| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Folic acid perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Folic acid_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.185199 |
| NLGN1 | neuroligin 1 | 0.0955785 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0780912 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0704281 |
| MKI67 | marker of proliferation Ki-67 | 0.0634896 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0573616 |
| TXNRD1 | thioredoxin reductase 1 | 0.0551432 |
| SMAD3 | SMAD family member 3 | 0.0545806 |
| PKM | pyruvate kinase, muscle | 0.0531117 |
| RUNX1 | runt-related transcription factor 1 | 0.0472388 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.047004 |
| MSN | moesin | 0.0454149 |
| FAM13A | family with sequence similarity 13, member A | 0.0431536 |
| PTK2 | protein tyrosine kinase 2 | 0.0403589 |
| ANLN | anillin, actin binding protein | 0.0394001 |
| NAV2 | neuron navigator 2 | 0.0391264 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0389832 |
| MAP1B | microtubule-associated protein 1B | 0.0388516 |
| ZNF638 | zinc finger protein 638 | 0.0376673 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0365042 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0361009 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0350144 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0342333 |
| ANXA2 | annexin A2 | 0.0336758 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0325012 |
| CKAP5 | cytoskeleton associated protein 5 | 0.03218 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0321025 |
| FOXJ3 | forkhead box J3 | 0.0309745 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0309568 |
| FAM219A | family with sequence similarity 219, member A | 0.0306524 |
| ATXN1 | ataxin 1 | 0.0305282 |
| DNMBP | dynamin binding protein | 0.0302288 |
| CEP112 | centrosomal protein 112kDa | 0.0300039 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0297043 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | 0.0293363 |
| NDRG1 | N-myc downstream regulated 1 | 0.0287094 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0286464 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0286004 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0285993 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0283713 |
| RNF220 | ring finger protein 220 | 0.028205 |
| PDE8A | phosphodiesterase 8A | 0.0280005 |
| USP47 | ubiquitin specific peptidase 47 | 0.0279852 |
| KIF4A | kinesin family member 4A | 0.0279594 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0276227 |
| USP24 | ubiquitin specific peptidase 24 | 0.0273559 |
| SMYD3 | SET and MYND domain containing 3 | 0.02731 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0266684 |
| YEATS2 | YEATS domain containing 2 | 0.0265305 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0265231 |
| RNF216 | ring finger protein 216 | 0.0262336 |
| XPO1 | exportin 1 | 0.0256571 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0254911 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0252934 |
| METTL15 | methyltransferase like 15 | 0.0250684 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0244134 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0243708 |
| GLIS3 | GLIS family zinc finger 3 | 0.0238059 |
| H1-2 | H1.2 linker histone, cluster member | 0.0237784 |
| FAM20C | family with sequence similarity 20, member C | 0.0235198 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0233691 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0233562 |
| FTO | fat mass and obesity associated | 0.0233462 |
| ETV6 | ets variant 6 | 0.0231672 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.023086 |
| DST | dystonin | 0.0228756 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0228623 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0228426 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0228372 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0228033 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0227276 |
| RBM39 | RNA binding motif protein 39 | 0.0226033 |
| CENPF | centromere protein F, 350/400kDa | 0.0225374 |
| JMJD1C | jumonji domain containing 1C | 0.0223993 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0223804 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0222335 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0222058 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0221124 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0220074 |
| KYNU | kynureninase | 0.0219297 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.021913 |
| SNX13 | sorting nexin 13 | 0.0218204 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0216253 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0215796 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0215732 |
| RNF213 | ring finger protein 213 | 0.021507 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0213807 |
| HJURP | Holliday junction recognition protein | 0.0212686 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0212159 |
| CALN1 | calneuron 1 | 0.0212138 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0212054 |
| HELZ | helicase with zinc finger | 0.0211711 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0211584 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0210952 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0210138 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0210083 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0209381 |
| PCBP3 | poly(rC) binding protein 3 | 0.0209024 |
| PHF21A | PHD finger protein 21A | 0.020845 |
| RNF145 | ring finger protein 145 | 0.020711 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.160356 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.14311 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.128348 |
| MT2A | metallothionein 2A | -0.125824 |
| TMSB10 | thymosin beta 10 | -0.117727 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.102689 |
| B2M | beta-2-microglobulin | -0.0951056 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0948386 |
| HLA-B | major histocompatibility complex, class I, B | -0.0799943 |
| FN1 | fibronectin 1 | -0.0787589 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0786923 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0774999 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0768543 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0750462 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0614962 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0607097 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0606668 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0603935 |
| INHBA | inhibin, beta A | -0.0564574 |
| CALD1 | caldesmon 1 | -0.0530064 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0504017 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0503782 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0501059 |
| LOX | lysyl oxidase | -0.0499033 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.049683 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0459685 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0455932 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0455927 |
| PRSS23 | protease, serine, 23 | -0.0452473 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0446001 |
| FTL | ferritin, light polypeptide | -0.0444428 |
| CLMP | CXADR-like membrane protein | -0.0437317 |
| DTNA | dystrobrevin, alpha | -0.0436203 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0424316 |
| RPS24 | ribosomal protein S24 | -0.0421114 |
| RPL34 | ribosomal protein L34 | -0.0404373 |
| HDAC9 | histone deacetylase 9 | -0.0402264 |
| RPS8 | ribosomal protein S8 | -0.0399872 |
| GNAS | GNAS complex locus | -0.0394945 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0390589 |
| RPS19 | ribosomal protein S19 | -0.0384903 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0371893 |
| SDC4 | syndecan 4 | -0.0370723 |
| IGF2 | insulin-like growth factor 2 | -0.0364377 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0364353 |
| RPL35A | ribosomal protein L35a | -0.036215 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0361948 |
| RPS3 | ribosomal protein S3 | -0.0360864 |
| S100A6 | S100 calcium binding protein A6 | -0.0356278 |
| RIGI | RNA sensor RIG-I | -0.0352424 |
| RPS6 | ribosomal protein S6 | -0.0351678 |
| CCND1 | cyclin D1 | -0.0344708 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0335877 |
| EGR1 | early growth response 1 | -0.0326776 |
| HLA-A | major histocompatibility complex, class I, A | -0.0323222 |
| HLA-C | major histocompatibility complex, class I, C | -0.0320313 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0320002 |
| RPL9 | ribosomal protein L9 | -0.0313058 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0312119 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0312065 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0310279 |
| S100A10 | S100 calcium binding protein A10 | -0.0304384 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0303644 |
| RPLP0 | ribosomal protein, large, P0 | -0.0297778 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0296478 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.029285 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0292641 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0289634 |
| RACK1 | receptor for activated C kinase 1 | -0.0287322 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0285857 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.02844 |
| EGFR | epidermal growth factor receptor | -0.028332 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0279294 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0270648 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 | -0.0263663 |
| CCNI | cyclin I | -0.0260883 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -0.0255993 |
| RPL12 | ribosomal protein L12 | -0.0252701 |
| RPL36A | ribosomal protein L36a | -0.0250561 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0250472 |
| INTS6 | integrator complex subunit 6 | -0.0248452 |
| RPL19 | ribosomal protein L19 | -0.0245253 |
| TMSB4X | thymosin beta 4, X-linked | -0.0245124 |
| PTMA | prothymosin, alpha | -0.0244932 |
| ASPH | aspartate beta-hydroxylase | -0.0244603 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0239216 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.023898 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0238566 |
| TPI1 | triosephosphate isomerase 1 | -0.0238134 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0233222 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0231714 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0231587 |
| XYLT1 | xylosyltransferase I | -0.0230775 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0227781 |
| TRIM56 | tripartite motif containing 56 | -0.0226997 |
| RPL23 | ribosomal protein L23 | -0.0226539 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0226001 |
| TMEM132B | transmembrane protein 132B | -0.0225715 |
| HIP1 | huntingtin interacting protein 1 | -0.0225327 |
| MMP12 | matrix metallopeptidase 12 | -0.0224521 |
