| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Folic acid perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Folic acid_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | 0.15802 |
| EGFR | epidermal growth factor receptor | 0.153427 |
| NDRG1 | N-myc downstream regulated 1 | 0.133655 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0939478 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0910299 |
| FAM13A | family with sequence similarity 13, member A | 0.0808001 |
| MCL1 | myeloid cell leukemia 1 | 0.0737936 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0704737 |
| SLTM | SAFB-like, transcription modulator | 0.0699016 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0623784 |
| SPAG9 | sperm associated antigen 9 | 0.0609844 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0597801 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0591232 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.055413 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0551959 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0520129 |
| SMAD3 | SMAD family member 3 | 0.0496771 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0486667 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0456177 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0451913 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0445824 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0439072 |
| CES1 | carboxylesterase 1 | 0.043771 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0423795 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0422605 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0419636 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0410024 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0404814 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0384436 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0378924 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0376004 |
| INTS6 | integrator complex subunit 6 | 0.0366948 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0362976 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0359912 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0357781 |
| PYGL | phosphorylase, glycogen, liver | 0.0351375 |
| PDE8A | phosphodiesterase 8A | 0.0349473 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0343335 |
| SMYD3 | SET and MYND domain containing 3 | 0.0342243 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0341253 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0341208 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0339431 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.033848 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0323855 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0322644 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.032117 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0320979 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0319598 |
| BMP6 | bone morphogenetic protein 6 | 0.0315968 |
| HELZ | helicase with zinc finger | 0.0310452 |
| KCMF1 | potassium channel modulatory factor 1 | 0.030962 |
| RUNX1 | runt-related transcription factor 1 | 0.0307978 |
| NGLY1 | N-glycanase 1 | 0.0306433 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0306151 |
| TES | testin LIM domain protein | 0.0305635 |
| ARRDC3 | arrestin domain containing 3 | 0.0292904 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0292314 |
| ZNF292 | zinc finger protein 292 | 0.0291868 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0291509 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.029131 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0287423 |
| CCNL1 | cyclin L1 | 0.0284573 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0284026 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0283653 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0282988 |
| ATP11A | ATPase, class VI, type 11A | 0.0282898 |
| ATXN1 | ataxin 1 | 0.0281729 |
| PCBP2 | poly(rC) binding protein 2 | 0.0273291 |
| PTEN | phosphatase and tensin homolog | 0.0270464 |
| POTEF | POTE ankyrin domain family, member F | 0.0269081 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0268916 |
| FNIP1 | folliculin interacting protein 1 | 0.0266114 |
| ATOSA | atos homolog A | 0.0261693 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0257338 |
| ANO6 | anoctamin 6 | 0.0256336 |
| CUL4A | cullin 4A | 0.0255594 |
| MSN | moesin | 0.0254968 |
| ARF4 | ADP-ribosylation factor 4 | 0.0252604 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0250856 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0249711 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0249551 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0248138 |
| YAP1 | Yes-associated protein 1 | 0.0247647 |
| GPHN | gephyrin | 0.0245907 |
| NBAS | neuroblastoma amplified sequence | 0.0245642 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0243837 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0239923 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0239439 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0236911 |
| UBC | ubiquitin C | 0.0233944 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.02322 |
| MORF4L2 | mortality factor 4 like 2 | 0.0230956 |
| PKM | pyruvate kinase, muscle | 0.023017 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0223303 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0221085 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.021696 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0214832 |
| MYO5B | myosin VB | 0.0214338 |
| RPL3 | ribosomal protein L3 | 0.0213047 |
| VEGFC | vascular endothelial growth factor C | 0.0212657 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.192871 |
| TMSB10 | thymosin beta 10 | -0.118345 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.111437 |
| TXNRD1 | thioredoxin reductase 1 | -0.098679 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0797692 |
| LAMC2 | laminin, gamma 2 | -0.0768021 |
| MT2A | metallothionein 2A | -0.0756212 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0684019 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0672991 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0640445 |
| S100A10 | S100 calcium binding protein A10 | -0.062518 |
| RNF213 | ring finger protein 213 | -0.0621443 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0612028 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0607576 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0599232 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.059737 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0589611 |
| LAMA4 | laminin, alpha 4 | -0.0552504 |
| B2M | beta-2-microglobulin | -0.0524984 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0509961 |
| ANXA2 | annexin A2 | -0.0509468 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0443703 |
| CST3 | cystatin C | -0.0440644 |
| AHNAK | AHNAK nucleoprotein | -0.043962 |
| STC1 | stanniocalcin 1 | -0.0420295 |
| DSPP | dentin sialophosphoprotein | -0.0419994 |
| ACTG1 | actin gamma 1 | -0.0418584 |
| RIGI | RNA sensor RIG-I | -0.0416901 |
| CCND1 | cyclin D1 | -0.041459 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0411933 |
| PTMA | prothymosin, alpha | -0.0394478 |
| TRIM56 | tripartite motif containing 56 | -0.0393496 |
| RPS3 | ribosomal protein S3 | -0.0374313 |
| HLA-B | major histocompatibility complex, class I, B | -0.037339 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0371189 |
| KRT8 | keratin 8, type II | -0.0371096 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0365668 |
| SEC61G | Sec61 gamma subunit | -0.035814 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0357184 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0332581 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0331758 |
| SP100 | SP100 nuclear antigen | -0.0324155 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0321961 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0321044 |
| KRT18 | keratin 18, type I | -0.0319759 |
| RPL34 | ribosomal protein L34 | -0.0319414 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.031895 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0318537 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.031593 |
| FTL | ferritin, light polypeptide | -0.0311689 |
| RPS24 | ribosomal protein S24 | -0.0308676 |
| RAB10 | RAB10, member RAS oncogene family | -0.0307567 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0307309 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0304262 |
| TAOK3 | TAO kinase 3 | -0.0294809 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0290609 |
| MYOF | myoferlin | -0.028742 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0286051 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0283144 |
| MT1X | metallothionein 1X | -0.0282729 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0274932 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0274015 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0273966 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0273828 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0269818 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0267769 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.026515 |
| KRT7 | keratin 7, type II | -0.0263295 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0262496 |
| LDHA | lactate dehydrogenase A | -0.0262342 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0261753 |
| PGK1 | phosphoglycerate kinase 1 | -0.0260016 |
| TNS3 | tensin 3 | -0.0258976 |
| PMP22 | peripheral myelin protein 22 | -0.0256348 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0253032 |
| LAMB3 | laminin, beta 3 | -0.0252672 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.025251 |
| MX1 | MX dynamin-like GTPase 1 | -0.0251953 |
| EPCAM | epithelial cell adhesion molecule | -0.0248782 |
| KRT19 | keratin 19, type I | -0.0241923 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0240715 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0239594 |
| CP | ceruloplasmin (ferroxidase) | -0.0239241 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0236932 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0236782 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.023566 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0233474 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.023227 |
| GM2A | GM2 ganglioside activator | -0.023147 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0231344 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0229544 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.02281 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0226349 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0221666 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0221223 |
| MCU | mitochondrial calcium uniporter | -0.0220017 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0217494 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0215042 |
| CTSL | cathepsin L | -0.0213879 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0212813 |
