| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Folic acid perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Folic acid_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.148514 |
| POTEF | POTE ankyrin domain family, member F | 0.106324 |
| NDRG1 | N-myc downstream regulated 1 | 0.10114 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0982098 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0908896 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0684645 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0632456 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0573593 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0565694 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0555174 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.052623 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0506902 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0506558 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0506544 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0462403 |
| SGMS2 | sphingomyelin synthase 2 | 0.0449431 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0449238 |
| BCL2L1 | BCL2-like 1 | 0.0430424 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.042942 |
| TGM2 | transglutaminase 2 | 0.0425274 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0402183 |
| PCBP2 | poly(rC) binding protein 2 | 0.0390608 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0389701 |
| EFNA5 | ephrin-A5 | 0.0383782 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0371232 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0368899 |
| SERTAD2 | SERTA domain containing 2 | 0.0358049 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0356937 |
| RCOR1 | REST corepressor 1 | 0.0346725 |
| KIAA0040 | KIAA0040 | 0.0341992 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0341934 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0328952 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0326551 |
| ERBIN | erbb2 interacting protein | 0.0314321 |
| VCL | vinculin | 0.031405 |
| TMEM164 | transmembrane protein 164 | 0.0314007 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0310415 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0303251 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0302819 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0301554 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0295488 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0294048 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0291813 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0279038 |
| MMP1 | matrix metallopeptidase 1 | 0.0278803 |
| TSC22D2 | TSC22 domain family, member 2 | 0.027822 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0272185 |
| BMP6 | bone morphogenetic protein 6 | 0.0271863 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0271296 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0267555 |
| ABLIM1 | actin binding LIM protein 1 | 0.0265329 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0263608 |
| ANXA11 | annexin A11 | 0.0262987 |
| GDA | guanine deaminase | 0.025362 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0250675 |
| OXSR1 | oxidative stress responsive 1 | 0.0247023 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.02433 |
| CORO1C | coronin, actin binding protein, 1C | 0.0242443 |
| ANO6 | anoctamin 6 | 0.0242107 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0241773 |
| CD44 | CD44 molecule (Indian blood group) | 0.02405 |
| FER | fer (fps/fes related) tyrosine kinase | 0.024045 |
| IL6ST | interleukin 6 signal transducer | 0.0236961 |
| MSN | moesin | 0.0236851 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0236649 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0234641 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0229704 |
| RUNX1 | runt-related transcription factor 1 | 0.0226611 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0226566 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0225826 |
| WWC1 | WW and C2 domain containing 1 | 0.0225481 |
| CAB39 | calcium binding protein 39 | 0.0222801 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0216298 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0214868 |
| DST | dystonin | 0.0213884 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0213015 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0211736 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.021155 |
| ZFP36 | ZFP36 ring finger protein | 0.0210269 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0209 |
| SMAD3 | SMAD family member 3 | 0.020465 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0203973 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0203617 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0202425 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0201918 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0197857 |
| ITGA6 | integrin, alpha 6 | 0.0197146 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0197026 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0193001 |
| SKIL | SKI-like proto-oncogene | 0.0192654 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0190866 |
| AHR | aryl hydrocarbon receptor | 0.0190086 |
| SVIL | supervillin | 0.0188975 |
| MYADM | myeloid-associated differentiation marker | 0.0187034 |
| SACK1B | scaffolding CK1 anchoring protein B | 0.0186608 |
| DGKH | diacylglycerol kinase, eta | 0.0185265 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0183271 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0182797 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0180883 |
| GTPBP1 | GTP binding protein 1 | 0.0179639 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.186905 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.172749 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.162929 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.161 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.160625 |
| LAMB3 | laminin, beta 3 | -0.147549 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.116759 |
| PTMA | prothymosin, alpha | -0.107233 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.104396 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0992345 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0938186 |
| VIM | vimentin | -0.0867656 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0843468 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0818004 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0747117 |
| PGK1 | phosphoglycerate kinase 1 | -0.0694805 |
| S100A10 | S100 calcium binding protein A10 | -0.0659694 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0653431 |
| RPL37A | ribosomal protein L37a | -0.0618759 |
| ASPH | aspartate beta-hydroxylase | -0.0534393 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0531165 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0526689 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0526022 |
| FTL | ferritin, light polypeptide | -0.0513433 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0508681 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0491266 |
| RBM39 | RNA binding motif protein 39 | -0.0489355 |
| RPL23 | ribosomal protein L23 | -0.0488343 |
| KLK10 | kallikrein-related peptidase 10 | -0.0487324 |
| CANX | calnexin | -0.0486895 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0483212 |
| RPS8 | ribosomal protein S8 | -0.0481006 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.047693 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0473545 |
| RPL12 | ribosomal protein L12 | -0.0470906 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0468947 |
| HMGA1 | high mobility group AT-hook 1 | -0.0464125 |
| SDC4 | syndecan 4 | -0.0460715 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0450428 |
| RPS13 | ribosomal protein S13 | -0.0447825 |
| RPL35A | ribosomal protein L35a | -0.04402 |
| RPL34 | ribosomal protein L34 | -0.0439287 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0431484 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0429424 |
| ANXA2 | annexin A2 | -0.0425198 |
| SQSTM1 | sequestosome 1 | -0.0424614 |
| GOLGA4 | golgin A4 | -0.042101 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0419648 |
| B2M | beta-2-microglobulin | -0.041406 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0407287 |
| ACTG1 | actin gamma 1 | -0.0406712 |
| RPS27A | ribosomal protein S27a | -0.0405952 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0403715 |
| RPL26 | ribosomal protein L26 | -0.04021 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0401964 |
| LDHA | lactate dehydrogenase A | -0.0401542 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0394847 |
| RPLP1 | ribosomal protein, large, P1 | -0.0392036 |
| MTDH | metadherin | -0.0388014 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0382294 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.037758 |
| RPS24 | ribosomal protein S24 | -0.037527 |
| LMO7 | LIM domain 7 | -0.0374581 |
| CD2AP | CD2-associated protein | -0.0373789 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0371401 |
| SP100 | SP100 nuclear antigen | -0.0370543 |
| PERP | PERP, TP53 apoptosis effector | -0.0368026 |
| RPL36A | ribosomal protein L36a | -0.0367045 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0365176 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.036276 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0360664 |
| COG5 | component of oligomeric golgi complex 5 | -0.0356805 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0355555 |
| RPS3 | ribosomal protein S3 | -0.0347761 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0347337 |
| RPL11 | ribosomal protein L11 | -0.0343324 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0343023 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0342946 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0342845 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0341621 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0339937 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0338247 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0335111 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0334457 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.033419 |
| RPS21 | ribosomal protein S21 | -0.0331104 |
| TMSB4X | thymosin beta 4, X-linked | -0.0330792 |
| RPL37 | ribosomal protein L37 | -0.0329307 |
| RPL31 | ribosomal protein L31 | -0.0329249 |
| PARD3 | par-3 family cell polarity regulator | -0.032404 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0324039 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0322763 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0322634 |
| RBM25 | RNA binding motif protein 25 | -0.0320737 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.032018 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0317268 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0315922 |
| S100A6 | S100 calcium binding protein A6 | -0.0301038 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0298929 |
| RPS25 | ribosomal protein S25 | -0.0298579 |
