| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Folic acid perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Folic acid_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.165572 |
| MEST | mesoderm specific transcript | 0.148627 |
| PDE10A | phosphodiesterase 10A | 0.0957262 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0904233 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0820225 |
| SEPTIN11 | septin 11 | 0.0741363 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.058106 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0574419 |
| CANX | calnexin | 0.0549538 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.054541 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0507791 |
| PRELID2 | PRELI domain containing 2 | 0.0479651 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0476683 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0457165 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0425702 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0392466 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.038738 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0378033 |
| PDE8A | phosphodiesterase 8A | 0.037678 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0357608 |
| PKM | pyruvate kinase, muscle | 0.035515 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0350372 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0343897 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0342399 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0341582 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | 0.033431 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0332561 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0332178 |
| ATP11A | ATPase, class VI, type 11A | 0.0330126 |
| TXNRD1 | thioredoxin reductase 1 | 0.0330107 |
| NF1 | neurofibromin 1 | 0.0329727 |
| ENO1 | enolase 1, (alpha) | 0.0323185 |
| NDRG1 | N-myc downstream regulated 1 | 0.0320184 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0315625 |
| FAM13A | family with sequence similarity 13, member A | 0.0311853 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0311641 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.0309121 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0308444 |
| TMSB10 | thymosin beta 10 | 0.0307731 |
| MCL1 | myeloid cell leukemia 1 | 0.0298164 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0296873 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0294884 |
| AHNAK | AHNAK nucleoprotein | 0.0293454 |
| SMYD3 | SET and MYND domain containing 3 | 0.0290308 |
| ZNF148 | zinc finger protein 148 | 0.0286786 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0285424 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0283236 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.02827 |
| UBC | ubiquitin C | 0.0277708 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0276035 |
| SEPTIN7 | septin 7 | 0.0275322 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0274993 |
| FN1 | fibronectin 1 | 0.0272453 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0262006 |
| BPTF | bromodomain PHD finger transcription factor | 0.0260128 |
| FNDC3B | fibronectin type III domain containing 3B | 0.025979 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0259202 |
| OGA | O-GlcNAcase | 0.0259009 |
| RPL35A | ribosomal protein L35a | 0.0257676 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0256079 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0255743 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0255038 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0254842 |
| FLNB | filamin B, beta | 0.0253996 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.025107 |
| ZFHX3 | zinc finger homeobox 3 | 0.0250338 |
| YAP1 | Yes-associated protein 1 | 0.0249793 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0247896 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0247744 |
| ANXA2 | annexin A2 | 0.0247155 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0244292 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.024413 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0243614 |
| MYO9A | myosin IXA | 0.0243575 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.024279 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0242063 |
| PTCH1 | patched 1 | 0.0241296 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0241185 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0240723 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0240388 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0239726 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0238089 |
| ANO6 | anoctamin 6 | 0.0237992 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0236112 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0235078 |
| BBX | bobby sox homolog (Drosophila) | 0.0232921 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0231027 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0231002 |
| NCOR2 | nuclear receptor corepressor 2 | 0.023098 |
| ATRNL1 | attractin-like 1 | 0.0229846 |
| TMEM131 | transmembrane protein 131 | 0.0229545 |
| TMSB4X | thymosin beta 4, X-linked | 0.022775 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0224617 |
| DENR | density-regulated protein | 0.0222811 |
| SUCO | SUN domain containing ossification factor | 0.0222786 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.022181 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.02217 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 0.0221649 |
| B3GALNT2 | beta-1,3-N-acetylgalactosaminyltransferase 2 | 0.021849 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0218016 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.107106 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0922628 |
| CENPF | centromere protein F, 350/400kDa | -0.0811509 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0745258 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0714229 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0702916 |
| MB21D2 | Mab-21 domain containing 2 | -0.0689075 |
| ZNF292 | zinc finger protein 292 | -0.0677243 |
| RPS6 | ribosomal protein S6 | -0.0669844 |
| PHF3 | PHD finger protein 3 | -0.062912 |
| RPS19 | ribosomal protein S19 | -0.0553337 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0524744 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0523196 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0516529 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0511177 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0510915 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0505237 |
| JMJD1C | jumonji domain containing 1C | -0.0498217 |
| PHF14 | PHD finger protein 14 | -0.0481635 |
| QKI | QKI, KH domain containing, RNA binding | -0.0437564 |
| MED13L | mediator complex subunit 13-like | -0.0435849 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0429883 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0426857 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0426035 |
| IGF2 | insulin-like growth factor 2 | -0.0422559 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0417914 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0414001 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0409893 |
| RPS24 | ribosomal protein S24 | -0.0390383 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0388017 |
| S100A9 | S100 calcium binding protein A9 | -0.0386309 |
| RBM25 | RNA binding motif protein 25 | -0.0381562 |
| RPL26 | ribosomal protein L26 | -0.0378889 |
| CDC73 | cell division cycle 73 | -0.03781 |
| SRPK2 | SRSF protein kinase 2 | -0.0377981 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0372748 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0371472 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0371356 |
| GOLGA4 | golgin A4 | -0.0368909 |
| CKAP5 | cytoskeleton associated protein 5 | -0.035813 |
| IPO7 | importin 7 | -0.0357814 |
| TUT4 | terminal uridylyl transferase 4 | -0.0354275 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0348462 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0345368 |
| ZNF326 | zinc finger protein 326 | -0.0341458 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0338353 |
| YBX1 | Y box binding protein 1 | -0.033718 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.033634 |
| MGP | matrix Gla protein | -0.0335349 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0328338 |
| RPL5 | ribosomal protein L5 | -0.0327537 |
| RPL12 | ribosomal protein L12 | -0.0327526 |
| CBX3 | chromobox homolog 3 | -0.0326872 |
| KIF11 | kinesin family member 11 | -0.0324022 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0324009 |
| CECR2 | cat eye syndrome chromosome region, candidate 2 | -0.0317599 |
| SEM1 | SEM1 26S proteasome subunit | -0.0317265 |
| ZNF827 | zinc finger protein 827 | -0.0314433 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0314199 |
| MAP4 | microtubule-associated protein 4 | -0.0313714 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | -0.0310986 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0310274 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0310173 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.030774 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0304416 |
| SAMD8 | sterile alpha motif domain containing 8 | -0.0300608 |
| RREB1 | ras responsive element binding protein 1 | -0.0299774 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0298548 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0296658 |
| TRAF3 | TNF receptor-associated factor 3 | -0.0291937 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0288407 |
| HMGB1 | high mobility group box 1 | -0.0287392 |
| TULP4 | tubby like protein 4 | -0.0286988 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0286918 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0285913 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0284638 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0284582 |
| VPS26A | vacuolar protein sorting 26 homolog A (S. pombe) | -0.0284309 |
| PEG10 | paternally expressed 10 | -0.0283255 |
| TMF1 | TATA element modulatory factor 1 | -0.0277514 |
| ENAH | enabled homolog (Drosophila) | -0.0276629 |
| UBXN4 | UBX domain protein 4 | -0.0276591 |
| RPL11 | ribosomal protein L11 | -0.0276446 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0271465 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0271111 |
| CREBRF | CREB3 regulatory factor | -0.0270405 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0268255 |
| ARL13B | ADP-ribosylation factor-like 13B | -0.0267024 |
| ATRN | attractin | -0.0266143 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | -0.0265912 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0264785 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0262842 |
| SET | SET nuclear proto-oncogene | -0.0262784 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0260956 |
| USP3 | ubiquitin specific peptidase 3 | -0.0260854 |
| ACTN4 | actinin, alpha 4 | -0.0259165 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.025843 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0254954 |
| DEK | DEK proto-oncogene | -0.0253431 |
| RPS2 | ribosomal protein S2 | -0.0253428 |
