| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Folic acid perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Folic acid_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.21201 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0956925 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0759859 |
| EFNA5 | ephrin-A5 | 0.0680107 |
| NRXN3 | neurexin 3 | 0.0646583 |
| GLIS3 | GLIS family zinc finger 3 | 0.0627465 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0567794 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0566873 |
| EGFR | epidermal growth factor receptor | 0.0559421 |
| AHNAK | AHNAK nucleoprotein | 0.0544256 |
| GSE1 | Gse1 coiled-coil protein | 0.0542192 |
| SMYD3 | SET and MYND domain containing 3 | 0.0532094 |
| RUNX1 | runt-related transcription factor 1 | 0.0509457 |
| HMGA2 | high mobility group AT-hook 2 | 0.0509332 |
| PRELID2 | PRELI domain containing 2 | 0.0507699 |
| COL5A1 | collagen, type V, alpha 1 | 0.045886 |
| SETBP1 | SET binding protein 1 | 0.0445071 |
| LOXL2 | lysyl oxidase-like 2 | 0.0438337 |
| SMAD3 | SMAD family member 3 | 0.0425785 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0424407 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0422378 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0421989 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0384898 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0374699 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.037311 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0370733 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0356784 |
| FN1 | fibronectin 1 | 0.0353697 |
| IL6ST | interleukin 6 signal transducer | 0.0345666 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0340898 |
| KYNU | kynureninase | 0.0337577 |
| EXOC4 | exocyst complex component 4 | 0.0332881 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0330453 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0324612 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0323566 |
| ATP13A3 | ATPase type 13A3 | 0.0323413 |
| PRICKLE2 | prickle homolog 2 (Drosophila) | 0.0314372 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0310677 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0303805 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0297719 |
| MEF2A | myocyte enhancer factor 2A | 0.0292448 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0291789 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0291019 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0290918 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0287458 |
| TNS3 | tensin 3 | 0.0286793 |
| AUTS2 | autism susceptibility candidate 2 | 0.0286399 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0285176 |
| MAP1B | microtubule-associated protein 1B | 0.0284158 |
| HIP1 | huntingtin interacting protein 1 | 0.0283759 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0282266 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.028018 |
| FAM13A | family with sequence similarity 13, member A | 0.0277469 |
| LOX | lysyl oxidase | 0.0276586 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.027658 |
| HPCAL1 | hippocalcin-like 1 | 0.0275677 |
| USP34 | ubiquitin specific peptidase 34 | 0.0265362 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0263855 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0262606 |
| MSN | moesin | 0.0261229 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0252723 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0251263 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0245809 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0240309 |
| DPYD | dihydropyrimidine dehydrogenase | 0.02377 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0236427 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0236388 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0235965 |
| DNAH11 | dynein, axonemal, heavy chain 11 | 0.0235635 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0235621 |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | 0.0234251 |
| ANO6 | anoctamin 6 | 0.0231265 |
| VEGFC | vascular endothelial growth factor C | 0.0230134 |
| ATXN1 | ataxin 1 | 0.0225879 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0225831 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 0.022309 |
| PDGFC | platelet derived growth factor C | 0.0222244 |
| ACTN1 | actinin, alpha 1 | 0.022101 |
| NF1 | neurofibromin 1 | 0.0219292 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0219009 |
| ASPH | aspartate beta-hydroxylase | 0.021793 |
| DST | dystonin | 0.0214851 |
| FMNL2 | formin-like 2 | 0.0214661 |
| VCL | vinculin | 0.0213771 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0210898 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0210648 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0210523 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0208861 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0208631 |
| CDK14 | cyclin-dependent kinase 14 | 0.020636 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0204245 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0204175 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0203624 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0203569 |
| METTL15 | methyltransferase like 15 | 0.0201167 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0198622 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0195884 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0195677 |
| STK17A | serine/threonine kinase 17a | 0.0195545 |
| NRP1 | neuropilin 1 | 0.0194221 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.211395 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.171782 |
| HLA-B | major histocompatibility complex, class I, B | -0.163909 |
| MT2A | metallothionein 2A | -0.151056 |
| TMSB10 | thymosin beta 10 | -0.150562 |
| B2M | beta-2-microglobulin | -0.14001 |
| FTL | ferritin, light polypeptide | -0.0999697 |
| PTMA | prothymosin, alpha | -0.0988399 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0957223 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0905487 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0821243 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0738304 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0728326 |
| POTEF | POTE ankyrin domain family, member F | -0.0557043 |
| ENO1 | enolase 1, (alpha) | -0.0548683 |
| MT1X | metallothionein 1X | -0.0543342 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0481366 |
| S100A9 | S100 calcium binding protein A9 | -0.0471376 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0462859 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0459944 |
| RPS6 | ribosomal protein S6 | -0.0453494 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0443335 |
| S100A6 | S100 calcium binding protein A6 | -0.0441536 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.044152 |
| ACTG1 | actin gamma 1 | -0.0441087 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0440762 |
| HLA-C | major histocompatibility complex, class I, C | -0.043793 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0400693 |
| RPS8 | ribosomal protein S8 | -0.0390906 |
| HLA-A | major histocompatibility complex, class I, A | -0.038337 |
| SEPTIN7 | septin 7 | -0.0383031 |
| RPL35A | ribosomal protein L35a | -0.0380146 |
| GNAS | GNAS complex locus | -0.0377558 |
| RPL37A | ribosomal protein L37a | -0.0374279 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0364759 |
| ADM | adrenomedullin | -0.036387 |
| RPL31 | ribosomal protein L31 | -0.0356125 |
| RPL36 | ribosomal protein L36 | -0.0350694 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0349629 |
| GOLGA4 | golgin A4 | -0.0340603 |
| RPLP1 | ribosomal protein, large, P1 | -0.034013 |
| RPL15 | ribosomal protein L15 | -0.0335028 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0334627 |
| LMNA | lamin A/C | -0.0330311 |
| RPL11 | ribosomal protein L11 | -0.0328419 |
| LDHA | lactate dehydrogenase A | -0.0324672 |
| RPLP2 | ribosomal protein, large, P2 | -0.0315183 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0311444 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0306888 |
| S100A10 | S100 calcium binding protein A10 | -0.0297398 |
| RACK1 | receptor for activated C kinase 1 | -0.0296905 |
| RRBP1 | ribosome binding protein 1 | -0.0295724 |
| RPS27A | ribosomal protein S27a | -0.0292381 |
| PKM | pyruvate kinase, muscle | -0.029048 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0283027 |
| RPS14 | ribosomal protein S14 | -0.0279467 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0276653 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0276506 |
| RPL34 | ribosomal protein L34 | -0.027575 |
| PFN1 | profilin 1 | -0.0274492 |
| RPS19 | ribosomal protein S19 | -0.0272137 |
| RPS23 | ribosomal protein S23 | -0.0269835 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0268538 |
| DSTN | destrin (actin depolymerizing factor) | -0.0267494 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0265426 |
| TUBA1B | tubulin, alpha 1b | -0.0262663 |
| RPL12 | ribosomal protein L12 | -0.0255914 |
| RPS12 | ribosomal protein S12 | -0.0251435 |
| ATF4 | activating transcription factor 4 | -0.0246632 |
| UBC | ubiquitin C | -0.0244659 |
| RPL26 | ribosomal protein L26 | -0.0243385 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0241982 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0241421 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.024085 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0240568 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0238297 |
| CALR | calreticulin | -0.0236846 |
| MYADM | myeloid-associated differentiation marker | -0.0235428 |
| RPS25 | ribosomal protein S25 | -0.0234481 |
| RPL19 | ribosomal protein L19 | -0.0233898 |
| RPS13 | ribosomal protein S13 | -0.0233703 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0231391 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0228678 |
| RPL37 | ribosomal protein L37 | -0.0228437 |
| CD63 | CD63 molecule | -0.0227991 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0227763 |
| TMSB4X | thymosin beta 4, X-linked | -0.0227515 |
| SERF2 | small EDRK-rich factor 2 | -0.0226585 |
| RPS21 | ribosomal protein S21 | -0.0225468 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0224735 |
| RPL32 | ribosomal protein L32 | -0.0224034 |
| HM13 | histocompatibility (minor) 13 | -0.0220194 |
| RPLP0 | ribosomal protein, large, P0 | -0.021703 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.021376 |
| PRSS23 | protease, serine, 23 | -0.0213176 |
| CAVIN1 | caveolae associated protein 1 | -0.0212118 |
| CIRSR | corepressor of RBPJ and splicing regulator | -0.021114 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0211128 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0210372 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0210343 |
