| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | 0.0551764 |
| ZNF292 | zinc finger protein 292 | 0.047242 |
| H1-4 | H1.4 linker histone, cluster member | 0.0426943 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0406812 |
| WWOX | WW domain containing oxidoreductase | 0.0388454 |
| NCKAP1 | NCK-associated protein 1 | 0.0387397 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0349038 |
| FTL | ferritin, light polypeptide | 0.0345738 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0338611 |
| RPS12 | ribosomal protein S12 | 0.0314292 |
| OGA | O-GlcNAcase | 0.031118 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0290503 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0271364 |
| B2M | beta-2-microglobulin | 0.0263848 |
| RPL4 | ribosomal protein L4 | 0.0263578 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0256402 |
| RPS8 | ribosomal protein S8 | 0.024722 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0246624 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0233081 |
| CTTN | cortactin | 0.0232595 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0231301 |
| H1-0 | H1.0 linker histone | 0.0230469 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0229162 |
| RPS19 | ribosomal protein S19 | 0.0227135 |
| KLF6 | Kruppel-like factor 6 | 0.0226722 |
| RPS2 | ribosomal protein S2 | 0.0221757 |
| ZFR | zinc finger RNA binding protein | 0.0218744 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0214013 |
| CCNT2 | cyclin T2 | 0.0210693 |
| RPL32 | ribosomal protein L32 | 0.0208165 |
| RPL37A | ribosomal protein L37a | 0.0205469 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0204455 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0203881 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.020104 |
| RPLP2 | ribosomal protein, large, P2 | 0.0199391 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0197807 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.019766 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0196764 |
| RPL26 | ribosomal protein L26 | 0.019529 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0194601 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0192771 |
| DCAF5 | DDB1 and CUL4 associated factor 5 | 0.0190381 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0186394 |
| RPL6 | ribosomal protein L6 | 0.0181924 |
| CCNL1 | cyclin L1 | 0.0181299 |
| RPS29 | ribosomal protein S29 | 0.0180417 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0179035 |
| AFDN | afadin, adherens junction formation factor | 0.0178582 |
| USP3 | ubiquitin specific peptidase 3 | 0.0176065 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0175519 |
| DSG2 | desmoglein 2 | 0.0175156 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0173032 |
| RPL9 | ribosomal protein L9 | 0.0170513 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0168764 |
| RPL27 | ribosomal protein L27 | 0.0168534 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0166527 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | 0.0165193 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0165105 |
| PREPL | prolyl endopeptidase-like | 0.0164381 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0162545 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0161952 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0161894 |
| SETD5 | SET domain containing 5 | 0.0161026 |
| RPS3A | ribosomal protein S3A | 0.0160243 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0158874 |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 | 0.0158025 |
| RPL3 | ribosomal protein L3 | 0.0157454 |
| RPS27A | ribosomal protein S27a | 0.0157375 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0156991 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0156122 |
| CREBRF | CREB3 regulatory factor | 0.0156056 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0156028 |
| GPX4 | glutathione peroxidase 4 | 0.0153146 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0151476 |
| ZNF706 | zinc finger protein 706 | 0.015072 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0149578 |
| SNX9 | sorting nexin 9 | 0.0149397 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.014922 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.014899 |
| SELENOK | selenoprotein K | 0.0148798 |
| RPS7 | ribosomal protein S7 | 0.014732 |
| RPS10 | ribosomal protein S10 | 0.014499 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0144931 |
| MAPK1 | mitogen-activated protein kinase 1 | 0.0144669 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.014412 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.014383 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.014338 |
| UBQLN1 | ubiquilin 1 | 0.0142129 |
| QKI | QKI, KH domain containing, RNA binding | 0.0142129 |
| NEK7 | NIMA-related kinase 7 | 0.0141979 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | 0.0141072 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0141006 |
| RNF24 | ring finger protein 24 | 0.0140377 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0140203 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0140062 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0139734 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.013862 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0137186 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0136851 |
| RPS25 | ribosomal protein S25 | 0.0136767 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHA | lactate dehydrogenase A | -0.145374 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.121975 |
| ASPH | aspartate beta-hydroxylase | -0.120777 |
| NDRG1 | N-myc downstream regulated 1 | -0.112392 |
| HMGA1 | high mobility group AT-hook 1 | -0.0969363 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0947461 |
| POTEF | POTE ankyrin domain family, member F | -0.0941857 |
| PKM | pyruvate kinase, muscle | -0.093928 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0896849 |
| TMSB10 | thymosin beta 10 | -0.0856184 |
| TPM4 | tropomyosin 4 | -0.0844012 |
| EGFR | epidermal growth factor receptor | -0.0843341 |
| PAX8 | paired box 8 | -0.080941 |
| SVIL | supervillin | -0.0807358 |
| CCND1 | cyclin D1 | -0.079608 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0775531 |
| BPTF | bromodomain PHD finger transcription factor | -0.0770653 |
| EGR1 | early growth response 1 | -0.0762806 |
| TXNRD1 | thioredoxin reductase 1 | -0.0752468 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0744902 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0744005 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0734462 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0686317 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0638329 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0625417 |
| MT2A | metallothionein 2A | -0.0623651 |
| ENO1 | enolase 1, (alpha) | -0.0602476 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0595936 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0594573 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0577397 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0544809 |
| HMGA2 | high mobility group AT-hook 2 | -0.054128 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0532093 |
| CD44 | CD44 molecule (Indian blood group) | -0.0509874 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0488276 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0482023 |
| KRT7 | keratin 7, type II | -0.0481023 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0474464 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0458617 |
| FLNB | filamin B, beta | -0.0457554 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0449487 |
| AHNAK | AHNAK nucleoprotein | -0.0445531 |
| VCAN | versican | -0.043798 |
| CANX | calnexin | -0.0437557 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0436243 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0433395 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0421082 |
| ITGB8 | integrin, beta 8 | -0.0415488 |
| ZNF638 | zinc finger protein 638 | -0.0406682 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0406563 |
| ITGA6 | integrin, alpha 6 | -0.0404594 |
| LAMA4 | laminin, alpha 4 | -0.0401849 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0392717 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0389765 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0386127 |
| ANXA3 | annexin A3 | -0.0384408 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0380579 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.037969 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0376957 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0375987 |
| MAP4 | microtubule-associated protein 4 | -0.0375107 |
| ERBIN | erbb2 interacting protein | -0.0373712 |
| KRT19 | keratin 19, type I | -0.03701 |
| TAOK1 | TAO kinase 1 | -0.0370027 |
| ANXA1 | annexin A1 | -0.0363383 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0362996 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0362395 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.03618 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0361668 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0361021 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0359858 |
| MYADM | myeloid-associated differentiation marker | -0.0359342 |
| TNIK | TRAF2 and NCK interacting kinase | -0.035775 |
| VMP1 | vacuole membrane protein 1 | -0.0355152 |
| TMSB4X | thymosin beta 4, X-linked | -0.0349802 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0349451 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0345026 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0344928 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0341256 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0340108 |
| GPR39 | G protein-coupled receptor 39 | -0.0331453 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0328506 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0327538 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0325879 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0325545 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0324605 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0324124 |
| CALR | calreticulin | -0.0321981 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0321736 |
| RAD51B | RAD51 paralog B | -0.0320069 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0316878 |
| CDCP1 | CUB domain containing protein 1 | -0.0315132 |
| CCDC138 | coiled-coil domain containing 138 | -0.0314658 |
| PTK2 | protein tyrosine kinase 2 | -0.0311636 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0310933 |
| TCF12 | transcription factor 12 | -0.0309642 |
| EZR | ezrin | -0.0309536 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0309512 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0308622 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0308504 |
