| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0618921 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0557526 |
| RNF149 | ring finger protein 149 | 0.0545212 |
| PTMA | prothymosin, alpha | 0.0514817 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0510048 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0492144 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0450592 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0404613 |
| RPS6 | ribosomal protein S6 | 0.0401705 |
| TXNIP | thioredoxin interacting protein | 0.0395245 |
| B2M | beta-2-microglobulin | 0.0351003 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0344708 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0334533 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0330775 |
| RPL37A | ribosomal protein L37a | 0.0321676 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0309666 |
| RPS8 | ribosomal protein S8 | 0.0305868 |
| RPL26 | ribosomal protein L26 | 0.0299351 |
| FTL | ferritin, light polypeptide | 0.0298385 |
| ENO1 | enolase 1, (alpha) | 0.0297921 |
| RPS3 | ribosomal protein S3 | 0.0296663 |
| RPLP1 | ribosomal protein, large, P1 | 0.0295141 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0279402 |
| RPL34 | ribosomal protein L34 | 0.025336 |
| RPL19 | ribosomal protein L19 | 0.025175 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0244667 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0244661 |
| OGA | O-GlcNAcase | 0.0242312 |
| SBF2 | SET binding factor 2 | 0.0240125 |
| GOLGA4 | golgin A4 | 0.0237573 |
| PFKP | phosphofructokinase, platelet | 0.0230406 |
| PGK1 | phosphoglycerate kinase 1 | 0.0225783 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0222738 |
| LCN2 | lipocalin 2 | 0.0213583 |
| PLSCR2 | phospholipid scramblase 2 | 0.0212331 |
| NDRG1 | N-myc downstream regulated 1 | 0.0210807 |
| RPL35A | ribosomal protein L35a | 0.0209852 |
| DSTN | destrin (actin depolymerizing factor) | 0.0208501 |
| RPL12 | ribosomal protein L12 | 0.0204924 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0202215 |
| RPS12 | ribosomal protein S12 | 0.0201519 |
| RPL37 | ribosomal protein L37 | 0.0200267 |
| RPL9 | ribosomal protein L9 | 0.0197483 |
| RPL31 | ribosomal protein L31 | 0.019553 |
| SFXN1 | sideroflexin 1 | 0.0195171 |
| PDS5B | PDS5 cohesin associated factor B | 0.0191954 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0191475 |
| RPS19 | ribosomal protein S19 | 0.0186728 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0184972 |
| PURA | purine-rich element binding protein A | 0.0184681 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0184129 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0183493 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0182672 |
| PRELID2 | PRELI domain containing 2 | 0.0179853 |
| RPS17 | ribosomal protein S17 | 0.0176431 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0176213 |
| MT2A | metallothionein 2A | 0.0175857 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0172136 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0170262 |
| RPL7A | ribosomal protein L7a | 0.0169308 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0169004 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0166401 |
| USP3 | ubiquitin specific peptidase 3 | 0.016638 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0165349 |
| RPLP0 | ribosomal protein, large, P0 | 0.0165113 |
| RPL18 | ribosomal protein L18 | 0.0164972 |
| PDE8A | phosphodiesterase 8A | 0.0163375 |
| RPL11 | ribosomal protein L11 | 0.016277 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0161134 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.016011 |
| RPL23 | ribosomal protein L23 | 0.0159444 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0158963 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0158067 |
| RPS23 | ribosomal protein S23 | 0.0157824 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0156008 |
| RPS2 | ribosomal protein S2 | 0.015593 |
| USP34 | ubiquitin specific peptidase 34 | 0.0155347 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0154198 |
| RPS27A | ribosomal protein S27a | 0.0153926 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0153225 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0152224 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.015093 |
| RPL4 | ribosomal protein L4 | 0.0150663 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0146704 |
| RNF145 | ring finger protein 145 | 0.014593 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0145925 |
| FANCI | Fanconi anemia, complementation group I | 0.0144968 |
| S100A9 | S100 calcium binding protein A9 | 0.0144542 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0143898 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0142982 |
| CDCP1 | CUB domain containing protein 1 | 0.0142423 |
| RPL35 | ribosomal protein L35 | 0.0142003 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0141632 |
| CDC27 | cell division cycle 27 | 0.0141089 |
| RPS29 | ribosomal protein S29 | 0.0140979 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0140261 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0139894 |
| H2AC6 | H2A clustered histone 6 | 0.0139836 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0139547 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0139249 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.179248 |
| MACC1 | metastasis associated in colon cancer 1 | -0.134315 |
| EGR1 | early growth response 1 | -0.133155 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.1139 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.106847 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0995062 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0920991 |
| RNF213 | ring finger protein 213 | -0.0875464 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0848599 |
| PLSCR1 | phospholipid scramblase 1 | -0.0843587 |
| MYO1E | myosin IE | -0.0812128 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0811184 |
| EZR | ezrin | -0.0810231 |
| ANXA2 | annexin A2 | -0.0749961 |
| MX1 | MX dynamin-like GTPase 1 | -0.0741192 |
| ERBIN | erbb2 interacting protein | -0.0718904 |
| RIGI | RNA sensor RIG-I | -0.070604 |
| SPATA13 | spermatogenesis associated 13 | -0.0691414 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0665684 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0659531 |
| VMP1 | vacuole membrane protein 1 | -0.0643789 |
| SQSTM1 | sequestosome 1 | -0.0625073 |
| ITGA6 | integrin, alpha 6 | -0.059855 |
| JUN | jun proto-oncogene | -0.0578876 |
| VCL | vinculin | -0.0570807 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.055765 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0540544 |
| NCKAP5 | NCK-associated protein 5 | -0.0538099 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0537001 |
| CCNL1 | cyclin L1 | -0.0521347 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0517785 |
| MX2 | MX dynamin-like GTPase 2 | -0.0512791 |
| SP100 | SP100 nuclear antigen | -0.0508472 |
| EPHB2 | EPH receptor B2 | -0.049005 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.047974 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0445744 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0441397 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0440174 |
| EXT1 | exostosin glycosyltransferase 1 | -0.043821 |
| ATP11A | ATPase, class VI, type 11A | -0.0437279 |
| IRF1 | interferon regulatory factor 1 | -0.0433572 |
| TJP1 | tight junction protein 1 | -0.0430278 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0411206 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0409986 |
| STK24 | serine/threonine kinase 24 | -0.0406524 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0402364 |
| LYZ | lysozyme | -0.0400536 |
| TMC5 | transmembrane channel-like 5 | -0.0397032 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0369266 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0369162 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0365912 |
| MECOM | MDS1 and EVI1 complex locus | -0.036324 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0357978 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0357202 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0342261 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0339616 |
| PRKCA | protein kinase C, alpha | -0.0332994 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0331049 |
| FOXP1 | forkhead box P1 | -0.0329589 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0327993 |
| KIAA1217 | KIAA1217 | -0.0322344 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.032192 |
| OCLN | occludin | -0.0319233 |
| MCU | mitochondrial calcium uniporter | -0.0317155 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0312486 |
| RBM47 | RNA binding motif protein 47 | -0.0311895 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0311872 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.031168 |
| RUNX1 | runt-related transcription factor 1 | -0.0310487 |
| USP54 | ubiquitin specific peptidase 54 | -0.0310284 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.030745 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0305166 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0304864 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0304566 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0302332 |
| RBM39 | RNA binding motif protein 39 | -0.0302246 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0301145 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0296202 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0295384 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0294288 |
| INTS6 | integrator complex subunit 6 | -0.0294163 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0291782 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0291652 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0290523 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0289247 |
| EFNB2 | ephrin-B2 | -0.0285431 |
| COPA | coatomer protein complex, subunit alpha | -0.0280164 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0276691 |
| TRIM25 | tripartite motif containing 25 | -0.0276649 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0273593 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0273587 |
| ADIPOR2 | adiponectin receptor 2 | -0.0271734 |
| JAK1 | Janus kinase 1 | -0.0269862 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0267941 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0261376 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.026121 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0258325 |
| SPAG9 | sperm associated antigen 9 | -0.0258026 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0256061 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0254969 |
