| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Folic acid perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Folic acid_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | 0.241028 |
| PCDH7 | protocadherin 7 | 0.117002 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.110019 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.109346 |
| YAP1 | Yes-associated protein 1 | 0.10251 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0988599 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0884917 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0831623 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0709453 |
| HMGA2 | high mobility group AT-hook 2 | 0.0701497 |
| VIM | vimentin | 0.0697536 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0682017 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0668423 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0598993 |
| NEBL | nebulette | 0.0544383 |
| ANXA1 | annexin A1 | 0.053334 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0530288 |
| TENM3 | teneurin transmembrane protein 3 | 0.052329 |
| AHNAK | AHNAK nucleoprotein | 0.0450364 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0447289 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0424704 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.041559 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0415255 |
| ADIPOR2 | adiponectin receptor 2 | 0.0401529 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0398713 |
| CCND1 | cyclin D1 | 0.0395928 |
| PCDH9 | protocadherin 9 | 0.0395723 |
| INTS6 | integrator complex subunit 6 | 0.0391546 |
| ACTG1 | actin gamma 1 | 0.0368879 |
| EDARADD | EDAR-associated death domain | 0.0368112 |
| PRR16 | proline rich 16 | 0.0338102 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0337998 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0336026 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0329237 |
| MKI67 | marker of proliferation Ki-67 | 0.0324495 |
| DST | dystonin | 0.0323459 |
| RASAL2 | RAS protein activator like 2 | 0.0309368 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0304029 |
| H1-0 | H1.0 linker histone | 0.0302892 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0300615 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.029112 |
| ECT2 | epithelial cell transforming 2 | 0.0280394 |
| MTAP | methylthioadenosine phosphorylase | 0.0278396 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0274215 |
| ETV6 | ets variant 6 | 0.0270311 |
| ENO1 | enolase 1, (alpha) | 0.0264339 |
| RRM2 | ribonucleotide reductase M2 | 0.0261733 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0257325 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0252423 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0245845 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.024206 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0237687 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0237096 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0235351 |
| PDGFC | platelet derived growth factor C | 0.0227851 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0227539 |
| RNF213 | ring finger protein 213 | 0.0224822 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.0222438 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0217739 |
| TMEM123 | transmembrane protein 123 | 0.021668 |
| CEP112 | centrosomal protein 112kDa | 0.0215447 |
| INTS4 | integrator complex subunit 4 | 0.0215071 |
| LATS2 | large tumor suppressor kinase 2 | 0.0213202 |
| SSH2 | slingshot protein phosphatase 2 | 0.0208657 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0208457 |
| TMEM181 | transmembrane protein 181 | 0.0206331 |
| NFIB | nuclear factor I/B | 0.0205771 |
| UTRN | utrophin | 0.0205296 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.020492 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0203467 |
| FUS | FUS RNA binding protein | 0.0200413 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0199632 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0199612 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0197754 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.0196784 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0195407 |
| ACBD6 | acyl-CoA binding domain containing 6 | 0.0194226 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0193942 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0193336 |
| CMIP | c-Maf inducing protein | 0.0193155 |
| GPATCH8 | G patch domain containing 8 | 0.0192537 |
| FLNA | filamin A, alpha | 0.0187911 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0187684 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0187513 |
| EGR1 | early growth response 1 | 0.0186822 |
| PRELID2 | PRELI domain containing 2 | 0.0185295 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0184316 |
| RCOR1 | REST corepressor 1 | 0.0183804 |
| EPHA6 | EPH receptor A6 | 0.018188 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0181707 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0181522 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.018149 |
| PRDX1 | peroxiredoxin 1 | 0.0181248 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0180073 |
| MYPN | myopalladin | 0.0179715 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0179247 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.017891 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0178532 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0176392 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0175379 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | -0.116188 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0727919 |
| RPS2 | ribosomal protein S2 | -0.0597736 |
| RPS6 | ribosomal protein S6 | -0.0592999 |
| TXNRD1 | thioredoxin reductase 1 | -0.0566232 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0492343 |
| RPS12 | ribosomal protein S12 | -0.0488739 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0485883 |
| GOLGA4 | golgin A4 | -0.0463259 |
| RPS8 | ribosomal protein S8 | -0.0452076 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0450449 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0440979 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0435285 |
| BCHE | butyrylcholinesterase | -0.0433433 |
| RTN4 | reticulon 4 | -0.0417577 |
| FTL | ferritin, light polypeptide | -0.0379641 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0379338 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0376764 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0374313 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0372377 |
| RPS13 | ribosomal protein S13 | -0.0369353 |
| RPL23 | ribosomal protein L23 | -0.0336547 |
| RPL12 | ribosomal protein L12 | -0.0328986 |
| PCBP2 | poly(rC) binding protein 2 | -0.0327119 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0324884 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0318846 |
| RPLP2 | ribosomal protein, large, P2 | -0.0309015 |
| RPL11 | ribosomal protein L11 | -0.030896 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0299667 |
| RPS23 | ribosomal protein S23 | -0.029681 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0293605 |
| WASF2 | WAS protein family, member 2 | -0.0278225 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0274402 |
| RPL19 | ribosomal protein L19 | -0.027267 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.0271373 |
| RPL37A | ribosomal protein L37a | -0.0270772 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0269712 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0268265 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0259185 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.025679 |
| KIF5B | kinesin family member 5B | -0.025071 |
| SBF2 | SET binding factor 2 | -0.0250447 |
| RPS19 | ribosomal protein S19 | -0.024632 |
| KLHL24 | kelch-like family member 24 | -0.0244265 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0237841 |
| RPL8 | ribosomal protein L8 | -0.0234156 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0232939 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0231974 |
| YBX3 | Y box binding protein 3 | -0.023131 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0229233 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0226757 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0226139 |
| YBX1 | Y box binding protein 1 | -0.0224717 |
| RPS27A | ribosomal protein S27a | -0.0217386 |
| SET | SET nuclear proto-oncogene | -0.0215904 |
| RNF13 | ring finger protein 13 | -0.0215214 |
| RPL26 | ribosomal protein L26 | -0.0214897 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -0.021384 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0213339 |
| CLTC | clathrin, heavy chain (Hc) | -0.0207466 |
| HM13 | histocompatibility (minor) 13 | -0.0206199 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.020545 |
| RPL36 | ribosomal protein L36 | -0.0204886 |
| RPS29 | ribosomal protein S29 | -0.0203982 |
| TMEM167A | transmembrane protein 167A | -0.0203236 |
| ATAD2B | ATPase family, AAA domain containing 2B | -0.0201979 |
| TNPO1 | transportin 1 | -0.0200409 |
| METTL15 | methyltransferase like 15 | -0.0198321 |
| RPL9 | ribosomal protein L9 | -0.0197821 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0197651 |
| SMC6 | structural maintenance of chromosomes 6 | -0.0196577 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0194595 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0194032 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0192722 |
| RPL7 | ribosomal protein L7 | -0.0190133 |
| COG5 | component of oligomeric golgi complex 5 | -0.0189622 |
| KLC1 | kinesin light chain 1 | -0.0186694 |
| NKTR | natural killer cell triggering receptor | -0.0185744 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0185056 |
| NEK7 | NIMA-related kinase 7 | -0.0184296 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0184268 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0183809 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0183611 |
| EDN1 | endothelin 1 | -0.0182338 |
| THOC1 | THO complex 1 | -0.018231 |
| RPLP0 | ribosomal protein, large, P0 | -0.0182155 |
| RPL34 | ribosomal protein L34 | -0.0181015 |
| HLA-A | major histocompatibility complex, class I, A | -0.0180005 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0179319 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | -0.017856 |
| HEATR5B | HEAT repeat containing 5B | -0.0177934 |
| EXOC6 | exocyst complex component 6 | -0.0177508 |
| PAPOLA | poly(A) polymerase alpha | -0.0176146 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0176049 |
| PREPL | prolyl endopeptidase-like | -0.0175163 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0174605 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0174461 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0174223 |
| RPL27 | ribosomal protein L27 | -0.0174082 |
| RPS3 | ribosomal protein S3 | -0.0174033 |
