| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Folic acid perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Folic acid_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD36 | CD36 molecule (thrombospondin receptor) | 0.2225 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.106017 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.105294 |
| EGFR | epidermal growth factor receptor | 0.104547 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.103854 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0942364 |
| FAT1 | FAT atypical cadherin 1 | 0.0829787 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0785032 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0696048 |
| EZR | ezrin | 0.0687337 |
| RAD51B | RAD51 paralog B | 0.0661316 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0617442 |
| FHIT | fragile histidine triad | 0.0529106 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0522256 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0449436 |
| ZNRF3 | zinc and ring finger 3 | 0.0449316 |
| EXOC4 | exocyst complex component 4 | 0.0443609 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0436242 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.043498 |
| KITLG | KIT ligand | 0.0434384 |
| AXIN2 | axin 2 | 0.0432758 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0431858 |
| FAM3C | family with sequence similarity 3, member C | 0.0404524 |
| EDAR | ectodysplasin A receptor | 0.040343 |
| ATXN1 | ataxin 1 | 0.03922 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0387118 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0385387 |
| GNAT3 | guanine nucleotide binding protein, alpha transducing 3 | 0.038443 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0357854 |
| EVA1C | eva-1 homolog C (C. elegans) | 0.0356291 |
| TMSB10 | thymosin beta 10 | 0.0349459 |
| ATL2 | atlastin GTPase 2 | 0.0338679 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0325556 |
| BCL2L1 | BCL2-like 1 | 0.032416 |
| OXR1 | oxidation resistance 1 | 0.0319727 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0317785 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0316561 |
| GDF15 | growth differentiation factor 15 | 0.0315728 |
| SPATA13 | spermatogenesis associated 13 | 0.0314057 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0311334 |
| ACTN4 | actinin, alpha 4 | 0.0308133 |
| WWOX | WW domain containing oxidoreductase | 0.0306702 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0306468 |
| FOSL1 | FOS-like antigen 1 | 0.029069 |
| NT5DC3 | 5'-nucleotidase domain containing 3 | 0.0288342 |
| TENM3 | teneurin transmembrane protein 3 | 0.0283773 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0279782 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0279434 |
| EPHA2 | EPH receptor A2 | 0.0270346 |
| RPL3 | ribosomal protein L3 | 0.0266069 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0259303 |
| SLC30A10 | solute carrier family 30, member 10 | 0.0250021 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0247952 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0247256 |
| RNF43 | ring finger protein 43 | 0.0246312 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.0244468 |
| IGSF9B | immunoglobulin superfamily, member 9B | 0.0244061 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0242767 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0238534 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0237896 |
| DUSP4 | dual specificity phosphatase 4 | 0.0236199 |
| VMP1 | vacuole membrane protein 1 | 0.0235056 |
| PHF14 | PHD finger protein 14 | 0.0233176 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.0230049 |
| MCL1 | myeloid cell leukemia 1 | 0.022832 |
| SMYD3 | SET and MYND domain containing 3 | 0.022335 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0220701 |
| HDAC4 | histone deacetylase 4 | 0.0216864 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0215636 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0207077 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0202397 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0201269 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0201241 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0200113 |
| SERINC5 | serine incorporator 5 | 0.0195723 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.019423 |
| FTL | ferritin, light polypeptide | 0.0194158 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.0194083 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0192336 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.0191807 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.019147 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0188629 |
| GPHN | gephyrin | 0.0187629 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0186606 |
| KLF12 | Kruppel-like factor 12 | 0.0185518 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0185406 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0183416 |
| POTEF | POTE ankyrin domain family, member F | 0.0183076 |
| RANBP9 | RAN binding protein 9 | 0.0182526 |
| RREB1 | ras responsive element binding protein 1 | 0.0181817 |
| TXNIP | thioredoxin interacting protein | 0.0181773 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.018143 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.0180244 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0179341 |
| RGS6 | regulator of G-protein signaling 6 | 0.0179076 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0177436 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0172306 |
| EMP1 | epithelial membrane protein 1 | 0.0169167 |
| FHL2 | four and a half LIM domains 2 | 0.0168918 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0165197 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | -0.0994483 |
| AREG | amphiregulin | -0.0915607 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0813366 |
| FERMT1 | fermitin family member 1 | -0.0808703 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0743837 |
| RPS2 | ribosomal protein S2 | -0.0722592 |
| PTMA | prothymosin, alpha | -0.0704357 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0701728 |
| LAMB3 | laminin, beta 3 | -0.0691806 |
| GOLGA4 | golgin A4 | -0.0679922 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0656757 |
| IER3 | immediate early response 3 | -0.0646959 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0597825 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0568132 |
| RPS6 | ribosomal protein S6 | -0.0555716 |
| LDHA | lactate dehydrogenase A | -0.0531441 |
| RPS8 | ribosomal protein S8 | -0.0520032 |
| RPL26 | ribosomal protein L26 | -0.0517066 |
| HDAC2 | histone deacetylase 2 | -0.0487324 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0478528 |
| DSPP | dentin sialophosphoprotein | -0.0453274 |
| RPS24 | ribosomal protein S24 | -0.044842 |
| RBM25 | RNA binding motif protein 25 | -0.0445733 |
| SETD5 | SET domain containing 5 | -0.0431086 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0427928 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.04259 |
| NCOR1 | nuclear receptor corepressor 1 | -0.041738 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0408847 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0404657 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0399242 |
| RPS29 | ribosomal protein S29 | -0.039758 |
| LAMA4 | laminin, alpha 4 | -0.039515 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0387994 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0385903 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0379626 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0377284 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0376534 |
| RPS3 | ribosomal protein S3 | -0.037554 |
| EREG | epiregulin | -0.0370497 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0369583 |
| RPL11 | ribosomal protein L11 | -0.0355715 |
| RPL32 | ribosomal protein L32 | -0.0346124 |
| CD9 | CD9 molecule | -0.0338069 |
| RPL9 | ribosomal protein L9 | -0.0337097 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0334525 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0333476 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0330808 |
| CLTC | clathrin, heavy chain (Hc) | -0.0329009 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0328009 |
| MTAP | methylthioadenosine phosphorylase | -0.0326912 |
| RPS27A | ribosomal protein S27a | -0.0325899 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0322696 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0318042 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0315784 |
| LMO7 | LIM domain 7 | -0.0312514 |
| RPLP2 | ribosomal protein, large, P2 | -0.0311395 |
| GSK3B | glycogen synthase kinase 3 beta | -0.030919 |
| CDC73 | cell division cycle 73 | -0.0308434 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.030811 |
| MKI67 | marker of proliferation Ki-67 | -0.0306454 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0304985 |
| CD44 | CD44 molecule (Indian blood group) | -0.0304242 |
| RPL7 | ribosomal protein L7 | -0.030412 |
| NCKAP1 | NCK-associated protein 1 | -0.0302322 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0299971 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0288088 |
| ANXA1 | annexin A1 | -0.0278838 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0278056 |
| AHNAK | AHNAK nucleoprotein | -0.0277677 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.027618 |
| NUP58 | nucleoporin 58 | -0.0276082 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0275283 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0272862 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.027213 |
| RBM39 | RNA binding motif protein 39 | -0.0270115 |
| UBE3C | ubiquitin protein ligase E3C | -0.0268497 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0266951 |
| SEPTIN7 | septin 7 | -0.0261497 |
| BBX | bobby sox homolog (Drosophila) | -0.0258675 |
| GLG1 | golgi glycoprotein 1 | -0.0258248 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0257802 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0256328 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0255854 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0254086 |
| SPAG9 | sperm associated antigen 9 | -0.0253994 |
| TPR | translocated promoter region, nuclear basket protein | -0.0253692 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0252985 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0252496 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0250271 |
| SET | SET nuclear proto-oncogene | -0.0249242 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0248781 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0247767 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0246702 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0246662 |
| FBXO11 | F-box protein 11 | -0.024554 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0241528 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0240687 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0239636 |
| RLF | rearranged L-myc fusion | -0.0239141 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0238623 |