transcription activator 1 0.0561921
SOX6 SRY (sex determining region Y)-box 6 0.046439
PRELID2 PRELI domain containing 2 0.0461789
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0437812
RPL3 ribosomal protein L3 0.0416643
ADAM10 ADAM metallopeptidase domain 10 0.0399329
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0399292
GLI2 GLI family zinc finger 2 0.0386087
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0384838
TJP1 tight junction protein 1 0.0379887
NBAS neuroblastoma amplified sequence 0.0370785
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 0.0360457
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.03546
PDGFC platelet derived growth factor C 0.0337128
EGFR epidermal growth factor receptor 0.033216
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0331138
TBC1D22A TBC1 domain family, member 22A 0.0329885
ZEB1 zinc finger E-box binding homeobox 1 0.0329464
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0329188
PDE4B phosphodiesterase 4B, cAMP-specific 0.0316656
DSCAM Down syndrome cell adhesion molecule 0.0310209
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0308852
LPP LIM domain containing preferred translocation partner in lipoma 0.0307501
TMEM65 transmembrane protein 65 0.0305433
KDM3A lysine (K)-specific demethylase 3A 0.0303603
TGFBR3 transforming growth factor, beta receptor III 0.0300365
HDAC9 histone deacetylase 9 0.0299865
MSI2 musashi RNA-binding protein 2 0.0297568
VCL vinculin 0.0293779
AHNAK AHNAK nucleoprotein 0.0292139
PLXNA1 plexin A1 0.0291304
SMYD3 SET and MYND domain containing 3 0.0286859
PICALM phosphatidylinositol binding clathrin assembly protein 0.0285286
YEATS2 YEATS domain containing 2 0.0271754
SAMD4A sterile alpha motif domain containing 4A 0.0265643
PDE4D phosphodiesterase 4D, cAMP-specific 0.0258159
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0249389
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0248713
ZNF292 zinc finger protein 292 0.0237894
NBEA neurobeachin 0.0234452
ZMIZ1 zinc finger, MIZ-type containing 1 0.0231719
EML4 echinoderm microtubule associated protein like 4 0.0231289
DENND1A DENN/MADD domain containing 1A 0.0226606
GSE1 Gse1 coiled-coil protein 0.0221677
SBF2 SET binding factor 2 0.0220835
SREBF2 sterol regulatory element binding transcription factor 2 0.0218005
JMJD1C jumonji domain containing 1C 0.021177
PIWIL1 piwi-like RNA-mediated gene silencing 1 0.0211411
EIF4A2 eukaryotic translation initiation factor 4A2 0.02106
NUP58 nucleoporin 58 0.0204759
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0203603
CDC73 cell division cycle 73 0.0199991
GSK3B glycogen synthase kinase 3 beta 0.019896
FHIT fragile histidine triad 0.0198118
LOXL3 lysyl oxidase-like 3 0.0192342
IGF1R insulin-like growth factor 1 receptor 0.0191444
MYOF myoferlin 0.0191027
FAT1 FAT atypical cadherin 1 0.0190364
ANKRD36 ankyrin repeat domain 36 0.0190001
SFPQ splicing factor proline/glutamine-rich 0.0181991
AMOTL2 angiomotin like 2 0.0181274
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.0180315
TTC28 tetratricopeptide repeat domain 28 0.0180173
ELOVL5 ELOVL fatty acid elongase 5 0.0176665
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0176535
KDM4C lysine (K)-specific demethylase 4C 0.0175765
HDLBP high density lipoprotein binding protein 0.0170877
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 0.0170205
EFNA5 ephrin-A5 0.0169505
KDM6A lysine (K)-specific demethylase 6A 0.0168139
FNIP1 folliculin interacting protein 1 0.0166274
BMP2K BMP2 inducible kinase 0.0163378
FLNA filamin A, alpha 0.0161376
HOOK2 hook microtubule-tethering protein 2 0.0160903
KDM4B lysine (K)-specific demethylase 4B 0.0160393
NCKAP1 NCK-associated protein 1 0.016032
CD47 CD47 molecule 0.016017
CABIN1 calcineurin binding protein 1 0.0158601
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.015725
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.0156813
TENT4A terminal nucleotidyltransferase 4A 0.015581
PTK2 protein tyrosine kinase 2 0.0155662
NFIA nuclear factor I/A 0.0155618
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.0154315
SMAD6 SMAD family member 6 0.0154098
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.015314
CTIF CBP80/20-dependent translation initiation factor 0.015286
TXNRD1 thioredoxin reductase 1 0.0150894
CASC3 cancer susceptibility candidate 3 0.0150068
CNOT1 CCR4-NOT transcription complex, subunit 1 0.0146974
ZMYM2 zinc finger, MYM-type 2 0.0146732
ANKRD11 ankyrin repeat domain 11 0.0146101
DLG1 discs, large homolog 1 (Drosophila) 0.0143282
NCEH1 neutral cholesterol ester hydrolase 1 0.014269
FNDC3B fibronectin type III domain containing 3B 0.0142679
TMEM39A transmembrane protein 39A 0.0140568
AUH AU RNA binding protein/enoyl-CoA hydratase 0.0140098
ADAM9 ADAM metallopeptidase domain 9 0.0139972

decreased expression

Symbol Name Standardized Value
PTMA prothymosin, alpha -0.309436
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.235578
RPS6 ribosomal protein S6 -0.125417
TPT1 tumor protein, translationally-controlled 1 -0.0804696
RPS8 ribosomal protein S8 -0.079372
RPL35A ribosomal protein L35a -0.0698311
S100A6 S100 calcium binding protein A6 -0.0690125
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0678435
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0660807
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0607227
RPLP1 ribosomal protein, large, P1 -0.0605807
ACTG1 actin gamma 1 -0.0590195
RPL34 ribosomal protein L34 -0.0555518
RPS19 ribosomal protein S19 -0.0546394
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0531772
RPL12 ribosomal protein L12 -0.0519629
RPL31 ribosomal protein L31 -0.0507761
RPLP0 ribosomal protein, large, P0 -0.0495828
RPL26 ribosomal protein L26 -0.0487116
RPLP2 ribosomal protein, large, P2 -0.0465296
RPL11 ribosomal protein L11 -0.0465264
RPL19 ribosomal protein L19 -0.0463171
RPS23 ribosomal protein S23 -0.0455954
RPS3 ribosomal protein S3 -0.0440026
EIF1 eukaryotic translation initiation factor 1 -0.0439025
PFN1 profilin 1 -0.0436997
RPS13 ribosomal protein S13 -0.0396417
B2M beta-2-microglobulin -0.0395908
RPS12 ribosomal protein S12 -0.0394564
RPL23 ribosomal protein L23 -0.039218
RPL9 ribosomal protein L9 -0.038755
TMSB4X thymosin beta 4, X-linked -0.0387018
RPL37A ribosomal protein L37a -0.0377344
RPL36 ribosomal protein L36 -0.0375938
RPS25 ribosomal protein S25 -0.036637
RPS27A ribosomal protein S27a -0.036179
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0360596
HSPB1 heat shock 27kDa protein 1 -0.0360481
S100A9 S100 calcium binding protein A9 -0.0359816
FTL ferritin, light polypeptide -0.0355039
RPL7A ribosomal protein L7a -0.0329755
TMSB10 thymosin beta 10 -0.0328852
RPL32 ribosomal protein L32 -0.0324195
MT2A metallothionein 2A -0.0320221
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0312929
PKM pyruvate kinase, muscle -0.0310799
RPS29 ribosomal protein S29 -0.0307878
S100A4 S100 calcium binding protein A4 -0.0298905
RPL28 ribosomal protein L28 -0.0297978
RPS14 ribosomal protein S14 -0.0288611
RPL8 ribosomal protein L8 -0.0284602
RPS21 ribosomal protein S21 -0.0283264
NAP1L1 nucleosome assembly protein 1-like 1 -0.0279447
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0276827
RPL7 ribosomal protein L7 -0.0275095
RPL27A ribosomal protein L27a -0.0271144
ARL4C ADP-ribosylation factor-like 4C -0.0268445
RPL13A ribosomal protein L13a -0.0267843
S100A10 S100 calcium binding protein A10 -0.0263173
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0263013
POTEF POTE ankyrin domain family, member F -0.0262782
PRDX2 peroxiredoxin 2 -0.0259208
RPS27 ribosomal protein S27 -0.0253316
RPS16 ribosomal protein S16 -0.0251452
RPS24 ribosomal protein S24 -0.0241635
EEF1G eukaryotic translation elongation factor 1 gamma -0.0239962
RPL5 ribosomal protein L5 -0.0238048
RPL35 ribosomal protein L35 -0.0234668
HMGA1 high mobility group AT-hook 1 -0.0234318
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0233128
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0228641
RPL18 ribosomal protein L18 -0.0226212
PDIA3 protein disulfide isomerase family A, member 3 -0.0223363
GNAS GNAS complex locus -0.0221841
RACK1 receptor for activated C kinase 1 -0.0220249
MYL12B myosin, light chain 12B, regulatory -0.0219239
RPS2 ribosomal protein S2 -0.0217177
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.021642
RPS5 ribosomal protein S5 -0.0215731
RPS10 ribosomal protein S10 -0.0214558
RPS11 ribosomal protein S11 -0.0209713
RPS17 ribosomal protein S17 -0.0207394
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0206539
ANXA1 annexin A1 -0.0201886
RSL1D1 ribosomal L1 domain containing 1 -0.0198656
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0197855
ATF4 activating transcription factor 4 -0.0197572
RPS15 ribosomal protein S15 -0.0195092
LDHA lactate dehydrogenase A -0.0194856
RPL30 ribosomal protein L30 -0.01916
RPL37 ribosomal protein L37 -0.0188762
RPL36A ribosomal protein L36a -0.0188487
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.0187024
UQCRB ubiquinol-cytochrome c reductase binding protein -0.0186324
GARS1 glycyl-tRNA synthetase 1 -0.0182546
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.0182295
RPS4X ribosomal protein S4, X-linked -0.0181711
RPS20 ribosomal protein S20 -0.0180264
LOC102724023 ES1 protein homolog, mitochondrial -0.0174868
DUSP6 dual specificity phosphatase 6 -0.0172685