| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Folic acid perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Folic acid_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.25893 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.255993 |
| CD44 | CD44 molecule (Indian blood group) | 0.15874 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.146548 |
| DST | dystonin | 0.118444 |
| HMGA2 | high mobility group AT-hook 2 | 0.11451 |
| NDRG1 | N-myc downstream regulated 1 | 0.105526 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.100144 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.096714 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0962359 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0936235 |
| AHNAK | AHNAK nucleoprotein | 0.0906856 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.090634 |
| ASPH | aspartate beta-hydroxylase | 0.0787873 |
| ENO1 | enolase 1, (alpha) | 0.0745496 |
| ANXA2 | annexin A2 | 0.0728764 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0727833 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0701296 |
| VIM | vimentin | 0.0676258 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0665909 |
| IGF2 | insulin-like growth factor 2 | 0.0626732 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0625351 |
| MAP1B | microtubule-associated protein 1B | 0.0622268 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0603585 |
| MYO10 | myosin X | 0.0603161 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0594037 |
| RAI14 | retinoic acid induced 14 | 0.0593086 |
| PKM | pyruvate kinase, muscle | 0.0590728 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0564331 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0546826 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0528542 |
| DNMBP | dynamin binding protein | 0.0515556 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0510239 |
| CLIC4 | chloride intracellular channel 4 | 0.0490576 |
| CDCP1 | CUB domain containing protein 1 | 0.0474523 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0470333 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0470312 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0467323 |
| MSN | moesin | 0.0461283 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0447734 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0435062 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0432709 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.043205 |
| PGK1 | phosphoglycerate kinase 1 | 0.0429329 |
| VCL | vinculin | 0.0427172 |
| SMAD3 | SMAD family member 3 | 0.0423434 |
| MCL1 | myeloid cell leukemia 1 | 0.0418719 |
| PRELID2 | PRELI domain containing 2 | 0.0418371 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0416537 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0410756 |
| FLNB | filamin B, beta | 0.0408442 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0407034 |
| GLIS3 | GLIS family zinc finger 3 | 0.0401534 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0400995 |
| PTK2 | protein tyrosine kinase 2 | 0.0400734 |
| ACTN4 | actinin, alpha 4 | 0.0384409 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0368469 |
| LDHA | lactate dehydrogenase A | 0.0368122 |
| PRKCA | protein kinase C, alpha | 0.0364648 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0361094 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0357916 |
| STC1 | stanniocalcin 1 | 0.0357547 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.035463 |
| TENM2 | teneurin transmembrane protein 2 | 0.0352458 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0351648 |
| TMSB10 | thymosin beta 10 | 0.0349383 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0346818 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0345772 |
| LOX | lysyl oxidase | 0.0342561 |
| COL5A1 | collagen, type V, alpha 1 | 0.0341277 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0339465 |
| SEPTIN9 | septin 9 | 0.033862 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0337045 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0331313 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.032881 |
| TUBB6 | tubulin, beta 6 class V | 0.0326356 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0324252 |
| RRM2 | ribonucleotide reductase M2 | 0.0323686 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0315229 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0306772 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0306671 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0303484 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0296475 |
| VEGFC | vascular endothelial growth factor C | 0.0296264 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0294934 |
| DIAPH2 | diaphanous-related formin 2 | 0.0288777 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0287558 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0285835 |
| RAD51B | RAD51 paralog B | 0.0283004 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0282163 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0281063 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0280193 |
| VMP1 | vacuole membrane protein 1 | 0.0279842 |
| LOXL2 | lysyl oxidase-like 2 | 0.0278593 |
| NUMB | numb homolog (Drosophila) | 0.027062 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0270617 |
| ETV6 | ets variant 6 | 0.0266958 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0265232 |
| TGFB1 | transforming growth factor, beta 1 | 0.0264132 |
| SMYD3 | SET and MYND domain containing 3 | 0.0262713 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | -0.0332058 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0306688 |
| FNIP1 | folliculin interacting protein 1 | -0.0202107 |
| GOLGB1 | golgin B1 | -0.0195428 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0183375 |
| MT2A | metallothionein 2A | -0.0172498 |
| RPS8 | ribosomal protein S8 | -0.0168373 |
| GOLGA4 | golgin A4 | -0.0162605 |
| RPL9 | ribosomal protein L9 | -0.0155778 |
| RPL31 | ribosomal protein L31 | -0.0155395 |
| RPL12 | ribosomal protein L12 | -0.0154998 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0154905 |
| PHF3 | PHD finger protein 3 | -0.0154267 |
| RPL37A | ribosomal protein L37a | -0.0152608 |
| RPL34 | ribosomal protein L34 | -0.01469 |
| RPL23 | ribosomal protein L23 | -0.0141053 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0135912 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0134985 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0134647 |
| RPL35A | ribosomal protein L35a | -0.0133356 |
| NAV2 | neuron navigator 2 | -0.0130778 |
| RPS24 | ribosomal protein S24 | -0.012563 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0124455 |
| MT1E | metallothionein 1E | -0.0118065 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0115669 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0114985 |
| MMP12 | matrix metallopeptidase 12 | -0.0113695 |
| AEBP2 | AE binding protein 2 | -0.0110378 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0110153 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0109924 |
| RPL11 | ribosomal protein L11 | -0.0109677 |
| DENND5B | DENN/MADD domain containing 5B | -0.0109292 |
| SQSTM1 | sequestosome 1 | -0.0106572 |
| NUP98 | nucleoporin 98kDa | -0.0104053 |
| TXLNG | taxilin gamma | -0.010355 |
| IL11 | interleukin 11 | -0.0103051 |
| CCDC138 | coiled-coil domain containing 138 | -0.0100764 |
| RPL37 | ribosomal protein L37 | -0.0098952 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0097934 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.00968925 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.00967635 |
| RPS3 | ribosomal protein S3 | -0.00955302 |
| GRB10 | growth factor receptor-bound protein 10 | -0.00935655 |
| RPL26 | ribosomal protein L26 | -0.00930149 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00929267 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0091799 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.00912666 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.00906937 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.00894458 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.00878515 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.00863172 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.00851486 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | -0.00839222 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.00813435 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0081074 |
| NKTR | natural killer cell triggering receptor | -0.00804911 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.00802247 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.00801905 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.00798718 |
| RBM25 | RNA binding motif protein 25 | -0.00792414 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0079177 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.00790638 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.00787752 |
| AFTPH | aftiphilin | -0.00787439 |
| NABP1 | nucleic acid binding protein 1 | -0.0078608 |
| GOLGA2 | golgin A2 | -0.00780668 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.00779935 |
| CLASRP | CLK4-associating serine/arginine rich protein | -0.00775909 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.00775719 |
| OGA | O-GlcNAcase | -0.0077291 |
| TMEM41B | transmembrane protein 41B | -0.00766018 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) | -0.00765006 |
| GPC5 | glypican 5 | -0.00758095 |
| EVI5 | ecotropic viral integration site 5 | -0.00754097 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.00752321 |
| RAB7A | RAB7A, member RAS oncogene family | -0.00749554 |
| RPS12 | ribosomal protein S12 | -0.00741373 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.00738746 |
| PGM3 | phosphoglucomutase 3 | -0.00738431 |
| RPS27A | ribosomal protein S27a | -0.00738098 |
| SNX14 | sorting nexin 14 | -0.00730761 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.00729057 |
| RPS13 | ribosomal protein S13 | -0.00724936 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.00721499 |
| STPG4 | sperm-tail PG-rich repeat containing 4 | -0.00712336 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.00708601 |
| USP53 | ubiquitin specific peptidase 53 | -0.00694278 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.00693094 |
| TVP23C-CDRT4 | TVP23C-CDRT4 readthrough | -0.00690347 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.00684706 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | -0.00683391 |
| RBM39 | RNA binding motif protein 39 | -0.00682865 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | -0.00681045 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.00680899 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.00677852 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.00676015 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.00674927 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.00674713 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0067339 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 | -0.00668604 |
