| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Folic acid perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Folic acid_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.169868 |
| MEIS2 | Meis homeobox 2 | 0.129742 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0748119 |
| IGF2 | insulin-like growth factor 2 | 0.0738528 |
| DPH6 | diphthamine biosynthesis 6 | 0.0736297 |
| MAP1B | microtubule-associated protein 1B | 0.0699877 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0657083 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0644236 |
| MYO6 | myosin VI | 0.0565008 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0551888 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0547809 |
| FHIT | fragile histidine triad | 0.0525704 |
| AOPEP | aminopeptidase O (putative) | 0.0520784 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0500897 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0493793 |
| PTEN | phosphatase and tensin homolog | 0.0464729 |
| FMN1 | formin 1 | 0.0464112 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0458123 |
| AUTS2 | autism susceptibility candidate 2 | 0.0456243 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0452689 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0449329 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0448884 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0446308 |
| PLPP1 | phospholipid phosphatase 1 | 0.043994 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0433199 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0426591 |
| NRP1 | neuropilin 1 | 0.0425149 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0414652 |
| KLHL13 | kelch-like family member 13 | 0.0400567 |
| DNM3 | dynamin 3 | 0.0398592 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0392306 |
| ANGPT1 | angiopoietin 1 | 0.0388308 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0381585 |
| NRG1 | neuregulin 1 | 0.037652 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0361185 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0356432 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.035305 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0352697 |
| SYT1 | synaptotagmin I | 0.0351191 |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 | 0.0347255 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.033877 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0331451 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | 0.0329006 |
| APP | amyloid beta (A4) precursor protein | 0.0325609 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0319344 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0316294 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.0315468 |
| ATXN1 | ataxin 1 | 0.0314683 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0314358 |
| SKIL | SKI-like proto-oncogene | 0.0314141 |
| TCF12 | transcription factor 12 | 0.0313667 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0312623 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0312254 |
| PRRC2B | proline-rich coiled-coil 2B | 0.030887 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0308131 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0304635 |
| ANO6 | anoctamin 6 | 0.0302374 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0300062 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0297254 |
| DNMBP | dynamin binding protein | 0.029642 |
| EXOC4 | exocyst complex component 4 | 0.0291929 |
| TBX2 | T-box 2 | 0.029178 |
| SRPK2 | SRSF protein kinase 2 | 0.0289797 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0289123 |
| CARD16 | caspase recruitment domain family, member 16 | 0.02885 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0286129 |
| USP34 | ubiquitin specific peptidase 34 | 0.0285898 |
| FOXP1 | forkhead box P1 | 0.0283322 |
| PTK2 | protein tyrosine kinase 2 | 0.0281481 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0276784 |
| RO60 | Ro60, Y RNA binding protein | 0.0275445 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | 0.0274253 |
| DUSP10 | dual specificity phosphatase 10 | 0.0273722 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0270632 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) | 0.0268976 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0268186 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0267623 |
| RFX7 | regulatory factor X, 7 | 0.0267144 |
| GNAS | GNAS complex locus | 0.0264865 |
| TBC1D4 | TBC1 domain family, member 4 | 0.026444 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0263779 |
| ZNF292 | zinc finger protein 292 | 0.0260138 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0259073 |
| MEF2A | myocyte enhancer factor 2A | 0.0256815 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0252906 |
| GATA3 | GATA binding protein 3 | 0.0251583 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0248254 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0247566 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0246309 |
| ZFHX3 | zinc finger homeobox 3 | 0.0245029 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.024381 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0243251 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0240227 |
| TPR | translocated promoter region, nuclear basket protein | 0.0239622 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0238713 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.02381 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0237744 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.0235558 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0235528 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0235379 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | -0.153053 |
| EXT1 | exostosin glycosyltransferase 1 | -0.120328 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0931342 |
| TRIB2 | tribbles pseudokinase 2 | -0.0901996 |
| LSAMP | limbic system-associated membrane protein | -0.0791598 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0651657 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.064105 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.058656 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0543822 |
| MCL1 | myeloid cell leukemia 1 | -0.0506193 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0501126 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0469888 |
| TPM1 | tropomyosin 1 (alpha) | -0.0465872 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0456964 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0448419 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0430493 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0430417 |
| AEBP2 | AE binding protein 2 | -0.0415813 |
| MYO1E | myosin IE | -0.0407046 |
| EGFR | epidermal growth factor receptor | -0.0405083 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0398807 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0395894 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0395832 |
| GSE1 | Gse1 coiled-coil protein | -0.0380382 |
| ACTG1 | actin gamma 1 | -0.0377878 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0369925 |
| ACTN1 | actinin, alpha 1 | -0.0364704 |
| ARF1 | ADP-ribosylation factor 1 | -0.0363743 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0355825 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0338908 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0338628 |
| COL1A1 | collagen, type I, alpha 1 | -0.0338471 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.032908 |
| CUX1 | cut-like homeobox 1 | -0.0324349 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0324009 |
| SEPTIN9 | septin 9 | -0.032232 |
| CORIN | corin, serine peptidase | -0.0320441 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.031965 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0318441 |
| MORF4L2 | mortality factor 4 like 2 | -0.0315669 |
| CANX | calnexin | -0.0312729 |
| EGR1 | early growth response 1 | -0.0310232 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0305276 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0297258 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0294312 |
| CCDC47 | coiled-coil domain containing 47 | -0.0292857 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.029262 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0290178 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0286905 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0285199 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0283796 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0279774 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0279451 |
| INTS6 | integrator complex subunit 6 | -0.0276335 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0275366 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0273455 |
| FRMD4A | FERM domain containing 4A | -0.0271176 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0268194 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0266965 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0264043 |
| RNF150 | ring finger protein 150 | -0.0262543 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0260503 |
| NREP | neuronal regeneration related protein | -0.0257411 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0257209 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0256748 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0256558 |
| COL3A1 | collagen, type III, alpha 1 | -0.0254418 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0252779 |
| RRBP1 | ribosome binding protein 1 | -0.0251838 |
| GOLGB1 | golgin B1 | -0.0251234 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.024911 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0246111 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0245451 |
| VGF | VGF nerve growth factor inducible | -0.0244279 |
| SMAD3 | SMAD family member 3 | -0.0243107 |
| IER3 | immediate early response 3 | -0.0242925 |
| CLINT1 | clathrin interactor 1 | -0.0241447 |
| CTBP2 | C-terminal binding protein 2 | -0.023892 |
| ANK2 | ankyrin 2, neuronal | -0.0238061 |
| DACH2 | dachshund family transcription factor 2 | -0.0236371 |
| PCDH11Y | protocadherin 11 Y-linked | -0.0234186 |
| LMO7 | LIM domain 7 | -0.0233673 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0232556 |
| RPL23 | ribosomal protein L23 | -0.0231554 |
| DIAPH2 | diaphanous-related formin 2 | -0.0231257 |
| CDH13 | cadherin 13 | -0.0231097 |
| KIAA1217 | KIAA1217 | -0.0230894 |
| DTNA | dystrobrevin, alpha | -0.0230245 |
| SCFD1 | sec1 family domain containing 1 | -0.0229858 |
| EFNA5 | ephrin-A5 | -0.02297 |
| JAK1 | Janus kinase 1 | -0.0228964 |
| FAM107B | family with sequence similarity 107, member B | -0.0228661 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0228057 |
| PSEN1 | presenilin 1 | -0.0228046 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0227137 |
| THOC2 | THO complex 2 | -0.0225779 |
| ACTN4 | actinin, alpha 4 | -0.02257 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0225457 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0224887 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0224849 |
