| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Folic acid perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Folic acid_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.196723 |
| COL6A3 | collagen, type VI, alpha 3 | 0.178424 |
| CDH13 | cadherin 13 | 0.0971843 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.064053 |
| GLIS3 | GLIS family zinc finger 3 | 0.0397188 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.037245 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0368445 |
| COL5A1 | collagen, type V, alpha 1 | 0.0350117 |
| ASPH | aspartate beta-hydroxylase | 0.0332422 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0327178 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0305899 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0292786 |
| FBN1 | fibrillin 1 | 0.0269655 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0268919 |
| HMGA2 | high mobility group AT-hook 2 | 0.0268116 |
| RUNX1 | runt-related transcription factor 1 | 0.0253118 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.0247793 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0245464 |
| EFNA5 | ephrin-A5 | 0.0239377 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0237528 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0237228 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0209698 |
| SETBP1 | SET binding protein 1 | 0.0208481 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0208118 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0185023 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0184433 |
| PDE10A | phosphodiesterase 10A | 0.0183892 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0182961 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0182614 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0179177 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0176712 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0175458 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0173453 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0172848 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0172091 |
| NAV1 | neuron navigator 1 | 0.0171971 |
| EPHB1 | EPH receptor B1 | 0.0171242 |
| VEGFC | vascular endothelial growth factor C | 0.0170671 |
| NRP1 | neuropilin 1 | 0.016972 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0162308 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0159576 |
| FN1 | fibronectin 1 | 0.0155166 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.015217 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0146027 |
| ADAMTSL1 | ADAMTS-like 1 | 0.0133945 |
| HDAC9 | histone deacetylase 9 | 0.0133794 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0132402 |
| C1D | C1D nuclear receptor corepressor | 0.0132203 |
| SMYD3 | SET and MYND domain containing 3 | 0.0130183 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0128791 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0127889 |
| OSMR | oncostatin M receptor | 0.0127581 |
| SVIL | supervillin | 0.0126135 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0125702 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0124555 |
| FAT1 | FAT atypical cadherin 1 | 0.0122003 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0121983 |
| EXOC4 | exocyst complex component 4 | 0.0121391 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0121109 |
| PRKCA | protein kinase C, alpha | 0.011994 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0118501 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0116363 |
| DST | dystonin | 0.0111949 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0111627 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0110174 |
| KIAA1549L | KIAA1549-like | 0.0109853 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0107344 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0105562 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0104798 |
| CNTN5 | contactin 5 | 0.0102401 |
| RANBP17 | RAN binding protein 17 | 0.0101699 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0100181 |
| ATXN1 | ataxin 1 | 0.010007 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.00999852 |
| NOTCH2 | notch 2 | 0.00999529 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.00994558 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.00989707 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.00980514 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.00972989 |
| HMCN1 | hemicentin 1 | 0.00937728 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0091801 |
| DOCK5 | dedicator of cytokinesis 5 | 0.00916711 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0091356 |
| KLF12 | Kruppel-like factor 12 | 0.0091023 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.00906816 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.00889114 |
| NAV3 | neuron navigator 3 | 0.00886983 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00886189 |
| OXR1 | oxidation resistance 1 | 0.00884164 |
| FOXP1 | forkhead box P1 | 0.00872839 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.00866923 |
| VCL | vinculin | 0.0086131 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.00851672 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.00843007 |
| CPQ | carboxypeptidase Q | 0.00842379 |
| CFAP44 | cilia and flagella associated protein 44 | 0.008375 |
| PRRX1 | paired related homeobox 1 | 0.00835139 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.00833142 |
| FAM20C | family with sequence similarity 20, member C | 0.00830218 |
| TBC1D5 | TBC1 domain family, member 5 | 0.00829999 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.23745 |
| MT2A | metallothionein 2A | -0.174466 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.167188 |
| TMSB10 | thymosin beta 10 | -0.108603 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.105927 |
| COL1A2 | collagen, type I, alpha 2 | -0.101644 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0994452 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0919832 |
| COL1A1 | collagen, type I, alpha 1 | -0.0831086 |
| LDHA | lactate dehydrogenase A | -0.0821589 |
| IER3 | immediate early response 3 | -0.0806476 |
| PTMA | prothymosin, alpha | -0.0756245 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0752303 |
| FTL | ferritin, light polypeptide | -0.0714331 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0703819 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0691039 |
| RPS8 | ribosomal protein S8 | -0.0630553 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0614279 |
| STC1 | stanniocalcin 1 | -0.0612631 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0560158 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0557637 |
| NDRG1 | N-myc downstream regulated 1 | -0.0554425 |
| RPS6 | ribosomal protein S6 | -0.0530734 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0528438 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0508013 |
| ACTG1 | actin gamma 1 | -0.0497111 |
| RPL35A | ribosomal protein L35a | -0.0495453 |
| INHBA | inhibin, beta A | -0.0475823 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0453393 |
| TPM4 | tropomyosin 4 | -0.0449927 |
| HLA-B | major histocompatibility complex, class I, B | -0.0439029 |
| B2M | beta-2-microglobulin | -0.0434588 |
| SPAG9 | sperm associated antigen 9 | -0.0429705 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0428528 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0418224 |
| TMSB4X | thymosin beta 4, X-linked | -0.0417728 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0404258 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0397818 |
| GOLGA4 | golgin A4 | -0.0397357 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0392523 |
| MT1X | metallothionein 1X | -0.0392321 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0377436 |
| CAVIN1 | caveolae associated protein 1 | -0.0374676 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0371393 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0362764 |
| RRBP1 | ribosome binding protein 1 | -0.0361718 |
| CALR | calreticulin | -0.0361315 |
| CD44 | CD44 molecule (Indian blood group) | -0.0360844 |
| S100A9 | S100 calcium binding protein A9 | -0.0359859 |
| RPL11 | ribosomal protein L11 | -0.0357794 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0352793 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0343273 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0342535 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0340989 |
| RPL7 | ribosomal protein L7 | -0.0337804 |
| UBC | ubiquitin C | -0.0334778 |
| CADM1 | cell adhesion molecule 1 | -0.0332956 |
| PGK1 | phosphoglycerate kinase 1 | -0.0331847 |
| VEGFA | vascular endothelial growth factor A | -0.0330477 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0314719 |
| RPS19 | ribosomal protein S19 | -0.031189 |
| RAD21 | RAD21 homolog (S. pombe) | -0.031158 |
| MTDH | metadherin | -0.0307102 |
| RPL19 | ribosomal protein L19 | -0.0304112 |
| RPL26 | ribosomal protein L26 | -0.030288 |
| RPL12 | ribosomal protein L12 | -0.0301427 |
| RPL37A | ribosomal protein L37a | -0.030115 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0300695 |
| CANX | calnexin | -0.0300211 |
| LOXL2 | lysyl oxidase-like 2 | -0.0292065 |
| RPS2 | ribosomal protein S2 | -0.0290374 |
| RPL23 | ribosomal protein L23 | -0.0289714 |
| SEPTIN7 | septin 7 | -0.0289088 |
| S100A6 | S100 calcium binding protein A6 | -0.0286359 |
| S100A10 | S100 calcium binding protein A10 | -0.0286108 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0286092 |
| RPS3 | ribosomal protein S3 | -0.0284991 |
| RPS13 | ribosomal protein S13 | -0.0282427 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0279676 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0278868 |
| SQLE | squalene epoxidase | -0.0278818 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0276735 |
| RLF | rearranged L-myc fusion | -0.0270645 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0266722 |
| RPLP1 | ribosomal protein, large, P1 | -0.0266618 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0265994 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0265554 |
| VDAC1 | voltage-dependent anion channel 1 | -0.026398 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0262278 |
| ADM | adrenomedullin | -0.025969 |
| RPL8 | ribosomal protein L8 | -0.0254673 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0254012 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0250865 |
| GNAS | GNAS complex locus | -0.0248749 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0247866 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0246507 |
| RACK1 | receptor for activated C kinase 1 | -0.0246162 |
| POSTN | periostin, osteoblast specific factor | -0.0245224 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0242743 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0240713 |
