| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Folic acid perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Folic acid_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.128288 |
| LOX | lysyl oxidase | 0.0877783 |
| CDH13 | cadherin 13 | 0.084848 |
| EFNA5 | ephrin-A5 | 0.0824214 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0813275 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0764712 |
| FN1 | fibronectin 1 | 0.0736579 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0725948 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.065269 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0626397 |
| SYT1 | synaptotagmin I | 0.0584421 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0567056 |
| SMAD3 | SMAD family member 3 | 0.0506628 |
| NAV2 | neuron navigator 2 | 0.0505126 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0491162 |
| NRP1 | neuropilin 1 | 0.0482726 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0476037 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0468723 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0453277 |
| NRG1 | neuregulin 1 | 0.0444352 |
| MEF2A | myocyte enhancer factor 2A | 0.0415788 |
| HMGA2 | high mobility group AT-hook 2 | 0.0403978 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0390466 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0376978 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0371069 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0362356 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0354205 |
| VEGFC | vascular endothelial growth factor C | 0.0332543 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0326097 |
| RPL35A | ribosomal protein L35a | 0.0322537 |
| RUNX1 | runt-related transcription factor 1 | 0.0321318 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0319295 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0315634 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0315518 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.031246 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0312176 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0311338 |
| EXOC4 | exocyst complex component 4 | 0.0309894 |
| ASPH | aspartate beta-hydroxylase | 0.0308715 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.030285 |
| CDCP1 | CUB domain containing protein 1 | 0.0300927 |
| TGM2 | transglutaminase 2 | 0.0300609 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.029711 |
| NTN4 | netrin 4 | 0.0292405 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.029182 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0291181 |
| ARFGEF3 | ARFGEF family member 3 | 0.029039 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0288544 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0272077 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0271304 |
| DOCK5 | dedicator of cytokinesis 5 | 0.026924 |
| AHNAK | AHNAK nucleoprotein | 0.0266236 |
| RPS25 | ribosomal protein S25 | 0.02598 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0258845 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0257908 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0255206 |
| SEPTIN9 | septin 9 | 0.0253488 |
| INTS6 | integrator complex subunit 6 | 0.0252459 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0251431 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0247261 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0245452 |
| CA12 | carbonic anhydrase XII | 0.0245273 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0243633 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0240865 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.024045 |
| ETV6 | ets variant 6 | 0.0240188 |
| SUMF1 | sulfatase modifying factor 1 | 0.0238936 |
| IL6ST | interleukin 6 signal transducer | 0.0238926 |
| ATXN1 | ataxin 1 | 0.0236856 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0235423 |
| PRKCA | protein kinase C, alpha | 0.0234883 |
| PFKP | phosphofructokinase, platelet | 0.0234199 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0233369 |
| SSH2 | slingshot protein phosphatase 2 | 0.0224049 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0221749 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0221093 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0221058 |
| CDK14 | cyclin-dependent kinase 14 | 0.0220786 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0220752 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0220688 |
| GLIS3 | GLIS family zinc finger 3 | 0.0219278 |
| GLCCI1 | glucocorticoid induced 1 | 0.0217936 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0213986 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0208302 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | 0.0208109 |
| RAI14 | retinoic acid induced 14 | 0.0207045 |
| PCBP2 | poly(rC) binding protein 2 | 0.020511 |
| RUNX2 | runt-related transcription factor 2 | 0.020365 |
| RPL31 | ribosomal protein L31 | 0.0202781 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0202116 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | 0.0201917 |
| FBN1 | fibrillin 1 | 0.0201508 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0201319 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0201183 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0201002 |
| DST | dystonin | 0.0200751 |
| ATP9A | ATPase, class II, type 9A | 0.0198376 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0197942 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0196081 |
| STAC | SH3 and cysteine rich domain | 0.0194967 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0986651 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0602115 |
| S100A6 | S100 calcium binding protein A6 | -0.0595907 |
| STC1 | stanniocalcin 1 | -0.0544569 |
| TMSB10 | thymosin beta 10 | -0.0534618 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0498582 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0496835 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0487559 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0467239 |
| B2M | beta-2-microglobulin | -0.0465383 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0458089 |
| IER3 | immediate early response 3 | -0.0444092 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0426925 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0426556 |
| VIM | vimentin | -0.040887 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0398513 |
| MT2A | metallothionein 2A | -0.039146 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0383446 |
| TMSB4X | thymosin beta 4, X-linked | -0.0381939 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0373089 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0363053 |
| RPLP1 | ribosomal protein, large, P1 | -0.0355886 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0353139 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0346734 |
| JMJD1C | jumonji domain containing 1C | -0.0344175 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0341388 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0336472 |
| HLA-B | major histocompatibility complex, class I, B | -0.0326609 |
| PTMA | prothymosin, alpha | -0.0321221 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0314909 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0307658 |
| RPS12 | ribosomal protein S12 | -0.030134 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0281251 |
| TMEM263 | transmembrane protein 263 | -0.0280734 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0275599 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.0272309 |
| RBM25 | RNA binding motif protein 25 | -0.0268065 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0267815 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0263134 |
| ANXA1 | annexin A1 | -0.0262851 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0250148 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0244807 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0241322 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0240844 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0239673 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.023949 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0238035 |
| OSMR | oncostatin M receptor | -0.0236187 |
| RPS21 | ribosomal protein S21 | -0.0232655 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0232474 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | -0.0232386 |
| USP15 | ubiquitin specific peptidase 15 | -0.0229126 |
| MIDN | midnolin | -0.0226414 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0225628 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0216816 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.0215232 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0214158 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0213252 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0213062 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.021292 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0212801 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0212796 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0212536 |
| S100A10 | S100 calcium binding protein A10 | -0.0209899 |
| TNNC1 | troponin C type 1 (slow) | -0.0208509 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0205195 |
| RNF24 | ring finger protein 24 | -0.0205167 |
| RPL34 | ribosomal protein L34 | -0.0205049 |
| KLF6 | Kruppel-like factor 6 | -0.0204125 |
| NF1 | neurofibromin 1 | -0.0203535 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0202731 |
| USP34 | ubiquitin specific peptidase 34 | -0.0202539 |
| RPS24 | ribosomal protein S24 | -0.0201269 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0201109 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0200876 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0200158 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0199187 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0197272 |
| DUSP6 | dual specificity phosphatase 6 | -0.0196862 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0194328 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0193732 |
| HAS2 | hyaluronan synthase 2 | -0.0193239 |
| YBX3 | Y box binding protein 3 | -0.0193061 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0191745 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0191345 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0191079 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.018964 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0189516 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0189186 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0188055 |
| MT1X | metallothionein 1X | -0.0187922 |
| RBM39 | RNA binding motif protein 39 | -0.0187692 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0187532 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0186581 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0185166 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0184682 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0183991 |
| EEA1 | early endosome antigen 1 | -0.0183815 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0183703 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0183701 |
