| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Folic acid perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Folic acid_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | 0.156191 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0691152 |
| NRG1 | neuregulin 1 | 0.049164 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0478339 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0395686 |
| SNTG1 | syntrophin, gamma 1 | 0.0395133 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0362829 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0355929 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0349163 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.034162 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0333497 |
| PCBP3 | poly(rC) binding protein 3 | 0.0330765 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0312947 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0308653 |
| SMYD3 | SET and MYND domain containing 3 | 0.0308417 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0301225 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0300744 |
| LSAMP | limbic system-associated membrane protein | 0.0300189 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | 0.029713 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0271686 |
| NBEA | neurobeachin | 0.0270286 |
| VGF | VGF nerve growth factor inducible | 0.0264137 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0260417 |
| AUTS2 | autism susceptibility candidate 2 | 0.0244096 |
| KIF26B | kinesin family member 26B | 0.0241217 |
| KCTD8 | potassium channel tetramerization domain containing 8 | 0.0237377 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0232203 |
| EFNA5 | ephrin-A5 | 0.0231728 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.023117 |
| COL22A1 | collagen, type XXII, alpha 1 | 0.0226183 |
| AOPEP | aminopeptidase O (putative) | 0.0213937 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.020809 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0207997 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0206037 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0197596 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0196003 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0194679 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.019053 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0190274 |
| AGBL4 | ATP/GTP binding protein-like 4 | 0.0189583 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0188948 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0184368 |
| GPC5 | glypican 5 | 0.0184234 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0183653 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0180231 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.018014 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0179713 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.01794 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0178965 |
| UNC79 | unc-79 homolog (C. elegans) | 0.0171562 |
| SCFD2 | sec1 family domain containing 2 | 0.0170435 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0167354 |
| DIDO1 | death inducer-obliterator 1 | 0.0166103 |
| ASIC2 | acid sensing (proton gated) ion channel 2 | 0.0165518 |
| ESRRG | estrogen-related receptor gamma | 0.0164025 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0163037 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0162361 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0159601 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0157009 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0155754 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | 0.0154535 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0154049 |
| FOCAD | focadhesin | 0.0151604 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0151326 |
| RORA | RAR-related orphan receptor A | 0.0151263 |
| SNX13 | sorting nexin 13 | 0.0151184 |
| GPC6 | glypican 6 | 0.0147405 |
| DST | dystonin | 0.014734 |
| CTBP2 | C-terminal binding protein 2 | 0.0145831 |
| UBAC2 | UBA domain containing 2 | 0.0145606 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0143667 |
| GPAT4 | glycerol-3-phosphate acyltransferase 4 | 0.0142175 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | 0.014134 |
| CEP95 | centrosomal protein 95kDa | 0.0140883 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0140732 |
| PAEP | progestagen-associated endometrial protein | 0.0140573 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0139246 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0139057 |
| VWA8 | von Willebrand factor A domain containing 8 | 0.0138513 |
| STXBP5L | syntaxin binding protein 5-like | 0.0138295 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0138206 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.0138159 |
| RIMBP2 | RIMS binding protein 2 | 0.0137138 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0136422 |
| UNC80 | unc-80 homolog (C. elegans) | 0.0135974 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0135023 |
| WDR70 | WD repeat domain 70 | 0.0134809 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0134137 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0133524 |
| FNIP1 | folliculin interacting protein 1 | 0.0132134 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0131694 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0131126 |
| TMEM255B | transmembrane protein 255B | 0.013008 |
| KLHL29 | kelch-like family member 29 | 0.0128405 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0128082 |
| GSE1 | Gse1 coiled-coil protein | 0.0127927 |
| FAM120B | family with sequence similarity 120B | 0.0127772 |
| PRKD1 | protein kinase D1 | 0.0127218 |
| GPRIN3 | GPRIN family member 3 | 0.0126243 |
| SETBP1 | SET binding protein 1 | 0.0126061 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.24534 |
| PTMA | prothymosin, alpha | -0.16493 |
| CALCA | calcitonin-related polypeptide alpha | -0.133748 |
| TENM1 | teneurin transmembrane protein 1 | -0.113514 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.106076 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0976659 |
| CENPF | centromere protein F, 350/400kDa | -0.086206 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0814142 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0805623 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0755368 |
| FTL | ferritin, light polypeptide | -0.0726953 |
| RPS6 | ribosomal protein S6 | -0.0628132 |
| ENO1 | enolase 1, (alpha) | -0.0573035 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0556454 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0511254 |
| ACTG1 | actin gamma 1 | -0.0495571 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0483917 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0483836 |
| RPS21 | ribosomal protein S21 | -0.0470902 |
| MAP1B | microtubule-associated protein 1B | -0.0467478 |
| RPS8 | ribosomal protein S8 | -0.0456331 |
| FAM162A | family with sequence similarity 162, member A | -0.0448604 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0430568 |
| CPE | carboxypeptidase E | -0.0426123 |
| EGR1 | early growth response 1 | -0.0423705 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0422265 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0419641 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0413093 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0406006 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0401953 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0394569 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0390861 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0388121 |
| PEG10 | paternally expressed 10 | -0.03877 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0387552 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0378398 |
| DSTN | destrin (actin depolymerizing factor) | -0.0375746 |
| RTN4 | reticulon 4 | -0.0366876 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | -0.0365813 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0363944 |
| CADM1 | cell adhesion molecule 1 | -0.03632 |
| ZNF292 | zinc finger protein 292 | -0.0362995 |
| RPL8 | ribosomal protein L8 | -0.0360025 |
| RPL23 | ribosomal protein L23 | -0.0357491 |
| LDHA | lactate dehydrogenase A | -0.0354875 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0353222 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0349072 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0348035 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0344708 |
| S100A9 | S100 calcium binding protein A9 | -0.0340154 |
| SCG2 | secretogranin II | -0.0339216 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0328869 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0326265 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0325688 |
| NCKAP5 | NCK-associated protein 5 | -0.0323567 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.03214 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0320447 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0319477 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.03183 |
| SEPTIN7 | septin 7 | -0.0315564 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0314594 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0312608 |
| PKM | pyruvate kinase, muscle | -0.0305353 |
| RPS19 | ribosomal protein S19 | -0.030392 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.029922 |
| GPHN | gephyrin | -0.0297254 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0295558 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0292098 |
| POTEF | POTE ankyrin domain family, member F | -0.0290649 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.029043 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0289234 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.028753 |
| B2M | beta-2-microglobulin | -0.0285486 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0280721 |
| RPS27A | ribosomal protein S27a | -0.0279806 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.027914 |
| RPL11 | ribosomal protein L11 | -0.0277349 |
| STMN1 | stathmin 1 | -0.0276802 |
| TUBA1B | tubulin, alpha 1b | -0.0266751 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0266702 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0266253 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0266144 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0261153 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.0259555 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0257953 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0257525 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0257406 |
| RPL31 | ribosomal protein L31 | -0.0255043 |
| RPS3 | ribosomal protein S3 | -0.0253826 |
| RPS25 | ribosomal protein S25 | -0.0252584 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.025177 |
| RPLP0 | ribosomal protein, large, P0 | -0.0249323 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.024871 |
| CHGB | chromogranin B | -0.0246429 |
| RPL7 | ribosomal protein L7 | -0.0245776 |
| ECT2 | epithelial cell transforming 2 | -0.0245195 |
| NUP58 | nucleoporin 58 | -0.0245018 |
| CCDC88A | coiled-coil domain containing 88A | -0.0244431 |
| PFN1 | profilin 1 | -0.0243553 |
| CHGA | chromogranin A | -0.0243347 |
