| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0736703 |
| NGLY1 | N-glycanase 1 | 0.0585041 |
| ZNF292 | zinc finger protein 292 | 0.0495173 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0475752 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0454594 |
| ARFGEF3 | ARFGEF family member 3 | 0.0438016 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0410012 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0383003 |
| ATRN | attractin | 0.037142 |
| H1-4 | H1.4 linker histone, cluster member | 0.0359445 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0357805 |
| NEBL | nebulette | 0.0347697 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0343939 |
| YEATS2 | YEATS domain containing 2 | 0.033774 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.03361 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.033315 |
| RPS2 | ribosomal protein S2 | 0.0331865 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0324642 |
| OGA | O-GlcNAcase | 0.0323407 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0319158 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0316025 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0315934 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0314656 |
| NCKAP1 | NCK-associated protein 1 | 0.0312608 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0307375 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0298933 |
| ATP11A | ATPase, class VI, type 11A | 0.0291449 |
| HELZ | helicase with zinc finger | 0.0287532 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0287141 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0284635 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0282347 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0281258 |
| PUS7 | pseudouridylate synthase 7 (putative) | 0.0278821 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0272019 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0265163 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0264055 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0263094 |
| FAM13A | family with sequence similarity 13, member A | 0.0261527 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0258131 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0254783 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0253959 |
| FMNL2 | formin-like 2 | 0.0252667 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0251511 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0243282 |
| RPS3A | ribosomal protein S3A | 0.0243121 |
| CDC73 | cell division cycle 73 | 0.0242953 |
| TPD52 | tumor protein D52 | 0.0242544 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0241355 |
| KIF13A | kinesin family member 13A | 0.0241204 |
| CEP95 | centrosomal protein 95kDa | 0.0238944 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0238853 |
| RPL4 | ribosomal protein L4 | 0.0235762 |
| CEP170 | centrosomal protein 170kDa | 0.0235536 |
| KIAA1958 | KIAA1958 | 0.0233364 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0232328 |
| POU2F1 | POU class 2 homeobox 1 | 0.0228827 |
| RPL6 | ribosomal protein L6 | 0.0224577 |
| PCNX1 | pecanex 1 | 0.0224268 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.022355 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0223014 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0222653 |
| USP3 | ubiquitin specific peptidase 3 | 0.0222247 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0219959 |
| SBF2 | SET binding factor 2 | 0.0216938 |
| ZNF544 | zinc finger protein 544 | 0.0216562 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0216226 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0216165 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0214927 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0214326 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0214017 |
| C1ORF21 | chromosome 1 open reading frame 21 | 0.0211603 |
| TRIT1 | tRNA isopentenyltransferase 1 | 0.021099 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) | 0.0210818 |
| RYK | receptor-like tyrosine kinase | 0.0210594 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.0209504 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0207157 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0206754 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0206691 |
| RPL3 | ribosomal protein L3 | 0.0206188 |
| RBM33 | RNA binding motif protein 33 | 0.0205298 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0205066 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0204713 |
| DDHD1 | DDHD domain containing 1 | 0.0198973 |
| SMAP1 | small ArfGAP 1 | 0.0197393 |
| NUP153 | nucleoporin 153kDa | 0.0197109 |
| PTCH1 | patched 1 | 0.0196145 |
| NFIA | nuclear factor I/A | 0.0192872 |
| PDE8A | phosphodiesterase 8A | 0.0192554 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0192326 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0192052 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.0191653 |
| STRBP | spermatid perinuclear RNA binding protein | 0.0191483 |
| NDC1 | NDC1 transmembrane nucleoporin | 0.0190738 |
| ZNF33A | zinc finger protein 33A | 0.0188729 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.018842 |
| PRTG | protogenin | 0.0186114 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0185907 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0183931 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0182835 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0182744 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.175037 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.161667 |
| RAD51B | RAD51 paralog B | -0.151847 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.151727 |
| TMSB10 | thymosin beta 10 | -0.110961 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.108096 |
| NPAS3 | neuronal PAS domain protein 3 | -0.100831 |
| LDHA | lactate dehydrogenase A | -0.0896444 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0886683 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0835493 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0828634 |
| EGR1 | early growth response 1 | -0.082069 |
| RPL35A | ribosomal protein L35a | -0.0718116 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0714513 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0707088 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0655898 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.065298 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0632221 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0617408 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0595098 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0591647 |
| RPS6 | ribosomal protein S6 | -0.0586939 |
| RPL23 | ribosomal protein L23 | -0.0582789 |
| PFN1 | profilin 1 | -0.0578489 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0571578 |
| VIM | vimentin | -0.0552521 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0548626 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0534822 |
| RPLP1 | ribosomal protein, large, P1 | -0.0528839 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0508978 |
| COL5A2 | collagen, type V, alpha 2 | -0.050183 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0498993 |
| RPS8 | ribosomal protein S8 | -0.0482804 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0453536 |
| HMGA1 | high mobility group AT-hook 1 | -0.0452337 |
| FTL | ferritin, light polypeptide | -0.0445997 |
| RPL28 | ribosomal protein L28 | -0.0437002 |
| RPL31 | ribosomal protein L31 | -0.0436101 |
| RBM25 | RNA binding motif protein 25 | -0.0435653 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0433311 |
| MT2A | metallothionein 2A | -0.0431346 |
| RPS19 | ribosomal protein S19 | -0.0421866 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0418947 |
| BNC2 | basonuclin 2 | -0.0408754 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0408114 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0402204 |
| RPS13 | ribosomal protein S13 | -0.0400569 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0399988 |
| RPS21 | ribosomal protein S21 | -0.0398731 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0397809 |
| RPL11 | ribosomal protein L11 | -0.0397343 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0394417 |
| RPS4X | ribosomal protein S4, X-linked | -0.0388142 |
| TXNRD1 | thioredoxin reductase 1 | -0.0385916 |
| BPTF | bromodomain PHD finger transcription factor | -0.0383589 |
| MLIP | muscular LMNA-interacting protein | -0.0383468 |
| RPLP2 | ribosomal protein, large, P2 | -0.0380909 |
| TOX | thymocyte selection-associated high mobility group box | -0.0367652 |
| PKM | pyruvate kinase, muscle | -0.0365896 |
| SHROOM3 | shroom family member 3 | -0.0365041 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0364875 |
| HMGB1 | high mobility group box 1 | -0.036428 |
| ACTG1 | actin gamma 1 | -0.0363648 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0362774 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0359387 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0359129 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0355319 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | -0.0355048 |
| RIGI | RNA sensor RIG-I | -0.0350328 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0349772 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0348538 |
| TENM3 | teneurin transmembrane protein 3 | -0.0343587 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0342261 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0341347 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.03412 |
| TUBB4B | tubulin, beta 4B class IVb | -0.033844 |
| TUBA1B | tubulin, alpha 1b | -0.0334636 |
| MAP1B | microtubule-associated protein 1B | -0.0332617 |
| SALL4 | spalt-like transcription factor 4 | -0.0330995 |
| MAGEA4 | melanoma antigen family A4 | -0.0328894 |
| CDH18 | cadherin 18, type 2 | -0.0327583 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0325074 |
| RPL38 | ribosomal protein L38 | -0.0321644 |
| YBX1 | Y box binding protein 1 | -0.0321279 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0319081 |
| RPL5 | ribosomal protein L5 | -0.0318188 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0317708 |
| ENO1 | enolase 1, (alpha) | -0.0316008 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0309438 |
| FBXO11 | F-box protein 11 | -0.0308362 |
| TPI1 | triosephosphate isomerase 1 | -0.0304646 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0304047 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0303985 |
| RPLP0 | ribosomal protein, large, P0 | -0.0303819 |
| NRG1 | neuregulin 1 | -0.0298698 |
| RPS11 | ribosomal protein S11 | -0.0295643 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.0293786 |
| RPL13A | ribosomal protein L13a | -0.0292922 |
| DEK | DEK proto-oncogene | -0.0292878 |
| TUBB | tubulin, beta class I | -0.0291583 |
