| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Folic acid perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Folic acid_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.329226 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.164945 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.150789 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.150572 |
| GPC6 | glypican 6 | 0.125103 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.11752 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.114049 |
| ENO1 | enolase 1, (alpha) | 0.0920882 |
| ASPH | aspartate beta-hydroxylase | 0.0737784 |
| FRMD4A | FERM domain containing 4A | 0.0712786 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0564385 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0503624 |
| NLGN1 | neuroligin 1 | 0.0488147 |
| SETBP1 | SET binding protein 1 | 0.0481619 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0477742 |
| PCDH7 | protocadherin 7 | 0.0474323 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0463281 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0447855 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0433151 |
| VIM | vimentin | 0.0421716 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.039839 |
| PKM | pyruvate kinase, muscle | 0.0392718 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0391541 |
| PARVB | parvin, beta | 0.0383722 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0371711 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0370651 |
| DST | dystonin | 0.0360639 |
| TNNC1 | troponin C type 1 (slow) | 0.0349117 |
| EXOC4 | exocyst complex component 4 | 0.0348083 |
| ACTN1 | actinin, alpha 1 | 0.033642 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0334781 |
| ARFGEF3 | ARFGEF family member 3 | 0.0333245 |
| PRELID2 | PRELI domain containing 2 | 0.0327753 |
| PYGL | phosphorylase, glycogen, liver | 0.0321431 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | 0.0316578 |
| A2M | alpha-2-macroglobulin | 0.0315119 |
| OXR1 | oxidation resistance 1 | 0.0308067 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0302522 |
| RAD51B | RAD51 paralog B | 0.0290447 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0289909 |
| LDHA | lactate dehydrogenase A | 0.0276277 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0275748 |
| ITGB8 | integrin, beta 8 | 0.0275628 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0273949 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.027165 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.025715 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.025645 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0255796 |
| COL19A1 | collagen, type XIX, alpha 1 | 0.0252019 |
| SHROOM4 | shroom family member 4 | 0.0249195 |
| NRP2 | neuropilin 2 | 0.0245129 |
| ZNF704 | zinc finger protein 704 | 0.024126 |
| MTERF1 | mitochondrial transcription termination factor 1 | 0.0239532 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | 0.0239492 |
| VMP1 | vacuole membrane protein 1 | 0.0239207 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0238885 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0238862 |
| TPM4 | tropomyosin 4 | 0.0234899 |
| ACTG1 | actin gamma 1 | 0.0233405 |
| AHNAK | AHNAK nucleoprotein | 0.0232668 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0228279 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0224496 |
| PUS7 | pseudouridylate synthase 7 (putative) | 0.022332 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0220239 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0214074 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0213652 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0211724 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.021069 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0210304 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0208603 |
| OSMR | oncostatin M receptor | 0.0203631 |
| SMYD3 | SET and MYND domain containing 3 | 0.0203397 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0201319 |
| IL6ST | interleukin 6 signal transducer | 0.020022 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.020015 |
| ZYX | zyxin | 0.0198387 |
| BPTF | bromodomain PHD finger transcription factor | 0.019415 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0192189 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0189122 |
| SEPTIN9 | septin 9 | 0.0188426 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0187777 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0185981 |
| AHR | aryl hydrocarbon receptor | 0.0184979 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0183905 |
| RCAN1 | regulator of calcineurin 1 | 0.0183688 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.018322 |
| RHOJ | ras homolog family member J | 0.0182479 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0182341 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0181628 |
| AFAP1 | actin filament associated protein 1 | 0.0178391 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0175219 |
| CTTNBP2 | cortactin binding protein 2 | 0.0173673 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0173349 |
| SFTPA2 | surfactant protein A2 | 0.0173252 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0172609 |
| JMJD1C | jumonji domain containing 1C | 0.0172342 |
| TMEM255B | transmembrane protein 255B | 0.0171482 |
| CANX | calnexin | 0.0170907 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0170276 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0168219 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0932381 |
| NDRG1 | N-myc downstream regulated 1 | -0.0831003 |
| VGF | VGF nerve growth factor inducible | -0.0717008 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0715293 |
| NBAS | neuroblastoma amplified sequence | -0.0679224 |
| PTK2 | protein tyrosine kinase 2 | -0.0672088 |
| CDC73 | cell division cycle 73 | -0.0644481 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0641145 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0625389 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0619695 |
| RNF145 | ring finger protein 145 | -0.0585266 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0566847 |
| FMNL2 | formin-like 2 | -0.0554072 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0515863 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0509611 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0490259 |
| COPA | coatomer protein complex, subunit alpha | -0.04729 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0471539 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0468283 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.046709 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.045475 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.043817 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0427359 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0413673 |
| NUP58 | nucleoporin 58 | -0.0410003 |
| MT2A | metallothionein 2A | -0.0396265 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.039289 |
| NPR2 | natriuretic peptide receptor 2 | -0.0392819 |
| TMSB10 | thymosin beta 10 | -0.0378419 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.037772 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0375297 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0362153 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0356451 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0356385 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0353524 |
| TNPO3 | transportin 3 | -0.0338117 |
| MEF2A | myocyte enhancer factor 2A | -0.0333362 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0329752 |
| WDR45B | WD repeat domain 45B | -0.0328277 |
| GDF15 | growth differentiation factor 15 | -0.0328275 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0326593 |
| TPD52 | tumor protein D52 | -0.0323309 |
| DENND1A | DENN/MADD domain containing 1A | -0.0322833 |
| HELZ | helicase with zinc finger | -0.0320846 |
| HLA-B | major histocompatibility complex, class I, B | -0.0319787 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0312636 |
| PRKD1 | protein kinase D1 | -0.0305522 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.030392 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0301358 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0296587 |
| SBF2 | SET binding factor 2 | -0.0288632 |
| CD109 | CD109 molecule | -0.0288343 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0287041 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0283763 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0281633 |
| RBM33 | RNA binding motif protein 33 | -0.0280485 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0276251 |
| CENPF | centromere protein F, 350/400kDa | -0.0274432 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0270713 |
| RBM39 | RNA binding motif protein 39 | -0.0266975 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0265146 |
| SETD5 | SET domain containing 5 | -0.0264877 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0264806 |
| PTCHD4 | patched domain containing 4 | -0.0264274 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0263083 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0262742 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0262508 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0261038 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0259413 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0259159 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0258664 |
| RCOR1 | REST corepressor 1 | -0.0255406 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0251204 |
| FBXO42 | F-box protein 42 | -0.0250391 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0249774 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0249159 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0247874 |
| HMCN1 | hemicentin 1 | -0.0247448 |
| TAGLN2 | transgelin 2 | -0.0246602 |
| RBM25 | RNA binding motif protein 25 | -0.024622 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0244889 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0244539 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0242729 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0241843 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0241456 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0239727 |
| MT1X | metallothionein 1X | -0.0238456 |
| CERT1 | ceramide transporter 1 | -0.0234385 |
| ATP11B | ATPase, class VI, type 11B | -0.0231402 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.023053 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0228656 |
| ATP13A3 | ATPase type 13A3 | -0.0228162 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.0225832 |
| CABIN1 | calcineurin binding protein 1 | -0.0224312 |
| COG5 | component of oligomeric golgi complex 5 | -0.0223034 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0221443 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0219165 |
| CUL3 | cullin 3 | -0.0219029 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0214171 |
| SNX13 | sorting nexin 13 | -0.0214132 |
