| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Folic acid perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Folic acid_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GMDS | GDP-mannose 4,6-dehydratase | 0.120971 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.106447 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.103298 |
| LMO7 | LIM domain 7 | 0.0984086 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0906802 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0884533 |
| ITGA6 | integrin, alpha 6 | 0.0854708 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0769686 |
| LCN2 | lipocalin 2 | 0.0763527 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0712314 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0711482 |
| ERBIN | erbb2 interacting protein | 0.0700192 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0684633 |
| LYZ | lysozyme | 0.0660308 |
| MSI2 | musashi RNA-binding protein 2 | 0.0637974 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0637283 |
| PRKCA | protein kinase C, alpha | 0.0596131 |
| SPATA13 | spermatogenesis associated 13 | 0.0591834 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0580661 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0549937 |
| TMC5 | transmembrane channel-like 5 | 0.0547805 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0543192 |
| ATP10B | ATPase, class V, type 10B | 0.0516047 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0510651 |
| NPSR1 | neuropeptide S receptor 1 | 0.0498153 |
| ETV6 | ets variant 6 | 0.0493993 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0492187 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0486352 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0450347 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0444786 |
| PTMA | prothymosin, alpha | 0.0443639 |
| SQSTM1 | sequestosome 1 | 0.0438561 |
| JUN | jun proto-oncogene | 0.0423063 |
| AREG | amphiregulin | 0.0415989 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0414458 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.0412004 |
| TRIM2 | tripartite motif containing 2 | 0.0401691 |
| SSH2 | slingshot protein phosphatase 2 | 0.039892 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0395798 |
| MYO1E | myosin IE | 0.0392132 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0391562 |
| EPHB2 | EPH receptor B2 | 0.0387182 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0377156 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0372854 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0371153 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0371042 |
| MUC13 | mucin 13, cell surface associated | 0.0347429 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0345578 |
| MX1 | MX dynamin-like GTPase 1 | 0.0341712 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0337678 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.033767 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0337045 |
| PTGR1 | prostaglandin reductase 1 | 0.0324356 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0316353 |
| HLA-B | major histocompatibility complex, class I, B | 0.0315705 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0314578 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0312334 |
| BCL2L1 | BCL2-like 1 | 0.0311632 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0310627 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0309614 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0305106 |
| XAF1 | XIAP associated factor 1 | 0.0301736 |
| EZR | ezrin | 0.030011 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0297877 |
| TMSB10 | thymosin beta 10 | 0.0297456 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0295009 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0294889 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0291266 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.028664 |
| RBM47 | RNA binding motif protein 47 | 0.0282028 |
| EGR1 | early growth response 1 | 0.02795 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | 0.0277399 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 0.0273338 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0273198 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0272948 |
| ATP11A | ATPase, class VI, type 11A | 0.0270573 |
| ZNRF3 | zinc and ring finger 3 | 0.0269016 |
| KYNU | kynureninase | 0.0268362 |
| FHIT | fragile histidine triad | 0.0262489 |
| ANXA2 | annexin A2 | 0.0262017 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0260438 |
| FTL | ferritin, light polypeptide | 0.0257003 |
| SMAD3 | SMAD family member 3 | 0.0253198 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0251997 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0245469 |
| NPAS2 | neuronal PAS domain protein 2 | 0.024365 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0242898 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0236449 |
| USP54 | ubiquitin specific peptidase 54 | 0.0234944 |
| MX2 | MX dynamin-like GTPase 2 | 0.0234931 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0231984 |
| POTEF | POTE ankyrin domain family, member F | 0.023152 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0229769 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0228984 |
| RASAL2 | RAS protein activator like 2 | 0.0227694 |
| DIAPH1 | diaphanous-related formin 1 | 0.0226999 |
| MCL1 | myeloid cell leukemia 1 | 0.0225496 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0224812 |
| JMJD1C | jumonji domain containing 1C | 0.0223145 |
| B2M | beta-2-microglobulin | 0.0222542 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.198913 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0966245 |
| DSCAM | Down syndrome cell adhesion molecule | -0.069369 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.069105 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0684572 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0666239 |
| PHF3 | PHD finger protein 3 | -0.0635416 |
| TXNIP | thioredoxin interacting protein | -0.0599583 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0538004 |
| INTS6 | integrator complex subunit 6 | -0.0530343 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0523522 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0510799 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0492997 |
| GOLGB1 | golgin B1 | -0.0490415 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0478023 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0458193 |
| AHI1 | Abelson helper integration site 1 | -0.0456295 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0444059 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.043556 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0434736 |
| IFNGR1 | interferon gamma receptor 1 | -0.0424148 |
| CANX | calnexin | -0.0420958 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0415568 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.041236 |
| SBF2 | SET binding factor 2 | -0.0396926 |
| HDLBP | high density lipoprotein binding protein | -0.0388584 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0379443 |
| SUCO | SUN domain containing ossification factor | -0.0375943 |
| SEC24D | SEC24 family member D | -0.0369249 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0367702 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0342978 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0341837 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0332373 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.0329893 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0315528 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0313811 |
| RBM39 | RNA binding motif protein 39 | -0.0302272 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.029887 |
| PLSCR2 | phospholipid scramblase 2 | -0.0298782 |
| NCKAP5 | NCK-associated protein 5 | -0.0296967 |
| COG6 | component of oligomeric golgi complex 6 | -0.0292736 |
| USP3 | ubiquitin specific peptidase 3 | -0.0291871 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.028332 |
| GOLGA4 | golgin A4 | -0.0277957 |
| RNF43 | ring finger protein 43 | -0.0277721 |
| FNIP1 | folliculin interacting protein 1 | -0.0275812 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0273586 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0263633 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0261672 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0259321 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0252726 |
| MAP7 | microtubule-associated protein 7 | -0.0252341 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.025043 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0247998 |
| SSR1 | signal sequence receptor, alpha | -0.024764 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0245707 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | -0.0241899 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.024068 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0239804 |
| HELZ | helicase with zinc finger | -0.0236963 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0236207 |
| ARGLU1 | arginine and glutamate rich 1 | -0.0235042 |
| TBPL1 | TBP-like 1 | -0.0234345 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.023139 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0231127 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0229355 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0226325 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.022499 |
| EPCAM | epithelial cell adhesion molecule | -0.0223853 |
| EHF | ets homologous factor | -0.0223702 |
| MATR3 | matrin 3 | -0.0223423 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | -0.0222719 |
| LMAN1 | lectin, mannose-binding, 1 | -0.022016 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0218609 |
| TSC22D2 | TSC22 domain family, member 2 | -0.021694 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0216746 |
| HBS1L | HBS1-like translational GTPase | -0.0215879 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | -0.0215638 |
| TMEM39A | transmembrane protein 39A | -0.0215103 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0214296 |
| RRBP1 | ribosome binding protein 1 | -0.0211035 |
| PRELID2 | PRELI domain containing 2 | -0.0210338 |
| CLTC | clathrin, heavy chain (Hc) | -0.0209972 |
| STK24 | serine/threonine kinase 24 | -0.0208419 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0207786 |
| RBM26 | RNA binding motif protein 26 | -0.0206585 |
| OGA | O-GlcNAcase | -0.0206347 |
| CALR | calreticulin | -0.0205763 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0203953 |
| ZNF451 | zinc finger protein 451 | -0.0202689 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0202457 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.01985 |
| CEP350 | centrosomal protein 350kDa | -0.0197555 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | -0.0196525 |
| MED13L | mediator complex subunit 13-like | -0.0196041 |
| ERP44 | endoplasmic reticulum protein 44 | -0.0194967 |
| NUCB2 | nucleobindin 2 | -0.0193927 |
| DIAPH3 | diaphanous-related formin 3 | -0.0193026 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0192376 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.019211 |