| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0668923 |
| PTMA | prothymosin, alpha | 0.0641403 |
| FAM13A | family with sequence similarity 13, member A | 0.0635499 |
| B2M | beta-2-microglobulin | 0.0590082 |
| NDRG1 | N-myc downstream regulated 1 | 0.0552224 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0475895 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0395206 |
| RPL21 | ribosomal protein L21 | 0.038399 |
| RPS12 | ribosomal protein S12 | 0.0378542 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0328257 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0305798 |
| RPS3 | ribosomal protein S3 | 0.0281823 |
| CDK19 | cyclin-dependent kinase 19 | 0.0278414 |
| POTEF | POTE ankyrin domain family, member F | 0.0275782 |
| ZNF292 | zinc finger protein 292 | 0.0273214 |
| SETD5 | SET domain containing 5 | 0.0262567 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0262431 |
| RPS2 | ribosomal protein S2 | 0.0260333 |
| RPL37A | ribosomal protein L37a | 0.0259623 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0256398 |
| TMEM165 | transmembrane protein 165 | 0.0240371 |
| CCNY | cyclin Y | 0.0237157 |
| HELZ | helicase with zinc finger | 0.023294 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0229237 |
| GOLGA4 | golgin A4 | 0.0224739 |
| FNIP1 | folliculin interacting protein 1 | 0.0222713 |
| CCNL1 | cyclin L1 | 0.0219128 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0217502 |
| TNS1 | tensin 1 | 0.0210529 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0205416 |
| CREBRF | CREB3 regulatory factor | 0.0205148 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0201142 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0200889 |
| HDGF | hepatoma-derived growth factor | 0.0198983 |
| RPS6 | ribosomal protein S6 | 0.0198493 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0197702 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0197569 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0197413 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0195348 |
| RPL3 | ribosomal protein L3 | 0.0195221 |
| DSTN | destrin (actin depolymerizing factor) | 0.0194194 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0192742 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.019145 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0188557 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0186242 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.018045 |
| VEGFA | vascular endothelial growth factor A | 0.0179447 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0179388 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0177051 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.017335 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0172677 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0171652 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0167878 |
| USP24 | ubiquitin specific peptidase 24 | 0.0165969 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0165664 |
| PFKP | phosphofructokinase, platelet | 0.016489 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0162609 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0162104 |
| VIM | vimentin | 0.0159003 |
| CTTN | cortactin | 0.0158322 |
| TMF1 | TATA element modulatory factor 1 | 0.0157997 |
| RNF145 | ring finger protein 145 | 0.0157149 |
| NCKAP1 | NCK-associated protein 1 | 0.0155985 |
| UBN2 | ubinuclein 2 | 0.0155523 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0155347 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0154097 |
| PNN | pinin, desmosome associated protein | 0.015251 |
| SQLE | squalene epoxidase | 0.0151153 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0148565 |
| KIF16B | kinesin family member 16B | 0.0148353 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0147923 |
| FBXO42 | F-box protein 42 | 0.0146435 |
| PGK1 | phosphoglycerate kinase 1 | 0.0146046 |
| H1-4 | H1.4 linker histone, cluster member | 0.0145001 |
| PTEN | phosphatase and tensin homolog | 0.0144017 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0143682 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0143228 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0142253 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.0141158 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0139912 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.013898 |
| RNF149 | ring finger protein 149 | 0.0138621 |
| RBM26 | RNA binding motif protein 26 | 0.0138336 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0138185 |
| BRD4 | bromodomain containing 4 | 0.0137322 |
| HLA-A | major histocompatibility complex, class I, A | 0.0137138 |
| CEP57 | centrosomal protein 57kDa | 0.0136806 |
| RPLP2 | ribosomal protein, large, P2 | 0.0136682 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | 0.0136632 |
| FAM193A | family with sequence similarity 193, member A | 0.0135178 |
| PGM3 | phosphoglucomutase 3 | 0.0134663 |
| SRP54 | signal recognition particle 54kDa | 0.0134311 |
| RO60 | Ro60, Y RNA binding protein | 0.013379 |
| RPL9 | ribosomal protein L9 | 0.0133025 |
| RPL7A | ribosomal protein L7a | 0.0131937 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.013175 |
| INSIG2 | insulin induced gene 2 | 0.0130128 |
| MKI67 | marker of proliferation Ki-67 | 0.0130065 |
| EREG | epiregulin | 0.012959 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0129354 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.15622 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.138739 |
| EXT1 | exostosin glycosyltransferase 1 | -0.123901 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.121624 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.120049 |
| TJP1 | tight junction protein 1 | -0.116078 |
| ACTN4 | actinin, alpha 4 | -0.102844 |
| LMO7 | LIM domain 7 | -0.102108 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0969256 |
| MYO1E | myosin IE | -0.0857513 |
| AHNAK | AHNAK nucleoprotein | -0.0834293 |
| TMSB10 | thymosin beta 10 | -0.0830149 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0821932 |
| KRT20 | keratin 20, type I | -0.0804437 |
| LOC112694756 | uncharaterized LOC112694756 | -0.079462 |
| SMAD3 | SMAD family member 3 | -0.0788612 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0772361 |
| RPL23 | ribosomal protein L23 | -0.0770499 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0762503 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0738317 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0737628 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0699062 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.068699 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0656103 |
| VCL | vinculin | -0.0640769 |
| ANXA2 | annexin A2 | -0.063009 |
| STK24 | serine/threonine kinase 24 | -0.0622858 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0620558 |
| EZR | ezrin | -0.0601534 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0598981 |
| UBC | ubiquitin C | -0.0595884 |
| HDLBP | high density lipoprotein binding protein | -0.0589877 |
| EGR1 | early growth response 1 | -0.0586985 |
| TRIB1 | tribbles pseudokinase 1 | -0.057838 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0574082 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0572872 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0559072 |
| LDHA | lactate dehydrogenase A | -0.0558079 |
| SQSTM1 | sequestosome 1 | -0.0530887 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.053001 |
| NF1 | neurofibromin 1 | -0.0523734 |
| WWC1 | WW and C2 domain containing 1 | -0.050866 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0491822 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0483098 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0479277 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0473611 |
| RPS24 | ribosomal protein S24 | -0.0470377 |
| ARF1 | ADP-ribosylation factor 1 | -0.0467379 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0463619 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0462372 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0461141 |
| SDCBP | syndecan binding protein (syntenin) | -0.0457956 |
| RTN3 | reticulon 3 | -0.0453417 |
| CANX | calnexin | -0.0443974 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0433788 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0433189 |
| PDZD8 | PDZ domain containing 8 | -0.0428532 |
| RPLP1 | ribosomal protein, large, P1 | -0.0427274 |
| JUN | jun proto-oncogene | -0.0424379 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0424156 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0420376 |
| LAMA4 | laminin, alpha 4 | -0.0417877 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0417832 |
| RHEB | Ras homolog enriched in brain | -0.0417377 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0408612 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0406077 |
| RRBP1 | ribosome binding protein 1 | -0.040346 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0400872 |
| SDC4 | syndecan 4 | -0.0385141 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0382211 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.037482 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0372738 |
| POF1B | premature ovarian failure, 1B | -0.0369144 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0363843 |
| RBM39 | RNA binding motif protein 39 | -0.0362642 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0361694 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0361205 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0360539 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0351225 |
| RPL35A | ribosomal protein L35a | -0.0346887 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0346161 |
| MORF4L2 | mortality factor 4 like 2 | -0.0344115 |
| HMGB1 | high mobility group box 1 | -0.0341186 |
| SGMS2 | sphingomyelin synthase 2 | -0.0339541 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0337177 |
| DST | dystonin | -0.033354 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0329503 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0329379 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.032794 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0325968 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0324737 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0324661 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0324142 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0323829 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0320823 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.032002 |
| TUFT1 | tuftelin 1 | -0.0318135 |
| LASP1 | LIM and SH3 protein 1 | -0.0317579 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0316868 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0315824 |
