| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.1441 |
| B2M | beta-2-microglobulin | 0.134583 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.100975 |
| STC1 | stanniocalcin 1 | 0.0983051 |
| RPS8 | ribosomal protein S8 | 0.0912161 |
| RPS6 | ribosomal protein S6 | 0.0889889 |
| ENO1 | enolase 1, (alpha) | 0.0847301 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0839858 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.076463 |
| MT2A | metallothionein 2A | 0.0757534 |
| CLU | clusterin | 0.074419 |
| MEF2A | myocyte enhancer factor 2A | 0.0730592 |
| PGK1 | phosphoglycerate kinase 1 | 0.0697461 |
| RPS12 | ribosomal protein S12 | 0.0585585 |
| GOLGA4 | golgin A4 | 0.0579698 |
| RPS3 | ribosomal protein S3 | 0.0560563 |
| RPLP2 | ribosomal protein, large, P2 | 0.0550317 |
| S100A10 | S100 calcium binding protein A10 | 0.0540547 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0521279 |
| RPL11 | ribosomal protein L11 | 0.0517284 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0511203 |
| ITGA6 | integrin, alpha 6 | 0.050819 |
| RPS19 | ribosomal protein S19 | 0.050789 |
| NDRG1 | N-myc downstream regulated 1 | 0.0504498 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0479042 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0472754 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0470553 |
| KRT17 | keratin 17, type I | 0.046463 |
| RPL12 | ribosomal protein L12 | 0.0464012 |
| RPS13 | ribosomal protein S13 | 0.045909 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0457341 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0456105 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0447649 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0442201 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0437864 |
| RPS21 | ribosomal protein S21 | 0.0426858 |
| TMSB10 | thymosin beta 10 | 0.0423818 |
| ANLN | anillin, actin binding protein | 0.0419231 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0418859 |
| RPL5 | ribosomal protein L5 | 0.0408077 |
| RPS25 | ribosomal protein S25 | 0.0403053 |
| POTEF | POTE ankyrin domain family, member F | 0.0398052 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.039545 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0395058 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0390713 |
| RPLP1 | ribosomal protein, large, P1 | 0.0384666 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.038352 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0383161 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0377563 |
| RPL37A | ribosomal protein L37a | 0.0371723 |
| RPL19 | ribosomal protein L19 | 0.0365141 |
| LMNA | lamin A/C | 0.0364809 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0363982 |
| DSTN | destrin (actin depolymerizing factor) | 0.0363581 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0363525 |
| RPL23 | ribosomal protein L23 | 0.0359725 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0348253 |
| ZNF292 | zinc finger protein 292 | 0.0342739 |
| S100A2 | S100 calcium binding protein A2 | 0.0342051 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0340913 |
| RPL37 | ribosomal protein L37 | 0.0340606 |
| RPS14 | ribosomal protein S14 | 0.0340106 |
| RPL31 | ribosomal protein L31 | 0.0334879 |
| RPS27A | ribosomal protein S27a | 0.0334503 |
| SET | SET nuclear proto-oncogene | 0.0332557 |
| RACK1 | receptor for activated C kinase 1 | 0.03282 |
| CANX | calnexin | 0.0327115 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0324391 |
| S100A9 | S100 calcium binding protein A9 | 0.032321 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.032278 |
| PRRC2C | proline-rich coiled-coil 2C | 0.031921 |
| RPL8 | ribosomal protein L8 | 0.031573 |
| RPL7A | ribosomal protein L7a | 0.0314026 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.031181 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0311065 |
| RPS2 | ribosomal protein S2 | 0.030489 |
| FTL | ferritin, light polypeptide | 0.030294 |
| TPM3 | tropomyosin 3 | 0.0301349 |
| RPS27 | ribosomal protein S27 | 0.0300749 |
| RAI1 | retinoic acid induced 1 | 0.0299691 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0294688 |
| RPS29 | ribosomal protein S29 | 0.0294318 |
| FNIP1 | folliculin interacting protein 1 | 0.0293946 |
| HDGF | hepatoma-derived growth factor | 0.0292456 |
| RAI14 | retinoic acid induced 14 | 0.0291535 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0291362 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0288783 |
| RPL7 | ribosomal protein L7 | 0.0287751 |
| TMF1 | TATA element modulatory factor 1 | 0.0286485 |
| RPL26 | ribosomal protein L26 | 0.0281721 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0278013 |
| RPS23 | ribosomal protein S23 | 0.0275836 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0271532 |
| RPL21 | ribosomal protein L21 | 0.0269552 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0266924 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0266004 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0265875 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0265067 |
| FAM13A | family with sequence similarity 13, member A | 0.0264653 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0262341 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.122145 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0788527 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0694128 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0688611 |
| OSMR | oncostatin M receptor | -0.0592838 |
| FOXO1 | forkhead box O1 | -0.057807 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0512941 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0497068 |
| RIGI | RNA sensor RIG-I | -0.0436865 |
| LMO7 | LIM domain 7 | -0.0433754 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0417713 |
| AOPEP | aminopeptidase O (putative) | -0.041754 |
| SMAD3 | SMAD family member 3 | -0.040061 |
| PLEC | plectin | -0.0392761 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0363923 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0354554 |
| LAMA5 | laminin, alpha 5 | -0.0349626 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.034897 |
| SULF2 | sulfatase 2 | -0.0340021 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0330096 |
| PALLD | palladin, cytoskeletal associated protein | -0.0324466 |
| AMOTL1 | angiomotin like 1 | -0.0317802 |
| RASAL2 | RAS protein activator like 2 | -0.0316426 |
| INTS6 | integrator complex subunit 6 | -0.0301098 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0300298 |
| BLCAP | bladder cancer associated protein | -0.0299712 |
| EGR1 | early growth response 1 | -0.0283283 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0271359 |
| MECOM | MDS1 and EVI1 complex locus | -0.0271332 |
| VCL | vinculin | -0.0270073 |
| ACTN4 | actinin, alpha 4 | -0.0267658 |
| FLNA | filamin A, alpha | -0.0267288 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0266591 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0260682 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0260534 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0257603 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0255506 |
| ARF1 | ADP-ribosylation factor 1 | -0.0255281 |
| CLIC4 | chloride intracellular channel 4 | -0.0249618 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0241516 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0238145 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0235797 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0235333 |
| NEK7 | NIMA-related kinase 7 | -0.0232914 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0229212 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0227979 |
| PLXNA2 | plexin A2 | -0.0227974 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0226574 |
| DGKH | diacylglycerol kinase, eta | -0.0220286 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0218842 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0217276 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0213357 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0213102 |
| IFI44 | interferon-induced protein 44 | -0.0210385 |
| CORO2A | coronin, actin binding protein, 2A | -0.0207935 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0197223 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.019599 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0195609 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.019392 |
| TJP1 | tight junction protein 1 | -0.0193376 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0191855 |
| FN1 | fibronectin 1 | -0.0189038 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0188128 |
| EFNA5 | ephrin-A5 | -0.0186233 |
| PLSCR1 | phospholipid scramblase 1 | -0.0185251 |
| NRCAM | neuronal cell adhesion molecule | -0.0184926 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0184078 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0183552 |
| SDCBP | syndecan binding protein (syntenin) | -0.0181883 |
| CD44 | CD44 molecule (Indian blood group) | -0.0179862 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0177583 |
| EGFR | epidermal growth factor receptor | -0.0177417 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0175959 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0171184 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0168601 |
| NAV2 | neuron navigator 2 | -0.0166601 |
| JMJD1C | jumonji domain containing 1C | -0.0166471 |
| SP100 | SP100 nuclear antigen | -0.0166339 |
| LDLR | low density lipoprotein receptor | -0.0164282 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0161597 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0161577 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0156579 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0154089 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0153638 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.0153374 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.0153363 |
| CTBP2 | C-terminal binding protein 2 | -0.0152947 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0151576 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.0151428 |
| FOXP1 | forkhead box P1 | -0.0151162 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0150053 |
| PITPNB | phosphatidylinositol transfer protein, beta | -0.0149979 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.014853 |
| EXOC4 | exocyst complex component 4 | -0.0148115 |
| AFAP1L2 | actin filament associated protein 1-like 2 | -0.0147032 |
| ACTN1 | actinin, alpha 1 | -0.0146309 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0145835 |
| EXOC6B | exocyst complex component 6B | -0.0145368 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0144669 |
| TAPBP | TAP binding protein (tapasin) | -0.0142808 |
