| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Folic acid perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Folic acid_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.226866 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.160314 |
| MCL1 | myeloid cell leukemia 1 | 0.113182 |
| PM20D1 | peptidase M20 domain containing 1 | 0.10657 |
| FTL | ferritin, light polypeptide | 0.0962456 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0921185 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0754113 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0609674 |
| WWOX | WW domain containing oxidoreductase | 0.0559628 |
| POTEF | POTE ankyrin domain family, member F | 0.054583 |
| GRAMD1B | GRAM domain containing 1B | 0.0533972 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0528473 |
| PCBP2 | poly(rC) binding protein 2 | 0.0485281 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0479381 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0454845 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0453224 |
| CCNL1 | cyclin L1 | 0.0429118 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0394651 |
| PFN1 | profilin 1 | 0.0388995 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0385355 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0384988 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0383271 |
| RPL3 | ribosomal protein L3 | 0.0381491 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0372723 |
| BMP6 | bone morphogenetic protein 6 | 0.0370205 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0366508 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0351274 |
| RTN4 | reticulon 4 | 0.0348219 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0339669 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.033781 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0334838 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0330193 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0330133 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0329245 |
| BRD2 | bromodomain containing 2 | 0.0325516 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0320296 |
| PKM | pyruvate kinase, muscle | 0.0313289 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0313118 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0312304 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0306322 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0301694 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0300875 |
| FLNA | filamin A, alpha | 0.0300659 |
| VMP1 | vacuole membrane protein 1 | 0.0289707 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0289386 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0288785 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0286661 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.0282122 |
| PDE8A | phosphodiesterase 8A | 0.0279207 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0276603 |
| ZNF292 | zinc finger protein 292 | 0.0270908 |
| RUNX1 | runt-related transcription factor 1 | 0.0269336 |
| TPM3 | tropomyosin 3 | 0.0265725 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0265193 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0265138 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0264533 |
| ATXN1 | ataxin 1 | 0.0261181 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0260718 |
| FMNL2 | formin-like 2 | 0.0254867 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0249458 |
| ATP11A | ATPase, class VI, type 11A | 0.0245901 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0245708 |
| MTMR3 | myotubularin related protein 3 | 0.0243948 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0242786 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0240697 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0239766 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0236311 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0235487 |
| PDE10A | phosphodiesterase 10A | 0.0234542 |
| MSN | moesin | 0.0234296 |
| YBX1 | Y box binding protein 1 | 0.0227403 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0225013 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0222006 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0220582 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0220526 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0216946 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0216108 |
| COPA | coatomer protein complex, subunit alpha | 0.0215843 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0213351 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0211991 |
| MRTFA | myocardin related transcription factor A | 0.0210363 |
| DIAPH1 | diaphanous-related formin 1 | 0.0209953 |
| MYOF | myoferlin | 0.0209304 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | 0.0208278 |
| RNF145 | ring finger protein 145 | 0.0206062 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0205271 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.020306 |
| KIAA0319 | KIAA0319 | 0.020245 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0200169 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0199897 |
| PLS3 | plastin 3 | 0.0198545 |
| TPD52 | tumor protein D52 | 0.0197482 |
| YAP1 | Yes-associated protein 1 | 0.0197308 |
| FGB | fibrinogen beta chain | 0.0196914 |
| NXF1 | nuclear RNA export factor 1 | 0.0196031 |
| DENND4A | DENN/MADD domain containing 4A | 0.0191912 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0191768 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0190482 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.018914 |
| ZNF277 | zinc finger protein 277 | 0.0188284 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.178034 |
| MT2A | metallothionein 2A | -0.0895721 |
| IER3 | immediate early response 3 | -0.0793163 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0771328 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0760343 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0726622 |
| TXNRD1 | thioredoxin reductase 1 | -0.0720179 |
| CAVIN1 | caveolae associated protein 1 | -0.0708476 |
| ACTG1 | actin gamma 1 | -0.0688011 |
| ERBIN | erbb2 interacting protein | -0.0671218 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0652591 |
| STC1 | stanniocalcin 1 | -0.0644013 |
| PTMA | prothymosin, alpha | -0.0636087 |
| HDAC9 | histone deacetylase 9 | -0.0629204 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0606233 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0553334 |
| LDHA | lactate dehydrogenase A | -0.0519522 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0482276 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.041847 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0402158 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0400999 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0393707 |
| AHNAK | AHNAK nucleoprotein | -0.0391447 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0390929 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0390892 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0385397 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0366625 |
| RPS27A | ribosomal protein S27a | -0.0355087 |
| RPL37A | ribosomal protein L37a | -0.0351632 |
| IGF2 | insulin-like growth factor 2 | -0.0348318 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0344537 |
| EGFR | epidermal growth factor receptor | -0.0342283 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.033383 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0331242 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0324553 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0316355 |
| S100A6 | S100 calcium binding protein A6 | -0.0316314 |
| KIF5B | kinesin family member 5B | -0.0315355 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0313036 |
| RPL23 | ribosomal protein L23 | -0.0312942 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0311111 |
| WDR43 | WD repeat domain 43 | -0.0309988 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0309701 |
| RPS24 | ribosomal protein S24 | -0.0307183 |
| THBS1 | thrombospondin 1 | -0.0306971 |
| TPM4 | tropomyosin 4 | -0.0303485 |
| ENO1 | enolase 1, (alpha) | -0.0302532 |
| RPS8 | ribosomal protein S8 | -0.0298618 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.029761 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0296944 |
| RPL31 | ribosomal protein L31 | -0.0291826 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0291456 |
| AK1 | adenylate kinase 1 | -0.0291006 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0290831 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0284547 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0281383 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0280428 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0280259 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0279738 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0273912 |
| S100A10 | S100 calcium binding protein A10 | -0.0273573 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0270931 |
| RAB10 | RAB10, member RAS oncogene family | -0.0263147 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0248886 |
| HLA-B | major histocompatibility complex, class I, B | -0.0247331 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0246808 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0245176 |
| NRG1 | neuregulin 1 | -0.0244737 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0244228 |
| RPL34 | ribosomal protein L34 | -0.0240418 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0239073 |
| ZFHX3 | zinc finger homeobox 3 | -0.0237458 |
| SEPTIN7 | septin 7 | -0.0237121 |
| SRGN | serglycin | -0.0236568 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0232348 |
| HLA-E | major histocompatibility complex, class I, E | -0.0230108 |
| VCL | vinculin | -0.02285 |
| MAP1B | microtubule-associated protein 1B | -0.0225033 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0223824 |
| TRIP11 | thyroid hormone receptor interactor 11 | -0.0222956 |
| RASAL2 | RAS protein activator like 2 | -0.0221571 |
| CDK12 | cyclin-dependent kinase 12 | -0.0221067 |
| PGK1 | phosphoglycerate kinase 1 | -0.0220945 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0219467 |
| RPL26 | ribosomal protein L26 | -0.021383 |
| SVIL | supervillin | -0.0208743 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0207736 |
| RPL11 | ribosomal protein L11 | -0.0207727 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0207208 |
| HMGA2 | high mobility group AT-hook 2 | -0.0202156 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0202099 |
| BICC1 | BicC family RNA binding protein 1 | -0.0200802 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0199007 |
| CENPF | centromere protein F, 350/400kDa | -0.019824 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0197152 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0197043 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0196717 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0195584 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0193836 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0193428 |
