| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Folic acid perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Folic acid_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.195603 |
| EFNA5 | ephrin-A5 | 0.121294 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0868694 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.082214 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0807813 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0785691 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0749876 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0708176 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0686077 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.068372 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0673093 |
| PDE10A | phosphodiesterase 10A | 0.0642778 |
| CA12 | carbonic anhydrase XII | 0.0627243 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0597287 |
| FLNB | filamin B, beta | 0.0557241 |
| SMAD3 | SMAD family member 3 | 0.0555286 |
| AXL | AXL receptor tyrosine kinase | 0.0506457 |
| MCL1 | myeloid cell leukemia 1 | 0.0503682 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0502431 |
| MSN | moesin | 0.0500375 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0484536 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0453189 |
| CMIP | c-Maf inducing protein | 0.0442579 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0440523 |
| NDRG1 | N-myc downstream regulated 1 | 0.0417897 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0404104 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.03997 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0376601 |
| MYADM | myeloid-associated differentiation marker | 0.0371698 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0371676 |
| RIN2 | Ras and Rab interactor 2 | 0.0368612 |
| TGM2 | transglutaminase 2 | 0.0363273 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0351499 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0341715 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0334894 |
| TXNRD1 | thioredoxin reductase 1 | 0.03225 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0322265 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0313138 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0311925 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0307862 |
| C1D | C1D nuclear receptor corepressor | 0.0307239 |
| PCBP2 | poly(rC) binding protein 2 | 0.0306689 |
| BCL2L1 | BCL2-like 1 | 0.0306249 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0304407 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0299209 |
| OSMR | oncostatin M receptor | 0.0297218 |
| MAP1B | microtubule-associated protein 1B | 0.0296622 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0296529 |
| FAM107B | family with sequence similarity 107, member B | 0.0290127 |
| NRP1 | neuropilin 1 | 0.0284364 |
| RTN4 | reticulon 4 | 0.0282043 |
| EHBP1 | EH domain binding protein 1 | 0.0276269 |
| TNS1 | tensin 1 | 0.0271118 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0269137 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0263685 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0260992 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0252675 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0250641 |
| RPL3 | ribosomal protein L3 | 0.0240955 |
| MLKL | mixed lineage kinase domain-like | 0.0239822 |
| ZFP36 | ZFP36 ring finger protein | 0.0239589 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0239387 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0232264 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0231823 |
| RUNX1 | runt-related transcription factor 1 | 0.0230729 |
| FAM13A | family with sequence similarity 13, member A | 0.0229572 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0226485 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0223827 |
| DOCK5 | dedicator of cytokinesis 5 | 0.022372 |
| WWC1 | WW and C2 domain containing 1 | 0.0217759 |
| AOPEP | aminopeptidase O (putative) | 0.0214254 |
| PFKP | phosphofructokinase, platelet | 0.0211831 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0209749 |
| SMYD3 | SET and MYND domain containing 3 | 0.0209058 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0208045 |
| EXOC6B | exocyst complex component 6B | 0.0207521 |
| CEP170 | centrosomal protein 170kDa | 0.0205813 |
| SIN3A | SIN3 transcription regulator family member A | 0.0202192 |
| DENND4C | DENN/MADD domain containing 4C | 0.0201569 |
| EZR | ezrin | 0.0200731 |
| RAI14 | retinoic acid induced 14 | 0.0200026 |
| ITGB5 | integrin, beta 5 | 0.0199951 |
| PHF21A | PHD finger protein 21A | 0.0197004 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0190986 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0188714 |
| SRPK2 | SRSF protein kinase 2 | 0.0188533 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0185896 |
| LAMA5 | laminin, alpha 5 | 0.0182772 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0182443 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0180393 |
| GRAMD1B | GRAM domain containing 1B | 0.0179693 |
| NGLY1 | N-glycanase 1 | 0.0179255 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0178552 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0178413 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0177818 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0175264 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0173207 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0172982 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0171586 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0170659 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.184214 |
| ACTG1 | actin gamma 1 | -0.131566 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.128863 |
| VCL | vinculin | -0.107805 |
| FTL | ferritin, light polypeptide | -0.103902 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.103078 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0942903 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0884904 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0867801 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0839624 |
| INTS6 | integrator complex subunit 6 | -0.0726161 |
| VIM | vimentin | -0.0712919 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0678008 |
| RPS24 | ribosomal protein S24 | -0.0663064 |
| RPLP1 | ribosomal protein, large, P1 | -0.0645194 |
| SP100 | SP100 nuclear antigen | -0.0623306 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0616929 |
| NCOA7 | nuclear receptor coactivator 7 | -0.05739 |
| AADAC | arylacetamide deacetylase | -0.0567776 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0563558 |
| AHNAK | AHNAK nucleoprotein | -0.0561466 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0558455 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0547799 |
| RPS6 | ribosomal protein S6 | -0.0541159 |
| SQSTM1 | sequestosome 1 | -0.0541036 |
| PALLD | palladin, cytoskeletal associated protein | -0.0536726 |
| KYNU | kynureninase | -0.0532608 |
| RPS19 | ribosomal protein S19 | -0.0518331 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0511068 |
| RPL23 | ribosomal protein L23 | -0.0509758 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0507698 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0506592 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0505768 |
| LDHA | lactate dehydrogenase A | -0.0505244 |
| RPL26 | ribosomal protein L26 | -0.0481766 |
| RPS8 | ribosomal protein S8 | -0.0463241 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0451187 |
| PTMA | prothymosin, alpha | -0.0447808 |
| RPL12 | ribosomal protein L12 | -0.0444651 |
| FBXO11 | F-box protein 11 | -0.0437259 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0427526 |
| RPS16 | ribosomal protein S16 | -0.0423518 |
| KRT81 | keratin 81, type II | -0.0420389 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.041941 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0413925 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0410916 |
| RIGI | RNA sensor RIG-I | -0.0403568 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0396922 |
| RPS27A | ribosomal protein S27a | -0.0387482 |
| S100A10 | S100 calcium binding protein A10 | -0.0383785 |
| RPL19 | ribosomal protein L19 | -0.0381961 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0379097 |
| IER3 | immediate early response 3 | -0.0365265 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0364599 |
| RPL35A | ribosomal protein L35a | -0.0360698 |
| SPAG9 | sperm associated antigen 9 | -0.0348483 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0347082 |
| USP53 | ubiquitin specific peptidase 53 | -0.033448 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0330628 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0329424 |
| TKT | transketolase | -0.0321456 |
| UBC | ubiquitin C | -0.0315896 |
| RPLP0 | ribosomal protein, large, P0 | -0.0314806 |
| RPL37A | ribosomal protein L37a | -0.0314342 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0314026 |
| RPL9 | ribosomal protein L9 | -0.0313046 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0312477 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0309999 |
| RPL38 | ribosomal protein L38 | -0.0307269 |
| RPL13A | ribosomal protein L13a | -0.0306863 |
| HDLBP | high density lipoprotein binding protein | -0.0303685 |
| MORF4L2 | mortality factor 4 like 2 | -0.0301662 |
| DUSP16 | dual specificity phosphatase 16 | -0.0300433 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.029621 |
| TBCA | tubulin folding cofactor A | -0.0295399 |
| PGK1 | phosphoglycerate kinase 1 | -0.0293302 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0292349 |
| S100A6 | S100 calcium binding protein A6 | -0.0291442 |
| SMAD2 | SMAD family member 2 | -0.0291165 |
| TMSB4X | thymosin beta 4, X-linked | -0.0289942 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0289545 |
| RPL34 | ribosomal protein L34 | -0.0282776 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0282392 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0281792 |
| CTBP2 | C-terminal binding protein 2 | -0.0269241 |
| RPL31 | ribosomal protein L31 | -0.0267377 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.026623 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0265492 |
| KLF6 | Kruppel-like factor 6 | -0.0264462 |
| CANX | calnexin | -0.0263469 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.02617 |
| RRBP1 | ribosome binding protein 1 | -0.0258554 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0252739 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0252666 |
| KRT18 | keratin 18, type I | -0.0251792 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0250079 |
| CAVIN1 | caveolae associated protein 1 | -0.0248715 |
| GOLGB1 | golgin B1 | -0.0248596 |
| ECT2 | epithelial cell transforming 2 | -0.0248523 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0248276 |
