| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Folic acid perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Folic acid_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM2 | cell adhesion molecule 2 | 0.101691 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0805539 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0801726 |
| PRTG | protogenin | 0.0601981 |
| FOXP2 | forkhead box P2 | 0.0589353 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0584825 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0582055 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0577766 |
| PCDH9 | protocadherin 9 | 0.0554775 |
| DST | dystonin | 0.0550392 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0542615 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | 0.0542293 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.051209 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0501458 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0496169 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0474883 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0462916 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0454472 |
| PHIP | pleckstrin homology domain interacting protein | 0.0428717 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0414019 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0407568 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0398617 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0394664 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0367697 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0366094 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 | 0.0362156 |
| PLPP1 | phospholipid phosphatase 1 | 0.035127 |
| PEG10 | paternally expressed 10 | 0.0349343 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0348592 |
| LYST | lysosomal trafficking regulator | 0.0347637 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0337939 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0334768 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0333754 |
| ZNF608 | zinc finger protein 608 | 0.0332075 |
| ANK2 | ankyrin 2, neuronal | 0.0329198 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0324502 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.0321668 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0317202 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0313374 |
| ENAH | enabled homolog (Drosophila) | 0.0308331 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0304803 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0304497 |
| DENND4A | DENN/MADD domain containing 4A | 0.0303412 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0295214 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0290591 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0277408 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0277371 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0270577 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0265823 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0265329 |
| PCDH18 | protocadherin 18 | 0.0262384 |
| MED12L | mediator complex subunit 12-like | 0.0254664 |
| ITSN2 | intersectin 2 | 0.0250546 |
| ERBIN | erbb2 interacting protein | 0.0241901 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0238143 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.0235543 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0225665 |
| RBM20 | RNA binding motif protein 20 | 0.0225252 |
| CDH19 | cadherin 19, type 2 | 0.0224146 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0221206 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0220907 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | 0.0220061 |
| RREB1 | ras responsive element binding protein 1 | 0.0218856 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0213836 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0213745 |
| MDFIC | MyoD family inhibitor domain containing | 0.0212263 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0211141 |
| PALLD | palladin, cytoskeletal associated protein | 0.0207357 |
| NPAS3 | neuronal PAS domain protein 3 | 0.020669 |
| UBE3C | ubiquitin protein ligase E3C | 0.0204652 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0199812 |
| TLK2 | tousled-like kinase 2 | 0.0196529 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0195615 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0195405 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0194603 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0193618 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0192922 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0192438 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0190322 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0190258 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0188587 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0186271 |
| USP53 | ubiquitin specific peptidase 53 | 0.0186242 |
| TENM3 | teneurin transmembrane protein 3 | 0.0184083 |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.0183764 |
| HDAC9 | histone deacetylase 9 | 0.0181881 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.018152 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0181187 |
| UTRN | utrophin | 0.0180946 |
| LPIN2 | lipin 2 | 0.0179087 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | 0.017907 |
| MED13L | mediator complex subunit 13-like | 0.0178756 |
| TGFB2 | transforming growth factor, beta 2 | 0.0177756 |
| MEF2C | myocyte enhancer factor 2C | 0.0177153 |
| DNAH11 | dynein, axonemal, heavy chain 11 | 0.0176269 |
| INTS6 | integrator complex subunit 6 | 0.0175004 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0173865 |
| ZNF292 | zinc finger protein 292 | 0.0172776 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0172235 |
| DENND1A | DENN/MADD domain containing 1A | 0.0169755 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.190613 |
| PTMA | prothymosin, alpha | -0.163896 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.162557 |
| TMSB10 | thymosin beta 10 | -0.111462 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0955556 |
| RPS16 | ribosomal protein S16 | -0.0888614 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.087476 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0830167 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0653506 |
| RPL19 | ribosomal protein L19 | -0.0628812 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0623399 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0617116 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0608653 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.058138 |
| ACTG1 | actin gamma 1 | -0.057894 |
| RPS6 | ribosomal protein S6 | -0.0577971 |
| RPL31 | ribosomal protein L31 | -0.0564747 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0560994 |
| TMSB4X | thymosin beta 4, X-linked | -0.0560001 |
| RPL35A | ribosomal protein L35a | -0.0550173 |
| RPS8 | ribosomal protein S8 | -0.0536287 |
| RPL11 | ribosomal protein L11 | -0.0526059 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0521908 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0497235 |
| GNAS | GNAS complex locus | -0.0487797 |
| CALR | calreticulin | -0.0480578 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0462902 |
| RPS25 | ribosomal protein S25 | -0.0453152 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.044856 |
| B2M | beta-2-microglobulin | -0.044272 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0438789 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0435391 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0431301 |
| RPLP0 | ribosomal protein, large, P0 | -0.042529 |
| RPS21 | ribosomal protein S21 | -0.0405006 |
| RPS24 | ribosomal protein S24 | -0.0398664 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0391981 |
| RTN4 | reticulon 4 | -0.038941 |
| RPL12 | ribosomal protein L12 | -0.0376596 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0376373 |
| FTL | ferritin, light polypeptide | -0.0376291 |
| DEK | DEK proto-oncogene | -0.037308 |
| RPL23 | ribosomal protein L23 | -0.036974 |
| RPL34 | ribosomal protein L34 | -0.0368641 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0367358 |
| MKI67 | marker of proliferation Ki-67 | -0.0366581 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.0357524 |
| AHNAK | AHNAK nucleoprotein | -0.0356363 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.035392 |
| RPS19 | ribosomal protein S19 | -0.0353622 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0351231 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0350491 |
| PGK1 | phosphoglycerate kinase 1 | -0.0341421 |
| RACK1 | receptor for activated C kinase 1 | -0.0341122 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0338713 |
| RPS13 | ribosomal protein S13 | -0.0336532 |
| RPS2 | ribosomal protein S2 | -0.0329251 |
| RPLP1 | ribosomal protein, large, P1 | -0.0321536 |
| HMGB1 | high mobility group box 1 | -0.0320098 |
| SPAG9 | sperm associated antigen 9 | -0.0319958 |
| COL3A1 | collagen, type III, alpha 1 | -0.0319864 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0319846 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0319591 |
| CBX3 | chromobox homolog 3 | -0.031955 |
| RPL37A | ribosomal protein L37a | -0.0316187 |
| MORF4L2 | mortality factor 4 like 2 | -0.0309186 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0306276 |
| LDHA | lactate dehydrogenase A | -0.0304509 |
| KIF5B | kinesin family member 5B | -0.0300326 |
| NTM | neurotrimin | -0.0298543 |
| RPL37 | ribosomal protein L37 | -0.0294061 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0292752 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0292559 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0289665 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0288995 |
| RPS12 | ribosomal protein S12 | -0.0288067 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0286332 |
| TUBB | tubulin, beta class I | -0.0282323 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0281153 |
| SGO2 | shugoshin 2 | -0.0280526 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0276542 |
| PFN1 | profilin 1 | -0.0272973 |
| SRP72 | signal recognition particle 72kDa | -0.0270434 |
| RPS27A | ribosomal protein S27a | -0.0269803 |
| RSF1 | remodeling and spacing factor 1 | -0.0268356 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0265849 |
| EMP1 | epithelial membrane protein 1 | -0.0265608 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0260409 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | -0.0258616 |
| RPS3 | ribosomal protein S3 | -0.0257076 |
| CANX | calnexin | -0.0254316 |
| MATR3 | matrin 3 | -0.0254206 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0251764 |
| RPL18 | ribosomal protein L18 | -0.0251411 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0250872 |
| RDX | radixin | -0.0250369 |
| RPL28 | ribosomal protein L28 | -0.0250105 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0248715 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0246897 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | -0.0245349 |
