| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.103257 |
| B2M | beta-2-microglobulin | 0.0783123 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0629364 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.05744 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0488351 |
| TGM2 | transglutaminase 2 | 0.0478487 |
| CCNY | cyclin Y | 0.0475508 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0413975 |
| NDRG1 | N-myc downstream regulated 1 | 0.0411587 |
| FOSL1 | FOS-like antigen 1 | 0.0403531 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0382336 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0357651 |
| FLNB | filamin B, beta | 0.0350964 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0344294 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0316528 |
| MEF2A | myocyte enhancer factor 2A | 0.0277057 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0273589 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0273121 |
| HPCAL1 | hippocalcin-like 1 | 0.0260419 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0247193 |
| SRP54 | signal recognition particle 54kDa | 0.0246489 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0239814 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0234124 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0222919 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0220703 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0219363 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0213379 |
| RCOR1 | REST corepressor 1 | 0.0212588 |
| RAB8B | RAB8B, member RAS oncogene family | 0.021067 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0209156 |
| MCL1 | myeloid cell leukemia 1 | 0.0209123 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0206207 |
| MSN | moesin | 0.0202534 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0202281 |
| SACK1B | scaffolding CK1 anchoring protein B | 0.0199525 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0192492 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0186886 |
| AGRN | agrin | 0.0183067 |
| RNF149 | ring finger protein 149 | 0.0182129 |
| CCNL1 | cyclin L1 | 0.0180939 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.0178742 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0174443 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.017415 |
| PDGFB | platelet-derived growth factor beta polypeptide | 0.0173562 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.017235 |
| TPM3 | tropomyosin 3 | 0.0172307 |
| ZNF395 | zinc finger protein 395 | 0.016961 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0169528 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0168555 |
| RNASET2 | ribonuclease T2 | 0.0167055 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0166957 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | 0.016526 |
| VEGFA | vascular endothelial growth factor A | 0.0164528 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0161741 |
| NCKAP1 | NCK-associated protein 1 | 0.0160224 |
| SEPTIN9 | septin 9 | 0.0160072 |
| RNF24 | ring finger protein 24 | 0.0159505 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0159219 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0157364 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0157206 |
| CTTN | cortactin | 0.01572 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0155685 |
| HELZ | helicase with zinc finger | 0.0155626 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0155181 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0154745 |
| HDGF | hepatoma-derived growth factor | 0.0153719 |
| DTNA | dystrobrevin, alpha | 0.0153311 |
| APOL1 | apolipoprotein L, 1 | 0.0153078 |
| HLA-A | major histocompatibility complex, class I, A | 0.0152889 |
| PRELID2 | PRELI domain containing 2 | 0.0150935 |
| CCNG2 | cyclin G2 | 0.015054 |
| AXL | AXL receptor tyrosine kinase | 0.0150307 |
| ATXN1 | ataxin 1 | 0.0149409 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0147483 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0144834 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.01447 |
| SETD5 | SET domain containing 5 | 0.0142049 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0141136 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | 0.0139945 |
| SMAD3 | SMAD family member 3 | 0.0139769 |
| MPZL2 | myelin protein zero-like 2 | 0.0138842 |
| PROSER2 | proline and serine rich 2 | 0.0138243 |
| H1-4 | H1.4 linker histone, cluster member | 0.0135423 |
| RAI1 | retinoic acid induced 1 | 0.0135065 |
| TXNIP | thioredoxin interacting protein | 0.0134344 |
| C3 | complement component 3 | 0.0134159 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0134128 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0132497 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0131657 |
| TMEM165 | transmembrane protein 165 | 0.0131285 |
| FAM117B | family with sequence similarity 117, member B | 0.0130495 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0129596 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0127983 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) | 0.0125106 |
| INSIG2 | insulin induced gene 2 | 0.0124083 |
| PLAT | plasminogen activator, tissue | 0.0123653 |
| ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | 0.0123583 |
| BCL2L1 | BCL2-like 1 | 0.0123049 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0122871 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0122822 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.242614 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.169098 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.128132 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.123331 |
| LOC112694756 | uncharaterized LOC112694756 | -0.122296 |
| UBC | ubiquitin C | -0.120292 |
| RPL23 | ribosomal protein L23 | -0.0908975 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0875747 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0833024 |
| KRT19 | keratin 19, type I | -0.0818106 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0701715 |
| RPLP1 | ribosomal protein, large, P1 | -0.0667766 |
| TMSB4X | thymosin beta 4, X-linked | -0.0655525 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0628048 |
| AHNAK | AHNAK nucleoprotein | -0.062047 |
| HMGA1 | high mobility group AT-hook 1 | -0.0608325 |
| PKM | pyruvate kinase, muscle | -0.0593283 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0590833 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.058694 |
| LDHA | lactate dehydrogenase A | -0.0586543 |
| RPL35A | ribosomal protein L35a | -0.0585234 |
| APP | amyloid beta (A4) precursor protein | -0.0577861 |
| ENO1 | enolase 1, (alpha) | -0.0571945 |
| VIM | vimentin | -0.0535998 |
| MT1X | metallothionein 1X | -0.0532999 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0523157 |
| ASPH | aspartate beta-hydroxylase | -0.0503796 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0503214 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0502719 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0480943 |
| MMP7 | matrix metallopeptidase 7 | -0.0479905 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0464073 |
| SPAG9 | sperm associated antigen 9 | -0.0459272 |
| EZR | ezrin | -0.0453257 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0452484 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0451727 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0444731 |
| CANX | calnexin | -0.0439426 |
| RBM39 | RNA binding motif protein 39 | -0.0435672 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0429623 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0423046 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.04047 |
| EFNA5 | ephrin-A5 | -0.0402494 |
| SP100 | SP100 nuclear antigen | -0.0401921 |
| HLA-B | major histocompatibility complex, class I, B | -0.0399752 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0398529 |
| YBX1 | Y box binding protein 1 | -0.0397656 |
| MYO1E | myosin IE | -0.0397102 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.039667 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0390416 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0386464 |
| RPS24 | ribosomal protein S24 | -0.0384384 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0383856 |
| LMO7 | LIM domain 7 | -0.0381473 |
| LASP1 | LIM and SH3 protein 1 | -0.0378343 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0376909 |
| RNF213 | ring finger protein 213 | -0.0367733 |
| S100A6 | S100 calcium binding protein A6 | -0.0363233 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0361918 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0359352 |
| FTL | ferritin, light polypeptide | -0.035811 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0355831 |
| RPLP0 | ribosomal protein, large, P0 | -0.0354646 |
| TPM1 | tropomyosin 1 (alpha) | -0.0351967 |
| TJP1 | tight junction protein 1 | -0.0346884 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0343077 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0338733 |
| RPL34 | ribosomal protein L34 | -0.0336599 |
| OSMR | oncostatin M receptor | -0.0335769 |
| ARF1 | ADP-ribosylation factor 1 | -0.0333932 |
| CD2AP | CD2-associated protein | -0.0329144 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0327077 |
| MYOF | myoferlin | -0.0327034 |
| MORF4L2 | mortality factor 4 like 2 | -0.0326967 |
| ANXA2 | annexin A2 | -0.0323185 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0322846 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0320761 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0320041 |
| BICC1 | BicC family RNA binding protein 1 | -0.0314607 |
| PLAU | plasminogen activator, urokinase | -0.03133 |
| AFF4 | AF4/FMR2 family, member 4 | -0.031104 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0309825 |
| RPL31 | ribosomal protein L31 | -0.0308888 |
| LAMC2 | laminin, gamma 2 | -0.0306129 |
| SDC4 | syndecan 4 | -0.0305663 |
| RPS27A | ribosomal protein S27a | -0.0302706 |
| EGR1 | early growth response 1 | -0.0300725 |
| RRBP1 | ribosome binding protein 1 | -0.0299361 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0298933 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0296815 |
| JUN | jun proto-oncogene | -0.0294731 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0293061 |
| APOL2 | apolipoprotein L, 2 | -0.028858 |
| MT2A | metallothionein 2A | -0.0288331 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0285789 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0281408 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0279703 |
| PHF3 | PHD finger protein 3 | -0.027825 |
| RPL19 | ribosomal protein L19 | -0.027818 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0277795 |
