| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0613099 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0441548 |
| FAM13A | family with sequence similarity 13, member A | 0.0404159 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.034237 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0334119 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0331655 |
| ZNF292 | zinc finger protein 292 | 0.03282 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0310224 |
| ITGA6 | integrin, alpha 6 | 0.0303888 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0283908 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.028131 |
| RPS2 | ribosomal protein S2 | 0.0257595 |
| SLMAP | sarcolemma associated protein | 0.0256147 |
| NEK7 | NIMA-related kinase 7 | 0.0254013 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0249773 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0242958 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0230294 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0227623 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0225293 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0219602 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.021644 |
| ANLN | anillin, actin binding protein | 0.0214888 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0214743 |
| NPTN | neuroplastin | 0.02117 |
| NCKAP1 | NCK-associated protein 1 | 0.0205932 |
| OGA | O-GlcNAcase | 0.0198108 |
| HPCAL1 | hippocalcin-like 1 | 0.0196492 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0196451 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0193507 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0193287 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0193202 |
| PTMA | prothymosin, alpha | 0.018865 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0186056 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0178565 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0178011 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0176332 |
| RYK | receptor-like tyrosine kinase | 0.0172932 |
| ARRDC3 | arrestin domain containing 3 | 0.0167716 |
| ZNF706 | zinc finger protein 706 | 0.0166031 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0164551 |
| RNF145 | ring finger protein 145 | 0.0163268 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0157739 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0154582 |
| AFDN | afadin, adherens junction formation factor | 0.0153058 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0147621 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0144652 |
| TPD52 | tumor protein D52 | 0.0142929 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0142856 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0142303 |
| YAP1 | Yes-associated protein 1 | 0.0141553 |
| RNF149 | ring finger protein 149 | 0.0138507 |
| MKI67 | marker of proliferation Ki-67 | 0.0137762 |
| EFNA5 | ephrin-A5 | 0.0137355 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0136547 |
| ZFR | zinc finger RNA binding protein | 0.0135563 |
| TJP2 | tight junction protein 2 | 0.0133792 |
| ABHD17C | abhydrolase domain containing 17C | 0.0133022 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0132585 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.013222 |
| SERTAD2 | SERTA domain containing 2 | 0.0130508 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0130324 |
| RPS7 | ribosomal protein S7 | 0.012959 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0128461 |
| RREB1 | ras responsive element binding protein 1 | 0.012801 |
| FAM107B | family with sequence similarity 107, member B | 0.0127073 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.012667 |
| SPOPL | speckle-type POZ protein-like | 0.0123502 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0122987 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0122612 |
| USP3 | ubiquitin specific peptidase 3 | 0.0121334 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0120636 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0119565 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0119279 |
| EXOC1 | exocyst complex component 1 | 0.0119097 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0118871 |
| PRELID2 | PRELI domain containing 2 | 0.011852 |
| CAPRIN2 | caprin family member 2 | 0.0116622 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0116044 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.011602 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0113732 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0113431 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0111761 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0110414 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.010717 |
| TMEM65 | transmembrane protein 65 | 0.0106784 |
| FA2H | fatty acid 2-hydroxylase | 0.0106639 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0106527 |
| PHF21A | PHD finger protein 21A | 0.0106513 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.010628 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0106233 |
| OSBPL1A | oxysterol binding protein-like 1A | 0.0105728 |
| CENPF | centromere protein F, 350/400kDa | 0.0105665 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0105113 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0104936 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0104743 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0104731 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.0103854 |
| MNMIP1 | manchette microtubule inner protein 1 | 0.010327 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0101963 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0101809 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.245196 |
| UBC | ubiquitin C | -0.189827 |
| TXNRD1 | thioredoxin reductase 1 | -0.149503 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.148865 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.145997 |
| LAMB3 | laminin, beta 3 | -0.144145 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.14045 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.134639 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.10706 |
| HMGA1 | high mobility group AT-hook 1 | -0.105222 |
| EGFR | epidermal growth factor receptor | -0.103946 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.101858 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0964694 |
| EZR | ezrin | -0.0964117 |
| VIM | vimentin | -0.0910427 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0884801 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0863506 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0852293 |
| EGR1 | early growth response 1 | -0.084455 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0811968 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0794871 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.077809 |
| LMO7 | LIM domain 7 | -0.0756927 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0732575 |
| KLK10 | kallikrein-related peptidase 10 | -0.0720327 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0711626 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0705213 |
| TRRAP | transformation/transcription domain-associated protein | -0.0698376 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0684549 |
| TXNIP | thioredoxin interacting protein | -0.0683226 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0668094 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0656679 |
| MXD1 | MAX dimerization protein 1 | -0.0640821 |
| AHNAK | AHNAK nucleoprotein | -0.0638745 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0619539 |
| MCL1 | myeloid cell leukemia 1 | -0.0612539 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.060522 |
| LDHA | lactate dehydrogenase A | -0.0600881 |
| LAMA4 | laminin, alpha 4 | -0.0580146 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0575649 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0573884 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0568751 |
| ARF4 | ADP-ribosylation factor 4 | -0.0564309 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.055776 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0555708 |
| RIOK3 | RIO kinase 3 | -0.0550403 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0546029 |
| CALU | calumenin | -0.0544398 |
| FBXO11 | F-box protein 11 | -0.0541355 |
| RASAL2 | RAS protein activator like 2 | -0.0539768 |
| TPM4 | tropomyosin 4 | -0.0535645 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0535099 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0532827 |
| FTL | ferritin, light polypeptide | -0.052444 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0520943 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0499317 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0498637 |
| PARD3 | par-3 family cell polarity regulator | -0.0492493 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0485086 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.04794 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0476959 |
| HDLBP | high density lipoprotein binding protein | -0.0474268 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0470299 |
| LAMC2 | laminin, gamma 2 | -0.0461549 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0458094 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0454662 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0454197 |
| DIAPH1 | diaphanous-related formin 1 | -0.0450364 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0449725 |
| GOLGB1 | golgin B1 | -0.0447873 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0439806 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0435008 |
| RRBP1 | ribosome binding protein 1 | -0.0432177 |
| CLMP | CXADR-like membrane protein | -0.0431348 |
| ACTN4 | actinin, alpha 4 | -0.0426381 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0421284 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0420222 |
| TJP1 | tight junction protein 1 | -0.0415067 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0410053 |
| PCBP2 | poly(rC) binding protein 2 | -0.040826 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0408229 |
| OSMR | oncostatin M receptor | -0.0405806 |
| TAOK3 | TAO kinase 3 | -0.040512 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0401972 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0399094 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0394618 |
| OXSR1 | oxidative stress responsive 1 | -0.039361 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0392709 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0388257 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0387158 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0384951 |
| MORF4L2 | mortality factor 4 like 2 | -0.0378299 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0372338 |
| S100A11 | S100 calcium binding protein A11 | -0.0369908 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0367657 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0363107 |
| B2M | beta-2-microglobulin | -0.0362706 |
| PMM2 | phosphomannomutase 2 | -0.0360227 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0357369 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0357117 |
