| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fluvoxamine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUP58 | nucleoporin 58 | 0.0362047 |
| MIS18BP1 | MIS18 binding protein 1 | 0.033414 |
| MKI67 | marker of proliferation Ki-67 | 0.0330319 |
| HJURP | Holliday junction recognition protein | 0.0314062 |
| SMAD3 | SMAD family member 3 | 0.0313743 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0307668 |
| NAV2 | neuron navigator 2 | 0.0298955 |
| TUBB | tubulin, beta class I | 0.0273211 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0273147 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0258959 |
| HELZ | helicase with zinc finger | 0.0250179 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0246983 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0245056 |
| FLNA | filamin A, alpha | 0.0244504 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0242853 |
| CKAP2L | cytoskeleton associated protein 2-like | 0.0240662 |
| CEP250 | centrosomal protein 250kDa | 0.0240658 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0234699 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0232431 |
| BRD8 | bromodomain containing 8 | 0.0230504 |
| DNER | delta/notch-like EGF repeat containing | 0.0227434 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0226629 |
| ATP13A3 | ATPase type 13A3 | 0.0220906 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0220691 |
| CDYL | chromodomain protein, Y-like | 0.0219332 |
| ANLN | anillin, actin binding protein | 0.0217781 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0215694 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0214699 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.0214398 |
| MSN | moesin | 0.0208122 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0208078 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0207577 |
| YAP1 | Yes-associated protein 1 | 0.0205198 |
| SEC24A | SEC24 family member A | 0.0202587 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.020227 |
| PANX1 | pannexin 1 | 0.0202149 |
| NGLY1 | N-glycanase 1 | 0.0201617 |
| RBM26 | RNA binding motif protein 26 | 0.0201385 |
| SPAG5 | sperm associated antigen 5 | 0.0200581 |
| CEP70 | centrosomal protein 70kDa | 0.0197209 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0196195 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0195745 |
| TBK1 | TANK-binding kinase 1 | 0.0192614 |
| SGO2 | shugoshin 2 | 0.0190904 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0189103 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.018902 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0188856 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0187752 |
| FUBP3 | far upstream element (FUSE) binding protein 3 | 0.0186354 |
| AFTPH | aftiphilin | 0.0186224 |
| YEATS2 | YEATS domain containing 2 | 0.0186136 |
| CENPE | centromere protein E, 312kDa | 0.0181033 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0179184 |
| PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit | 0.0178707 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.017836 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0177342 |
| AFDN | afadin, adherens junction formation factor | 0.0177301 |
| FAM168A | family with sequence similarity 168, member A | 0.0176986 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0176979 |
| RNF145 | ring finger protein 145 | 0.0175487 |
| MED17 | mediator complex subunit 17 | 0.0173893 |
| TPM3 | tropomyosin 3 | 0.0173678 |
| RPL3 | ribosomal protein L3 | 0.0172703 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0171883 |
| UBAC2 | UBA domain containing 2 | 0.0171813 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0170644 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0169514 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0169038 |
| NEK6 | NIMA-related kinase 6 | 0.0168681 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0167344 |
| POM121 | POM121 transmembrane nucleoporin | 0.0167294 |
| DIDO1 | death inducer-obliterator 1 | 0.0166479 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0165905 |
| CCNG2 | cyclin G2 | 0.0165903 |
| TET3 | tet methylcytosine dioxygenase 3 | 0.016589 |
| DMXL2 | Dmx-like 2 | 0.0165751 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0165094 |
| TPX2 | TPX2, microtubule-associated | 0.0164996 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0164752 |
| SEPTIN2 | septin 2 | 0.0164053 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0163177 |
| CDC42SE2 | CDC42 small effector 2 | 0.0163087 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0162875 |
| NCKAP1 | NCK-associated protein 1 | 0.0162717 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0162563 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0162339 |
| LMNB1 | lamin B1 | 0.0161131 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0160724 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0158032 |
| AURKA | aurora kinase A | 0.0157365 |
| RNF40 | ring finger protein 40, E3 ubiquitin protein ligase | 0.0157022 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0156657 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0156447 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0155274 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0154665 |
| SRP54 | signal recognition particle 54kDa | 0.0153538 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0153035 |
| NONO | non-POU domain containing, octamer-binding | 0.0153018 |
| KIF3A | kinesin family member 3A | 0.0152456 |
| H1-4 | H1.4 linker histone, cluster member | 0.0152329 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.412597 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.169675 |
| VIM | vimentin | -0.15088 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.1298 |
| TMSB10 | thymosin beta 10 | -0.123183 |
| PTMA | prothymosin, alpha | -0.117263 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.102607 |
| LDHA | lactate dehydrogenase A | -0.100299 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0871172 |
| HMGA2 | high mobility group AT-hook 2 | -0.077324 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0758357 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0750292 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.071317 |
| AHNAK | AHNAK nucleoprotein | -0.0696837 |
| PRKCA | protein kinase C, alpha | -0.0606454 |
| INTS6 | integrator complex subunit 6 | -0.0574871 |
| CANX | calnexin | -0.057034 |
| ANXA2 | annexin A2 | -0.056081 |
| CD44 | CD44 molecule (Indian blood group) | -0.0556324 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0552716 |
| POTEF | POTE ankyrin domain family, member F | -0.0515694 |
| RAI14 | retinoic acid induced 14 | -0.0514915 |
| SDC4 | syndecan 4 | -0.0513717 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0511191 |
| ENO1 | enolase 1, (alpha) | -0.0497057 |
| S100A10 | S100 calcium binding protein A10 | -0.0485798 |
| GNAS | GNAS complex locus | -0.0464715 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0456899 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0455704 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0455035 |
| RIGI | RNA sensor RIG-I | -0.0441023 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.043798 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0425676 |
| NF1 | neurofibromin 1 | -0.0421909 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0417755 |
| RPLP1 | ribosomal protein, large, P1 | -0.0416859 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0413516 |
| ASPH | aspartate beta-hydroxylase | -0.0408791 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0407361 |
| UBC | ubiquitin C | -0.0401375 |
| SQSTM1 | sequestosome 1 | -0.0400789 |
| RPS8 | ribosomal protein S8 | -0.0397061 |
| S100A9 | S100 calcium binding protein A9 | -0.0393213 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0392248 |
| PKM | pyruvate kinase, muscle | -0.038787 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0386744 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0386736 |
| ACTG1 | actin gamma 1 | -0.0383785 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0382265 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0381187 |
| ANGPTL4 | angiopoietin-like 4 | -0.0377919 |
| RPL31 | ribosomal protein L31 | -0.0377593 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0377404 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0377345 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0369626 |
| SETX | senataxin | -0.0362455 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0355793 |
| EGR1 | early growth response 1 | -0.0354588 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.035067 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0350429 |
| RTN4 | reticulon 4 | -0.0347449 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0345234 |
| RPLP0 | ribosomal protein, large, P0 | -0.0342322 |
| DST | dystonin | -0.0335299 |
| TAOK1 | TAO kinase 1 | -0.0327977 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0326926 |
| RPS27A | ribosomal protein S27a | -0.0324419 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0322479 |
| PODXL | podocalyxin-like | -0.0321957 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0321552 |
| B2M | beta-2-microglobulin | -0.0320812 |
| PRRC2C | proline-rich coiled-coil 2C | -0.031535 |
| ATM | ATM serine/threonine kinase | -0.03137 |
| FTL | ferritin, light polypeptide | -0.0308101 |
| RPS6 | ribosomal protein S6 | -0.0306985 |
| RPL34 | ribosomal protein L34 | -0.0305736 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0304854 |
| CAVIN1 | caveolae associated protein 1 | -0.0303169 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0297239 |
| FLNB | filamin B, beta | -0.0297205 |
| MYO9A | myosin IXA | -0.0296639 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0296197 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.029598 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0295674 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0293187 |
| RPL35A | ribosomal protein L35a | -0.0290934 |
| MT2A | metallothionein 2A | -0.0287435 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0279702 |
| TPI1 | triosephosphate isomerase 1 | -0.0279592 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0278337 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0277568 |
| RPS3 | ribosomal protein S3 | -0.0277349 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0275884 |
| SVIL | supervillin | -0.0274294 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0272585 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0272525 |
| MYOF | myoferlin | -0.0271889 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0271816 |
| JUN | jun proto-oncogene | -0.0269413 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0268595 |
