| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.0710739 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0545673 |
| NFIB | nuclear factor I/B | 0.0520536 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0510791 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0502291 |
| SPPL3 | signal peptide peptidase like 3 | 0.0497278 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0439139 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0425092 |
| FMNL2 | formin-like 2 | 0.0383737 |
| FAM13A | family with sequence similarity 13, member A | 0.037558 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0373238 |
| FN1 | fibronectin 1 | 0.0367926 |
| NFIA | nuclear factor I/A | 0.0348022 |
| QKI | QKI, KH domain containing, RNA binding | 0.0346101 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0337597 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0336547 |
| SETD5 | SET domain containing 5 | 0.0331587 |
| RNF145 | ring finger protein 145 | 0.0330508 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0323489 |
| PRELID2 | PRELI domain containing 2 | 0.0311897 |
| PALLD | palladin, cytoskeletal associated protein | 0.0305825 |
| EFNA5 | ephrin-A5 | 0.0297621 |
| SFTPA2 | surfactant protein A2 | 0.0293161 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.0288045 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0287659 |
| HELZ | helicase with zinc finger | 0.0286497 |
| DST | dystonin | 0.027819 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0273368 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0273358 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0270486 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0269112 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0267889 |
| SMAP1 | small ArfGAP 1 | 0.0267427 |
| SMYD3 | SET and MYND domain containing 3 | 0.0267147 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0266636 |
| MEOX2 | mesenchyme homeobox 2 | 0.0263578 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0258291 |
| GPC6 | glypican 6 | 0.0257349 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0251198 |
| PDS5B | PDS5 cohesin associated factor B | 0.0249733 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0248793 |
| METTL15 | methyltransferase like 15 | 0.0248687 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0247791 |
| RPS3 | ribosomal protein S3 | 0.024679 |
| TMF1 | TATA element modulatory factor 1 | 0.0246036 |
| ASPH | aspartate beta-hydroxylase | 0.0245968 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0243304 |
| MYO1B | myosin IB | 0.0242556 |
| ATXN1 | ataxin 1 | 0.0240957 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0240547 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0238474 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0237663 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0237225 |
| ZNF608 | zinc finger protein 608 | 0.023573 |
| ATOSA | atos homolog A | 0.0234337 |
| SMAD3 | SMAD family member 3 | 0.0230811 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0229012 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0225487 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0225481 |
| CCNG2 | cyclin G2 | 0.0224675 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0224394 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.0224037 |
| TPD52 | tumor protein D52 | 0.0223399 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0221079 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.021929 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0218146 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0215372 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0215134 |
| B2M | beta-2-microglobulin | 0.0214457 |
| RHOA | ras homolog family member A | 0.0213264 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0211609 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0211484 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0211187 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0210487 |
| YBX3 | Y box binding protein 3 | 0.0210365 |
| GPHN | gephyrin | 0.0209898 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0206992 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0206743 |
| RYBP | RING1 and YY1 binding protein | 0.0205739 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0201956 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0200888 |
| RAD51B | RAD51 paralog B | 0.0200496 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0199478 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0199011 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0198592 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0198349 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0198074 |
| ADAR | adenosine deaminase, RNA-specific | 0.0197614 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0197448 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.019712 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0196785 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0196717 |
| DENND4A | DENN/MADD domain containing 4A | 0.0195825 |
| TFG | TRK-fused gene | 0.0195786 |
| IPMK | inositol polyphosphate multikinase | 0.0195338 |
| NUCB2 | nucleobindin 2 | 0.0194194 |
| SECISBP2L | SECIS binding protein 2-like | 0.0194139 |
| CD164 | CD164 molecule, sialomucin | 0.0193495 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0193079 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0192818 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.121692 |
| PEG10 | paternally expressed 10 | -0.106946 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0895335 |
| MEST | mesoderm specific transcript | -0.0769999 |
| RANBP17 | RAN binding protein 17 | -0.0731904 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0694709 |
| MGP | matrix Gla protein | -0.06738 |
| HMGA2 | high mobility group AT-hook 2 | -0.0648332 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.061214 |
| CENPF | centromere protein F, 350/400kDa | -0.0611671 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0580298 |
| MKI67 | marker of proliferation Ki-67 | -0.0577721 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0525209 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0487524 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.046847 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0466629 |
| RPS2 | ribosomal protein S2 | -0.0450915 |
| SEPTIN11 | septin 11 | -0.0446166 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0442535 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0439834 |
| HMGB2 | high mobility group box 2 | -0.0429646 |
| COL1A2 | collagen, type I, alpha 2 | -0.0404841 |
| PDE10A | phosphodiesterase 10A | -0.0393887 |
| RPS6 | ribosomal protein S6 | -0.039014 |
| MATR3 | matrin 3 | -0.0388219 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0383255 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0379543 |
| RBM25 | RNA binding motif protein 25 | -0.0373618 |
| RPS24 | ribosomal protein S24 | -0.0372259 |
| SET | SET nuclear proto-oncogene | -0.0363831 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0361645 |
| RPLP0 | ribosomal protein, large, P0 | -0.0350661 |
| NBEA | neurobeachin | -0.0349986 |
| TMSB4X | thymosin beta 4, X-linked | -0.0347209 |
| KIF11 | kinesin family member 11 | -0.0347135 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0345316 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0344525 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0342452 |
| RPL35A | ribosomal protein L35a | -0.0341787 |
| MT2A | metallothionein 2A | -0.0336936 |
| JMJD1C | jumonji domain containing 1C | -0.0333908 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0333661 |
| ERBIN | erbb2 interacting protein | -0.0333532 |
| TPX2 | TPX2, microtubule-associated | -0.0326875 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0325874 |
| DIAPH3 | diaphanous-related formin 3 | -0.0325697 |
| LDHA | lactate dehydrogenase A | -0.0323388 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0319283 |
| TULP4 | tubby like protein 4 | -0.0315826 |
| TCF12 | transcription factor 12 | -0.0314684 |
| IPO7 | importin 7 | -0.0314564 |
| BUB3 | BUB3 mitotic checkpoint protein | -0.0314479 |
| RPL37 | ribosomal protein L37 | -0.0314232 |
| TBCA | tubulin folding cofactor A | -0.0312813 |
| IER3 | immediate early response 3 | -0.0312693 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0309507 |
| MAP1B | microtubule-associated protein 1B | -0.0309357 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0308264 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.030525 |
| HMGA1 | high mobility group AT-hook 1 | -0.0302937 |
| FUS | FUS RNA binding protein | -0.0301854 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0298304 |
| RPL31 | ribosomal protein L31 | -0.0297112 |
| DOCK1 | dedicator of cytokinesis 1 | -0.029645 |
| RPL38 | ribosomal protein L38 | -0.0295486 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | -0.0295289 |
| FBXO11 | F-box protein 11 | -0.0294232 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0293525 |
| TJP1 | tight junction protein 1 | -0.0293401 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0289549 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0289397 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0288103 |
| E2F3 | E2F transcription factor 3 | -0.0283868 |
| KAZN | kazrin, periplakin interacting protein | -0.0283664 |
| REEP3 | receptor accessory protein 3 | -0.0277939 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0275403 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0274171 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0271141 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0269044 |
| RPS8 | ribosomal protein S8 | -0.0268735 |
| AFF4 | AF4/FMR2 family, member 4 | -0.026794 |
| PKP4 | plakophilin 4 | -0.0267135 |
| RSU1 | Ras suppressor protein 1 | -0.0267106 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0266446 |
| ZFHX3 | zinc finger homeobox 3 | -0.0264817 |
| RPL26 | ribosomal protein L26 | -0.0262772 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.026271 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0261258 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0260576 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0257576 |
| CAPRIN1 | cell cycle associated protein 1 | -0.0256991 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0255222 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0255113 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.02515 |
| ARHGAP11A | Rho GTPase activating protein 11A | -0.0247975 |
| BCOR | BCL6 corepressor | -0.0247313 |
| NAV2 | neuron navigator 2 | -0.0247162 |
| CENPP | centromere protein P | -0.0242737 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.024118 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0239412 |
