| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Folic acid perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Folic acid_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZFP36 | ZFP36 ring finger protein | 0.126394 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.111396 |
| JMJD1C | jumonji domain containing 1C | 0.110338 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.105334 |
| CD44 | CD44 molecule (Indian blood group) | 0.101903 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0998904 |
| RTN4 | reticulon 4 | 0.0969484 |
| VMP1 | vacuole membrane protein 1 | 0.0920588 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0830019 |
| TXNRD1 | thioredoxin reductase 1 | 0.0694064 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0645731 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0621439 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0593782 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.058374 |
| ASPH | aspartate beta-hydroxylase | 0.0576562 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0576544 |
| FOSL1 | FOS-like antigen 1 | 0.055036 |
| ACTN4 | actinin, alpha 4 | 0.0521113 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0515857 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0501443 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.049459 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0486567 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0462628 |
| CDK19 | cyclin-dependent kinase 19 | 0.0460566 |
| TMEM41B | transmembrane protein 41B | 0.0459001 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.045774 |
| DNMBP | dynamin binding protein | 0.0455679 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0444915 |
| MED13L | mediator complex subunit 13-like | 0.0443349 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0433995 |
| IL6ST | interleukin 6 signal transducer | 0.0426564 |
| FHL2 | four and a half LIM domains 2 | 0.0425944 |
| ITGB5 | integrin, beta 5 | 0.0420912 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0417661 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0415665 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0411143 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0404466 |
| SMYD3 | SET and MYND domain containing 3 | 0.0400083 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0391159 |
| FAM3C | family with sequence similarity 3, member C | 0.0389058 |
| RPL3 | ribosomal protein L3 | 0.038738 |
| EFNA5 | ephrin-A5 | 0.0382634 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0381445 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0370254 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0365156 |
| PTEN | phosphatase and tensin homolog | 0.0348422 |
| SMAD3 | SMAD family member 3 | 0.0348278 |
| YAP1 | Yes-associated protein 1 | 0.0346862 |
| SNX9 | sorting nexin 9 | 0.0346275 |
| ATP13A3 | ATPase type 13A3 | 0.0342122 |
| ANXA2 | annexin A2 | 0.0338896 |
| SESN2 | sestrin 2 | 0.0335036 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0327741 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0325651 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0324439 |
| ARRDC3 | arrestin domain containing 3 | 0.0317792 |
| SFTPA2 | surfactant protein A2 | 0.0317393 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0312866 |
| AFAP1 | actin filament associated protein 1 | 0.0309265 |
| MSN | moesin | 0.0307526 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0307032 |
| MKI67 | marker of proliferation Ki-67 | 0.0304409 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0300658 |
| POTEF | POTE ankyrin domain family, member F | 0.0300357 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0298268 |
| ITGAV | integrin, alpha V | 0.0288824 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0287551 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0287467 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0287282 |
| CDCP1 | CUB domain containing protein 1 | 0.0284086 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0283353 |
| MCL1 | myeloid cell leukemia 1 | 0.0283179 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0279253 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0277874 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0277151 |
| PDE10A | phosphodiesterase 10A | 0.0274201 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0272273 |
| FAT1 | FAT atypical cadherin 1 | 0.0269608 |
| IPO7 | importin 7 | 0.026843 |
| BCL2L1 | BCL2-like 1 | 0.0263813 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.026211 |
| ZNF292 | zinc finger protein 292 | 0.0259828 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0258959 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0256187 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0253255 |
| RNF145 | ring finger protein 145 | 0.0252679 |
| ENO1 | enolase 1, (alpha) | 0.025144 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0247978 |
| CARD18 | caspase recruitment domain family, member 18 | 0.0244017 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.024209 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0241391 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0240354 |
| PTK2 | protein tyrosine kinase 2 | 0.0239859 |
| ANO6 | anoctamin 6 | 0.0238158 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0229783 |
| TGOLN2 | trans-golgi network protein 2 | 0.0229518 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0228842 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0227315 |
| PCBP2 | poly(rC) binding protein 2 | 0.0226258 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | 0.0225109 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.186104 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.174931 |
| AHNAK | AHNAK nucleoprotein | -0.136092 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.123454 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.111871 |
| PTMA | prothymosin, alpha | -0.102323 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0911138 |
| TMSB10 | thymosin beta 10 | -0.0683098 |
| RPS16 | ribosomal protein S16 | -0.0664342 |
| INTS6 | integrator complex subunit 6 | -0.0613218 |
| CANX | calnexin | -0.0593114 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0586617 |
| MYOF | myoferlin | -0.0544365 |
| RPS24 | ribosomal protein S24 | -0.0529121 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0509277 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0476906 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0450941 |
| RPL35A | ribosomal protein L35a | -0.0440904 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0435577 |
| SPAG9 | sperm associated antigen 9 | -0.0418108 |
| ATG7 | autophagy related 7 | -0.0385887 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0376269 |
| CAVIN1 | caveolae associated protein 1 | -0.0374874 |
| MORF4L2 | mortality factor 4 like 2 | -0.0359162 |
| TNS3 | tensin 3 | -0.0332862 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0325745 |
| LDHA | lactate dehydrogenase A | -0.0309527 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0308503 |
| SEPTIN7 | septin 7 | -0.0308367 |
| NEK10 | NIMA-related kinase 10 | -0.0304622 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0298362 |
| CDK13 | cyclin-dependent kinase 13 | -0.0291912 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0290408 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.028927 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0287222 |
| HMGA2 | high mobility group AT-hook 2 | -0.0284872 |
| RPL38 | ribosomal protein L38 | -0.0280441 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0278486 |
| CTSD | cathepsin D | -0.0277559 |
| RNF220 | ring finger protein 220 | -0.0276855 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.027589 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.027468 |
| MYO1E | myosin IE | -0.027056 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0269932 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0269206 |
| NAV2 | neuron navigator 2 | -0.0267833 |
| HMGB1 | high mobility group box 1 | -0.0267596 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0265999 |
| ACTG1 | actin gamma 1 | -0.0265046 |
| RPS27A | ribosomal protein S27a | -0.0261717 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0261402 |
| GOLGB1 | golgin B1 | -0.0260363 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0259864 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0258338 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0256167 |
| CALR | calreticulin | -0.025541 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0253647 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0250405 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0247116 |
| DIAPH2 | diaphanous-related formin 2 | -0.0242614 |
| RPL11 | ribosomal protein L11 | -0.0240859 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.023784 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0232488 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0229991 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.0229044 |
| NF1 | neurofibromin 1 | -0.0228705 |
| EHBP1 | EH domain binding protein 1 | -0.0227953 |
| ZNF546 | zinc finger protein 546 | -0.0227863 |
| CTBP2 | C-terminal binding protein 2 | -0.0227756 |
| ARF1 | ADP-ribosylation factor 1 | -0.0226148 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0222002 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0221355 |
| STPG4 | sperm-tail PG-rich repeat containing 4 | -0.0220902 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0220193 |
| FBL | fibrillarin | -0.0220116 |
| FTL | ferritin, light polypeptide | -0.0219524 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0216737 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0213706 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0211276 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0210891 |
| S100A6 | S100 calcium binding protein A6 | -0.021026 |
| S100A10 | S100 calcium binding protein A10 | -0.0209931 |
| HDLBP | high density lipoprotein binding protein | -0.0207277 |
| CMIP | c-Maf inducing protein | -0.0206987 |
| TMEM123 | transmembrane protein 123 | -0.0206907 |
| ATM | ATM serine/threonine kinase | -0.0206315 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0203667 |
| RDX | radixin | -0.0203586 |
| IER3 | immediate early response 3 | -0.0203286 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.020172 |
| PGK1 | phosphoglycerate kinase 1 | -0.0201452 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0201132 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0200132 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0200007 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0199047 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0196929 |
| GOLGA3 | golgin A3 | -0.0195919 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0195334 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0194497 |
| RSU1 | Ras suppressor protein 1 | -0.0193286 |
